Adolescent ; Humans ; Lung ; diagnostic imaging ; pathology ; Lung Neoplasms ; diagnostic imaging ; pathology ; surgery ; Male ; Papilloma ; diagnostic imaging ; pathology ; surgery ; Pneumonectomy ; methods ; Tomography, X-Ray Computed

Many problems have been found in the inspection of assets in universities conducted　by the Ministry of Finance,Accordingly,some measures were taken to solve the problems,and as a　result the management was enhanced and the efficiency of the assets were improved.The author,　working in the front line of the inspectiong,reported the experience and in-depth reflection over the　experience to propose for the management of laboratories in medical colleges.

MicroRNA (miRNA) constitutes a group of small (21-23 nucleotide) noncoding RNAs that functional as posttranscriptional gene regulators.miRNA involved in the tumor development which have been suggested to play a vital role in operating to promote or suppress tumor proliferation,invasion and metastasis.The application value of miRNA as a potential biomarker was also discussed.It needs to be further explored that miRNA can be applied as biomarkers in further medical paractice.

Objective To investigate the clinical characteristics of the patients with central brain herniation,and the operation effect of high coronary craniotomy for bilateral decompressive craniectomy.Methods A retrospective analysis was conducted on 26 cases of central brain herniation.The effectiveness of high coronary craniotomy for bilateral decompressive craniectomy and the influential factor of prognosis in patients with central brain herniation were analyzed.Results According to the Glasgow outcome score (GOS) 6 months after operation,5 cases were recovered well,6 cases moderately disabled,4 cases severely disabled,3 cases vegetative survived and 8 cases died.Conclusions High coronary craniotomy and timely and effective bilateral decompressive craniectomy are the most important treatment in patients with central brain herniation.The prognosis is unfavourable prognosis in patients with central brain herniation within 1 h after injury and older than 75 years old.

The rashness in research as reflected in the initial misidentification of the pathogen of SARS is of great enlightening and warning significance to scientific and technical workers in the medical field. In order to effec-tively reduce errors in the clinical diagnosis of SARS, succeed in obtaining reliable methods for its specific diagnosis, and strive for a genuine victory in the fight against it, it is imperative to vigorously uphold the scientific spirit of adher-ing to truths and defying authorities and promote the style of doing things in a rigorous, realistic, accurate, persistent and down-to-earth manner. Rashness must be avoided by all means.

In order to evaluate appropriately the role of lipid metabolism by the refined konjac meal (RKM), a new source of dietary fiber, the effects of RKM on the level of serum and liver lipids, hepatic histopathology and on the composition and output of fecal bile acids in comparison with pectin, algin and agar were studied.The RKM contained about 75-80% of glucomannan. All four kinds of dietary fiber "were given at a level of 5% in the diet to the young male Wistar rats fed on a lipid-rich diet containing 5% lard, 1% cholesterol and 0.25% chplate. The control group was fed on a lipid-rich diet alone withput fiber. The normal group was fed on a basal diet without extra lipid added. Feeding period was 9 weeks.The results obtained were as follows;1)All the dietary fibers tested have the similar effects on serum lipid composition. At the end of 2-week of the experiment, the serum total cholesterol levels of the four experimental groups were only 62% to 75% of that of the control group, and at the end of 7-week they were lowered to the same level of the normal group. The level of the triglyceride in serum did not change in all groups during the experiment.2)Relative liver weights were lower in four experimental groups than in control group. Hepatic hisiopathological examinations showed lipotropic effect in RKM, pectin and algin groups. Both of the above effects appeared most significantly in RKM group. The concentrations of total cholesterol and triglyceride in liver in RKM group were lower than those in control group as well as other three experimental groups.3)No harmful effects on the intake of food and growing of rats were found when feeding these four kinds of dietary fiber at the level of 5%.4)The daily output of fecal bile acids (CDCA + GDCA) was significantly increased in four experimental groups.The increase of fecal output of bile acids, especially CDCA, may be one of the mechanisms of hypocholesterola-emic effect of dietary fibers.It could be concluded that RKM has the same significant hypocholestero-lemic effect as the pectin, algin and agar, but its lipotropic effect is more potent.

Objective:Heart rate variability (HRV) contains a lot of information concerning the cardiovascular regulation,and can be an important indicator,quantitatively reflecting of autonomic nervous function and the normal heart activity,also can play an important role in cardiovascular regulation.Therefore,HRV signals are analyzed using common HRV analysis methods.Methods:Decompose HRV signals of congestive heart failure and normal persons into 6 scales using Multi-resolution analysis.The wavelet coefficient energy is calculated,especially the frequency energy of cd3 to cd6.Results:Energy is mainly concerned in the lower band of high frequency band and low frequency band,where the energy differences between the two groups are more evidence.It's more precise compared to the result with frequency-domain analysis.Conclusions:To gain results with universal law,more different analysis methods need to be improved and lots of researches are necessary.

Objective To investigate the expression and clinical significance of Bmi-1,Podoplanin and p53 in human thymic epithelial tumor(TET) according to new histological classification of World Health Organization. Methods One hundred and ten TET tissue chips were prepared,and the expressions of Bmi-1,Podoplanin and p53 were detected by NovoLinkTM Polymer detection systems. Results The positive expressions of Bmi-1,Podoplanin and p53 were 68.2%,41.8% and 42.7%,respectively.The positive expressions of Bmi-1,Podoplanin and p53 were significantly associated with pathologic histological classification,Masaoka staging and clinic pathological grading(P

In this experiment,the bone marrow cell of C_(57) species of purity rat is used as a material and the micronucleus is used as an index,the prescriptions of Shengmai Powder,etc.were continuesly studied under the basis of some tonic prescription study.The result indicated the Shengmai Powder showed the inhibition on micronueleus induced by cyclophosphamide.

Objective To analyze the clinical effect and safety of cortical bone decortication combined locking plate fixation for treatment of long bone nonunion of limbs. Methods Eighty patients with long bone nonunion of limbs who were treated in the Zhongshan Hospital Affiliated to Dalian University from Jun. 2010 to Jun. 2013 were selected as our subjects and their clinical data were recorded. According to different treatment methods,the patients were divided into control group and observation group,and each group with 40 cases. Patients in observation group were treated with cortical bone decortication combined locking plate fixation, while in control group were treated with locking plate combined slotted bone graft. Clinical effects and safety of two groups were compared. Results Excellent and good rate in observation group was 100%(40/40),obviously higher than that of control group(90. 0%(36/40);χ2 =4. 21,P﹤0. 05). Bleeding amount during operation in observation group was(370. 5 ± 56. 5)ml,obviously less than that of control group((486. 5 ± 64. 5)ml;t=8. 56,P﹤0. 01). And the fracture healing time was(5. 6 ± 1. 2)months in observation group,shorter than control group((7. 2 ± 1. 5)months;t =5. 27,P ﹤0. 01). The postoperative complication occurrence rate was 5. 0%(2/40),significantly lower than control group(20. 0%(8/40);χ2 =4. 11,P ﹤0. 05). Conclusion Cortical bone decortication combined locking plate fixation for treatment of long bone nonunion of limbs is safe and effective,and it can reduce operation injury and accelerate postoperative healing of fracture.