Gap junction,a special structure in cell membrane,constitutes the only direct communication channel of energy,material and information exchange between adjacent cells.Gap junction plays an important role in the maintenance of electrical activity of neurons,the rapid synchronization of neurons and neuronal development.Epilepsy,caused by a variety of causes,is a complex clinical syndrome.The pathogenesis of epilepsy is complex.And it's still not fully understood.Studies in recent years have found that gap junction plays a very important role in the pathogenesis and development of epilepsy.The structure,distribution and functions of gap junction and the relationship between gap junction and epilepsy are reviewed in the paper.

Mycoplasma pneumoniae is a common cause of pediatric community-acquired pneumonia.It has been associated with various extrapulmonary manifestations.Pediatric mycoplasma pneumoniae encephalitis is the most common neurologic manifestations.Direct invasion,an immune-mediated mechanism,or neurotoxin production has been proposed.Because mycoplasma pneumoniae encephalitis has a high mortality and a high rate of neurological sequelae,improving the clinicians awareness of the disease,minimizing misdiagnosis and missed diagnosis,have important significance.

The author took the medical records of ZHANG Jing-yue,a famous doctor of Ming dynasty,as an example,by analyzing his methods of syndrome differentiation and prescription,and believed that the significance of syndrome difierentiation based on Yin-yang of five viscera in clinical treatment.The key point of TCM treatment is to restore the state of Yin and Yang in a relative equilibrium by enhancing and regulating the functions offive viscera,and so thus to increase the functions of body self-regulating and disease-preventing.

Objective:To evaluate the effect to treatment adherence of defaulter action implement for patients with Tuberculosis in Chongqing and explore a proper cure management system to timely find out the TB patients who stop picking medicine on time;Methods:Carrying out intervention method to TB patients with positive sputum in intervention counties,then using qualitative study to analysis the effect of implementing the intervention;Results:After the intervention,the adherence of TB patients is obviously improved;Conclusion:Proposed method is a effective and feasible management to the TB patients who stop picking medicine during anti-TB treatment,which bring positive effect on TB patients' adherence and TB cure rate.

Improving the innovation ability of students is always concerned by the educators in the modern times.In the paper,the problem of how to train the innovation ability of students in the experiments of Instrument Analysis is discussed from the following five aspects:course innovation,expending the thinking,strengthening the experiment skills,creating the innovation environment and exchanging the experiences.

Lu Zhaolin professor thinks,at present,according to the efficacy of traditional Chinese medicine classification method is not conducive to a comprehensive understanding and grasp of the knowledge of traditional Chinese medicine in clinical application.Understanding of the efficacy of traditional Chinese medicine,we should start from the overall regulation of drugs on the human body,and make full use of the theory closely related to traditional Chinese medicine properties such as the four properties and five tastes,ascending-descending-floating-sinking,medicinal guide,etc.Meanwhile the modern pharmacological research achievements should be taken to accurately grasp the efficacy of traditional Chinese medicine.

With the progress of technology in separation and identification, proteomics is now widely applied in biomedicine.Because of the powerful ability to research differential protein expression and posttranslational modifications between normal and pathological samples on large scale level, proteomics provides the possibilities to screen biomarkers for diagnosis, therapy or prognosis of diseases.

In recent year , there are some questions about abortion of disposal .Though the aborted fetus is un-born, the aborted fetus in different stage has the different attribute of ethics .It should be considered with the hu-man right and the personality right .The value in embryonic stem research and organ transplantation of aborted fetus has raised some problems , such as ethical review , the choice of test sample .The existing legal provisions are not sufficient to solve practical problems .We should disposal aborted fetus of different stage through the way of more moral significance .

Positive and meaningful exploration was conducted by related teachers to improve the teaching quality of oral clinical pharmacology.Case based teaching method was applied in the teaching of adverse reactions and bilingual teaching was employed in the teaching of local anesthesia.Correlation and comparison of the key knowledge points were emphasized in the teaching process. Students′ interests were aroused and satisfactory results were achieved through implementing these measures.

The combination of medical humanistic spirit and medical scientific spirit is the sign of the maturity of medicine.The modern medical mode of ' biology-psychology-society-environment' sets new requirements for medical humanistic education.Clinic medical postgraduates,the front -line medical workers,play a very important role in medical work,but they show huge deficiency in interpersonal communication,humanistic knowledge and humanistic possession nowadays.The paper tried to draw some lessons from the successful education mode of George Washington university and discussed practicable methods to improve humanistic education among medical postgraduates aiming at cultivating qualified medical workers who have both noble medical ethics and perfect medical technology and ability.