Objective:To observe the in fluence of atorvastatin on serumlevels of IL-1?,TNF-?,OX-LDLand serumlipid in cerebral spontaneous hemorrhage to study its protection mechanisms for cerebral spontaneous hemorrhage.Methods:Sixty patients with cerebral hemorrhage were divided into normal serum lipid level group with cerebral spontaneous hemorrhage(A),and higher serum lipid level group with cerebral spontaneous hemorrhage(AH),normal serum lipid level cerebral spontaneous hemorrhage group with atorvastatin treatment(AT),and higher serum lipid level cerebral spontaneous hemorrhage group with atorvastatin treatment(AHT).Neurological deficiency score was examined.IL-1?,TNF-?,and OX-LDL were measured by enzyme linked immunosorbent assay;and serum lipid level was measured by biochemistry.Results:The serum levels of IL-1?,TNF-?,and OX-LDL in AT group were significantly decreased compared with those of A group(P0.05);The serum levels of IL-1?,TNF-?,and OX-LDL in AHT group were significantlylower than those in AH group,and compared with those at 2w,all the levels at 4wand 6wwere significantly lowe(rP

Objective:To investigate the changes of Livin,VEGF, interleukin(IL)-18 and interferon(IFN)-? in the plasma of patients with vascular dementia, and to observe role of Livin,VEGF,IL-18 and IFN-? in the pathogenesis of vascular dementia. Methods:Enzyme-linked immunosorbent assay(ELISA) was used to detect the concentration of Livin,VEGF, IL-18 and IFN-? in the serum of patients with vascular dementia. Results:Serum level of Livin and VEGF in the patients with vascular dementia were significantly lower than the control group(P