Objective:To evaluate the effect to treatment adherence of defaulter action implement for patients with Tuberculosis in Chongqing and explore a proper cure management system to timely find out the TB patients who stop picking medicine on time;Methods:Carrying out intervention method to TB patients with positive sputum in intervention counties,then using qualitative study to analysis the effect of implementing the intervention;Results:After the intervention,the adherence of TB patients is obviously improved;Conclusion:Proposed method is a effective and feasible management to the TB patients who stop picking medicine during anti-TB treatment,which bring positive effect on TB patients' adherence and TB cure rate.

Comprehensive evaluation for colleges of stomatology is a complex systematic engineering, which is affected by the determination of index and weight. Based on the previous research results,this study establishes a comprehensive evaluation index for colleges of stomatology in China by applying Delphi method,carrying out two-round consultation to 45 experts,which includes 4 first layer indicators and 21 second layer indicators.

Objective To investigate the risks of HBV infection among the spouses of HBV surface antigen (HBsAg)carriers and to find out effective control strategies on hepatitis B control and prevention .Methods To use case-control study(1∶2) including spouses of HBsAg carriers aged 18 -59 years-old from the nationwide sero-epidemiological survey for Hepatitis B in Chonqing province in 2005 ,and the spouses of the healthy(HBsAg negative persons)as the control groups ,adopt euzymelinked immunosor-bent assay(ELISA) to carry out the sero-epidemiological testing (HBsAg ,anti-HBc ,anti-HBs) for Hepatitis B .Results The posi-tive rate of HBsAgamong the spouses of HBsAg carriers (14 .8% ) was higher than the rate of spouse among the healthy (7 .5% ) , with difference statistically significant (P<0 .01) ,the positive rate of HBsAg in female spouse was uptrend as the marriage age grown ,multiple factor analysis found that the risks of HBV infection among the spouses were their spouse with HBsAg and without condom when the sexual behavior .Conclusion The spouses of HBsAg carriers have high risks of HBV .Premarital examinations , safety sexual behaviors with condom ,timely hepatitis B vaccination etc .are helpful for the spouses of HBsAg carriers free of hepati-tis B virus ,especially female spouses should insist on using condom when the sexual behavior because of them easier to be infected by the hepatitis B virus .

Objective To evaluate the work effect after supplementary immunization activities (SIAs) of Hepatitis B vaccine , thus to find the focal point in future hepatitis B prevention .Methods useing statistical method to analysis the data of investigation from 2004 to 2012 of hepatitis B vaccination rate ,the data of selective SIAs of hepatitis B vaccine and the incidence of hepatitis B . Results With the supporting of GAVI project ,the whole course vaccination rate and the timely first dose rate of hepatitis B were obviously increased(P<0 .01) ,supplementary immunization rate of hepatitis B was increased year by year and the incidence of hep-atitis B among 0-14 years old children decreased at 78 .42/100 ,000 .Conclusion The vaccination rate of hepatitis B shows a high and stable trend in Chongqing ,but we need to form a long term mechanism without project supporting to push forward hepatitis B prevention for the newborn .And on the base of doing good jobs in hepatitis B vaccination for the newborn ,we should also expand the hepatitis b vaccination priority to people over the age of 14 .

Objective To analyze the epidemiological characteristics of rubella since 2008 ,while the vaccine first used in Chongqing .Methods Descriptive epidemiological study was applied to analyze the cases on rubella from 2008 to 2013 ,and the Excel was used for data analysis .Results From 2008 to 2010 ,the rubella incidence rate reported in Chongqing decreased from 18 .97 per 100 000 to 2 .07 per 100 000 ,but it gave a rebounding trend in 2011 to 2012 .The rubella cases mostly affected children of 6 -14 years old and the epidemic peak was from April to June .Although ,the vaccination rate of rubella increased year by year from 2008 to 2013 ,even in 2012 it reached up to 90% ,but the vaccination coverage was low in primary and middle schools .100 epidemic out‐breaks happened ,91% of which happened in primary and middle schools ,accounting for 18 .74% of all reported cases .Conclusion Students in primary and middle school were easily infected with rubella virus ,the vaccination work should be strengthened for fur‐ther control the rubella infection .Secondary immune of Rubella vaccine of 6 or 7 years old children will contribute to control the outbreak of rubella among school‐age children ,and the rubella vaccine should expand its immunization objects .

Objective To observe the influence of Electro-Acupuncture on free amino acid in brain tissue of diabetic rats. Method The diabetic rats were induced by the intra-abdominal injection of alloxan (100 mg/kg once a day for two days). Electro-Acupuncture on Bai Hui and Da Zhui together with quick puncturing along Pang Guang meridian on the back, especially the back Shu points of five Zang organs were applied to alloxan-diabetic rats. Blood glucose and free amino acid were investigated after 6 weeks of Electro-Acupuncture treatment. Results The blood glucose of Electro-Acupuncture group was decreased obviously after treatment (P

Objective To explore the imaging appearances of periprosthetic osteolysis after total hip arthroplasty(THA).Methods Imaging appearances of periprosthetic osteoleysis after THA in 24 cases confirmed by surgery and pathological examination were retrospectively analyzed.Twenty-four patients underwent X-ray examinations,and 17 of them underwent CT scanning additionally.Results (1) Location and type:Of the 24 cases with periprosthetic osteoleysis,23 femurs were involved (95.8％,expansile type in 15 cases and liner type in 8 cases).Lesions were located in Gruen 1-2 and 6-7 region (34.8％) in 8 cases,in Gruen 1 and 7 region in 8 cases (34.8％),in Gruen 1-7 region in 6 cases (26.0％),in Gruen 2-3 and 6 region in one case (4.3％).A total of 21 actabulums were involved (87.5％,expansile type in 14 cases and liner type in 7 cases included),with lesions located in Delee Ⅰ-Ⅲ in 14 cases (66.7％),in Delee Ⅰ and Ⅲ in 4 cases (19.0％),in Delee Ⅱ-Ⅲ in 2 cases (9.5％) and in Delee Ⅰ-Ⅱ in 1 case (4.8％).(2) Features of lesions:Adjacent cortex of the lucency lesion appeared irregular thin in 24 cases (100％),focally discontinuous in 18 cases (75.0％),disrupted in 16 cases (66.7％),and accompanied by a few tiny bony fragments in 10 cases (41.7％).Cortical thickening were seen near the lucency lesion in 3 cases(12.5％).Twenty-one cases (87.5％) presented with sclerotic margins,18 cases (75.0％) with crateriform interface.Of the 17 cases which underwent the CT scanning,16 cases (94.1％)had soft tissue mass.(3) Change of the prosthesis:Twenty-one cases (87.5％) presented with linear wear,11 cases (45.8％) with bony defect near the screw.The screw penetration was seen in 3 cases (12.5％),fractured screws were seen in 2 cases (8.3％),and screw invagination was seen in 1 case (4.2％),metal debris was seen in 12 cases (50.0％).(4) Complications:Nineteen cases (79.2％) presented with femur periprosthetic loosening,16 cases (66.7％) with actabulum periprosthetic loosening.Eleven cases (45.8％) presented with femur periprosthetic fractures,5 cases (20.8％) with actabulum periprosthetic fractures.Two cases (8.3％) had periprosthetic dislocation.Conclusions Linear or expansile lucent lesion of the bones around the prosthesis after THA,together with soft tissue mass and the imaging of linear wear can be diagnosed as the periprosthetic osteolysis.

The concept and methods of evidence-based medicine(EBM)has been evolved to impact almost all fields of health care and policy since it first appeared in 1992.but in the field of dentistry or stomatology,many problems remain to be solved in carrying out EBM.The necessity and feasibility of implementing evidence-based dentistry education in China were discussed in this paper for chnical evidence-based decision making and clinical research.The contenk teaching approach and accreditation tools for EBM in dental education were also proposed.

This study aimed to construct throe-dimensional finite element model of the mandibular complete overdenturo and to analyze the influence rules for stress distribution under different mandibular shapes. The layer cutting method was employed as a basic tool to deal with different plaster models to gain two-dimensional point data. These data were introduced to the commercial software ANSYS to construct throe-dimensional finite element model of the mandibular complete overdenturo, including nine kinds of typical shapes, such as sharpness, roundness and squareness, and etc. Static loads were imposed on denture so as to accomplish biomechanicel analysis and to study the influence rules of stress distribution for mandibular complete overdenturo under different mandibular shapes. Results revealed that the sequence of stress from high to low was squareness, roundness, sharpness and the other extrapolated, basic and inside. The throe-dimensional finite element model has high simulation accuracy and the results provide an experimental foundation and guidance for clinical work.

Objective To evaluate reverse effect of recombinant human Endostatin on drug-resistance of A549/DDP cells to cisplatin (DDP). Methods Lung adenocarcinoma cell line A549 and its DDP-resistant cell line A549/DDP were treated with DDP and recombinant human Endostatin. Difference in drug resistance was analyzed between different regimens ( DDP, Endostatin and combination) and between different cell lines ( human lung adenocarcinoma A549 and drug resistant A549/DDP), after a 72h-treatment in vitro. Reverse effect of recombinant human Endostatin on drug-resistance of A549/DDP to DDP was tested by MTT assay. Results The observed 50% inhibitory concentration ( IC50 ) was (0.72 ± 0.05 ) ug/ml against A549 and ( 11.54 ± 0.64)against A549/DDP in DDP, and (2.0 ± 0.1 ) μg/ml against A549/DDP in rh-Endostatin- DDP combination respectively, with a reversal fold (RF) of 5.77 and a relative reversal rate of 88. 2%. Conclusion rh-Endostatin may reverse drug-resistance of A549/DDP cells to DDP.