1.Application effect of clinical pathways in children with bronchopneumonia: a Meta-analysis
Zhongbin TAO ; Jing MAO ; Jichun MA
Chinese Pediatric Emergency Medicine 2014;21(10):641-645
Objective To evaluate the application effect of clinical pathways (CP) in children with bronchopneumonia.Methods The literature of randomized controlled trials (RCTs) in children with bronchopneumonia were retrieved by searching PubMed,Cochrane Library,Web of Knowledge,Wanfang database,VIP,and CNKI from their inception date to March 2014.Meta-analysis was performed by Revman 5.2software.Results Six RCTs involving 24 559 patients were finally selected,with 12 269 cases in the CP group and 12 290 cases in the traditional treatment group.The results of Meta-analysis showed that there were significant differences between the CP group and the traditional treatment group in the cure rate [OR =1.67,95 % CI (1.03,2.77),P =0.04],length of hospital stay [MD =-1.21,95 % CI (-1.95,-0.48),P =0.001],hospitalization expenses [SMD =-3.68,95 % CI (-5.04,-2.32),P < 0.000 1],days of antibiotic using [MD =-1.20,95 % CI (-1.51,-0.89),P < 0.000 01] and patient satisfaction [OR =6.12,95 % CI(3.12,12.04),P < 0.000 01].Conclusion CP is superior compared with the traditional treatment for bronchopneumonia,and is worthy of spread in clinical.
2.Cardioprotective effects of SF pretreatment mediated by bradykinin on isolated rat heart
Jichun LIU ; Tao GAO ; Lijian SHAO ; Ming HE
Chinese Pharmacological Bulletin 2003;0(09):-
0.05). Conclusions One mechanism of SF pretreatment cardioprotective effect is mediated by bradykinin. The combined use of SF and CP doesn′t result in significant improvement, and thenefore is not advocated.
3.Orthotopic heart transplantation in 3 cases
Jichun LIU ; Jianjun XU ; Yuhua WAN ; Huageng RAO ; Qin WANG ; Zhiping LI ; Sheng LIU ; Qicai WU ; Tao GAO ; Gan CHEN
Chinese Journal of Tissue Engineering Research 2009;13(5):997-1000
Three cases of terminal stage heart disease received orthotopic heart transplantation at the Department of Cardiothoracic Surgery, the First Hospital of Nanchang University between August 2001 and December 2003. These three cases were all female and died of brain death. Body weight difference between donor and recipient was less than 20%. All three cases underwent superior and inferior vena cave osculation and received immunosuppressive therapy of cyclosporine A, prednisone, and mycophenolate postoperatively. They were successfully discarded. Heart function recovered to grade Ⅰ-Ⅱ(NYHA). No infection or serious rejection was found during the surgery. These results indicate that good donor heart preservation, consummate perioperative processing, and proper immunosuppressiva therapy are the key measures of successful heart transplantation.
4.Epidemic and clinical characteristics of hemorrhagic fever with renal syndrome in southern Anhui Province
Jichun TAO ; Jinsun YANG ; Entao SUN
Journal of Public Health and Preventive Medicine 2022;33(1):103-106
Objective To analyze and study the epidemic and clinical characteristics of hemorrhagic fever with renal syndrome in Southern Anhui Province during 2010-2020. Methods The epidemiological and clinical data of HFRS patients hospitalized in Yijishan Hospital of Wannan Medical College from 2010 to 2020 were collected and statistically analyzed. Results The temporal distribution of HFRS epidemic in Southern Anhui Province showed that HFRS were more frequent during spring and summer, and HFRS morbidity was highest in June. The population distribution characteristics showed that the ratio of male to female patients was 4.7:1. The main age group of patients was 40-50 years old (50 cases, 33.8%), and a majority of patients were farmers (87 cases, 58.78). Analysis of clinical characteristics showed that fever, backache, anorexia and hypodynamia, diarrhea, emesis and headache were the main frequent symptoms of HFRS patients, and 88.52% of HFRS patients were cured or improved. Conclusion The high incidence period of HFRS is spring and summer in Southern Anhui Province from 2010-2020. HFRS patients in Southern Anhui Province have typical clinical symptoms and good prognosis.