Objective:To retrieve and evaluate the evidence related to the use of micropumps in vasoactive drugs, and summarize the best evidence at home and abroad.Methods:Evidence related to the use of micropumps in vasoactive drugs published up to November 27, 2020 was systematically retrieved from databases such as UpToDate, International Guidelines Collaboration, Scottish Intercollegiate Guidelines Network, National Guidelines Repository, Ontario Registered Nurses Association, American Society for Intravenous Infusion Nursing, US Food and Drug Administration, Cochrane Library, OVID-JBI, PubMed, Embase, Web of Science, CINAHL, China National Knowledge Infrastructure (CNKI) , VIP, and SinoMed. The quality and level of evidence were evaluated using the authenticity evaluation tool and evidence grading system of the Australian JBI Evidence-Based Health Care Center.Results:A total of 30 literatures were included, and 28 pieces of evidence were summarized from three aspects: education and training, process of micropump use, and micropump management.Conclusions:The clinical practice of micropump infusion of vasoactive drugs based on the best evidence requires the cooperation of multidisciplinary teams. It is necessary to carry out relevant education and training, formulate and implement a systematic micropump management strategy, which can continuously promote the safety and effectiveness of micropumps in vasoactive drugs.