Objective To study the feasibility and safety of transumbilical single port laparoscopic cholecystectomy(LC).Methods We analyzed the clinical data of 52 cases of transumbilical single port LC done in our hospital from March 2009 to July 2009.Results Three cases were operated by usual LC becauseof stone embedded in gallbladder neck and exposure was difficult.In the other 49 cases(94.2%),transumbilical single port LC was successfully performed.Operating time was 39 to 108 min[mean(48?23 min)].There were no intraoperative complications.The patients were discharged from hospital in one to three days after operation,and resumed normal work in one week.Conclusions Compared with the routine LC,transumbilical single port LC is more feasible,has more micro-invasive advantages and with no visible abdominalscar.