1.Correlation analysis between ALT and viral hepatitis in blood screening among blood donors
Jiaomei XIONG ; Xin ZHENG ; Ailian YANG ; Tianli WEI
International Journal of Laboratory Medicine 2015;(7):867-869
Objective To study the correlation between alanie aminotransferase(ALT) unqualified samples and hepatitis B sur‐face antigen(HBsAg) and hepatitis C virus antibody (anti‐HCV) detection and to investigate an effective measure for reducing the discard rate of donated blood .Methods 330 633 blood samples donated by volunteers in Shenzhen Municipal Blood Center from January 1 ,2009 to December 31 ,2013 were performed the ALT ,HBsAg and anti‐HCV detection .Then the correlation between the detection results of ALT and viral hepatitis .Results Among 33 0633 donated blood samples ,there were 932 cases (0 .282% ) of ALT positive and 2 965 cases (0 .897% ) of viral hepatitis positive ,the differences were statistically significant (P<0 .05) .915 cases were unqualified in ALT ,but negative in viral hepatitis ,which accounting for 98 .176% of all ALT unqualified samples ;the blood discard rate generated by ALT disqualification was 0 .277% (915/330633) .Conclusion Our study indicates that the statistical difference exists in the ALT unqualified rate and the viral hepatitis detection rate ,conducting the ALT detection has the lower coin‐cidence rate for expected viral hepatic ,many false positive lead to the discard of normal blood .Therefore ,whether to continue using the ALT detection as the auxillary detection indicator is still being negotiated .
2.Prenatal exposure to outdoor air pollution and preterm birth: a Meta-analysis
Yu CHEN ; Baibing MI ; Yaling ZHAO ; Jiaomei YANG ; Yali TAO ; Hong YAN
Chinese Journal of Epidemiology 2016;37(6):880-885
Objective To assess the association between exposure to prenatal outdoor air pollution and preterm birth to provide evidence in setting up programs for prevention on premature birth.Methods Case-control studies regarding association between pregnant exposure to outdoor air pollution and preterm birth were collected.Data were analyzed with Stata 12.0.Results Ten articles including 48 556 cases and 548 495 controls were qualified for inclusion.Results from Meta-analyses showed pooled ORs for exposure to NO2,PM10,CO,PM2.5,and NO during the entire pregnancy were 0.960 (95%CI:0.935-0.985),1.068 (95%CI:1.035-1.103),1.122 (95%CI:1.078-1.168),1.110 (95% CI:1.043-1.181) and 0.994 (95% CI:0.973-1.016).Association between air pollution and preterm birth varied with the periods of exposure.Pooled ORs for NO2,PM10 and SO2 exposure during the first trimester were 1.117 (95%CI:1.052-1.186),0.968 (95%CI:0.812-1.153) and 1.258 (95%CI:0.758-2.089).Pooled ORs for NO2,PM10,SO2 exposure during the second trimester were 1.000 (95% CI:0.982-1.019),1.127 (95% CI:0.896-1.416) and 0.977 (95%CI:0.711-1.342).Pooled ORs for NO2,PM10,SO2 exposure during the third trimester were 1.006 (95%CI:1.002-1.010),1.053 (95%CI:0.973-1.139) and 1.003 (95%CI:1.000-1.006).Conclusion Exposures to PM10,CO and PM2.5 during the entire pregnancy,to NO2 during the first trimester,or to NO2 and SO2 during the third trimester were associated with preterm births.
3.Investigation of Chinese residency training program of radiation oncology
Yuexin YANG ; Jiaomei ZHOU ; Ye ZHANG ; Jun LIANG ; Zhijian CHEN ; Jing JIN
Chinese Journal of Radiation Oncology 2022;31(9):772-777
Objective:To evaluate the compliance with Chinese Residency Training Program of radiation oncology and provide reference for the improvement of system reform and base construction.Methods:An survey was conducted among residents who had completed residency training program of radiation oncology by online questionnaires in four dimensions, including the fulfillment of training center in hardware, personnel and procedures, the compliance with syllabuses, mechanism of trainee evaluation, and the passing rate and satisfaction degree of trainees.Results:The results showed that most training centers fulfilled the requirement of equipment, mentoring personnel and procedures. The training syllabuses had been followed and integrated with organization multi-modalities. The trainees with high degree of satisfaction accounted for 65.6%, and the final qualification passing rate reached 75.5%. However, there were less reference textbooks, insufficient training in general medicine, limited clinical practice, and low output in academic publication.Conclusions:The residency training program of radiation oncology has been established in China and achieved notable progress. For the further improvement, quantitative optimization of procedures, increasing opportunity of practice and strengthening scientific research involvement would be beneficial.
4.Evaluation of diet quality among pregnant women in Shaanxi Province by Diet Balance Index for Pregnancy
Qianqian CHANG ; Shaonong DANG ; Hong YAN ; Lingxia ZENG ; Jiaomei YANG
Journal of Xi'an Jiaotong University(Medical Sciences) 2022;43(5):744-751
【Objective】 To evaluate the diet quality of pregnant women in Shaanxi Province by Diet Balance Index for Pregnancy (DBI_P) and investigate the influencing factors. 【Methods】 By using a multi-stage stratified random sampling method, 7375 pregnant women in 30 districts (counties) of Shaanxi Province were recruited. A structured questionnaire was adopted to collect general information in pregnancy, and a semi-quantitative food frequency questionnaire was used to obtain dietary information in pregnancy. DBI_ P was used to evaluate the diet quality during pregnancy, and the factors influencing diet quality were assessed by multiple linear regression. 【Results】 More than 50% pregnant women had inadequate intakes of dairy products, fish and shrimp, meat and poultry, vegetables, eggs, fruits and diet variety. More than 69% pregnant women had excessive intakes of cooking oil, cereals and salt. The average values of high bound score, low bound score, and diet quality distance were 12.9, 19.5, and 32.5, respectively. The proportions of medium inadequate, excessive, and imbalance of dietary intakes were 20.3%, 22.55%, and 40.8%, respectively. DBI_LBS during pregnancy was negatively correlated with childbearing age, education level, family per capita annual income, antenatal examination frequency and folic acid supplementation, but positively correlated with living in southern and northern Shaanxi, residing in rural areas, being farmers, and drinking alcohol. DBI_HBS during pregnancy was negatively correlated with living in southern and northern Shaanxi, but positively correlated with active/passive smoking and drinking strong tea. DBI_DQD during pregnancy was negatively correlated with education level, family per capita annual income, antenatal examination frequency and folic acid supplementation, but positively correlated with living in southern Shaanxi, residing in rural areas, being farmers, parity, active/passive smoking, and drinking strong tea and coffee. 【Conclusion】 The dietary intake of pregnant women in Shaanxi Province was insufficient and unbalanced, and the dietary quality was affected by sociodemographic and life behavior factors during pregnancy. Nutritional intervention measures should be targeted.