Objective To observe the effect of externally-applied gallnut powder on Shenque integrated with orally-administeredWuhong Decoctionon sweat syndrome of cancer patients and summarize its nursing points. Methods Sixty patients were randomly divided into the control group and the therapeutic group, each with 30 patients. The therapeutic group was treated with externally-applied gallnut powder on Shenque and medication of'Wuhong Decoction'apart from the conventional treatment which was only used in the control group. The two groups were compared in terms of the situation of spontaneous sweat and night sweat and score of dizziness. Result The effects of spontaneous sweat and night sweat in the therapeutic group were better than those of the control group (P<0.05). Conclusions Externally-applied Gallnut powder on Shenque combined with medication ofWuhong Decoction can be effective in the treatment of sweat syndrome of cancer patients. It can help them to regain their physical power and then strengthen their resistance against diseases and finally enhance their quality of life.