Objective To explore the clinical value of early arterial phase (EAP) enhanced imaging with MSCT in detecting liver focal lesions.Methods 100 patients with liver focal lesions were examined with MSCT scan.The images were analyzed.Results There were 85.0％ of the 100 cases that demonstrated EAP enhancement,which was hemangioma of liver(100.0％),hepatapostema (100.0％),hepatocellular carcinoma (95.0％),liver metastasis (84.0％),and cholangiocellular carcinoma(25.0％) in descending order.The abnormal vascular lesions and heterogeneous enhancement had high sensitivity and specificity for hepatocellular carcinoma,and the edge nodular enhancement for hemangioma,and the ring enhancement for metastases.Conclusion The EAP enhanced imaging with MSCT in detecting liver focal lesions has great applicative value.