Abnormal reaction in preventive vaccination is the serious adverse reaction happened in regular vaccination. Department of government and producer of vaccines are liable legislatively. In my opinion, relief fund for abnormal reaction should be established to cover the damage of victims and to decrease the risk of government and enterprises.

Objective To establish a new approach based on mathematical morphology that can effectively reduce the drifts in functional magnetic resonance imaging (fMRI) signals. Methods Based on investigation of the characteristic of drifted fMRI signals, a mathematical morphology method for baseline drift correction was presented. Results With both simulated data and real fMRI data, the results of the experiment showed that the mathematical morphology method can effectively correct the baseline drifts. Conclusion Both linear and nonlinear drifts can be removed with the proposed method without any statistical model assumption.

BACKGROUND:Recombinant human epidermal growth factor has been shown to promote granulation tissue formation and to accelerate the healing of burn wounds, but the antibacterial effect of recombinant human epidermal growth factor is limited. OBJECTIVE:To investigate the effect of nano-silver dressing combined with recombinant human epidermal growth factor gel in treatment of burns and the influence on the scar. METHODS:A total of 76 cases of shal ow II and depth II degree were randomly enrol ed and assigned to two groups. In the study group, recombinant human epidermal growth factor was coated on the surface of the wound, and then covered by nano-silver dressing. In the control group, recombinant human epidermal growth factor was coated on the surface of the wound, and covered by ordinary sterile gauze. The healing time, the positive rate of bacteria, scarring and adverse reactions were compared between the two groups. RESULTS AND CONCLUSION:The wound healing time and the rate of hypertrophic scars after healing were lower in the study group than in the control group (P<0.01). The rate of flat scar was greater in the study group than in the control group after healing (P<0.01). The bacterial positive rate was significantly lower in the study group than in the control group at 7, 14 and 21 days after treatment (P<0.05). No significant difference in incidence of al ergies and local burning sensation was detected between the two groups (P>0.05). These data confirmed that recombinant human epidermal growth factor gel combined with nano-silver dressing in the treatment of burn has good efficacy and accelerates the wound healing, reduces scar formation, and improves aesthetics.

Objective To investigate the effect of 3 concentrations of sevoflurane pretreatment on acute lung injury induced by endotoxin in rats. Methods Thirty-six male SD rats were randomly divided into 6 groups:a control group(Group A), a sevoflurane group(Group B), a 3.6% sevoflurane pretreatment group(Group C), a 2.4% Sevoflurane pretreatment group(Group D), a 1.2% sevo sevoflurane pretreatment group(Group E), and lipopolysaccharide (Group F).The rats were killed 6 h after lipopolysaccharide (LPS) or saline injection.Histological examinations of the lung tissues were performed with light microscope. Lung wet/dry weight (W/D) ratio, myeloperoxidase (MPO) activity, and intercellular adhesion molecule 1 (ICAM-1) mRNA expression were assayed. Results Introvenous LPS significantly aggravated lung tissue damage,increased lung W/D ratio, MPO activity, and lung ICAM-1 mRNA expression compared with the control group(P＜0.05). Precondition with 2.4% sevoflurane significantly attenuated the above mentioned changes induced by LPS (P＜0.05). The 3.6% LPS (Group C) significantly attenuated lung tissue damage and decreased MPO activity,lung ICAM-1 mRNA expression compared with the Group F (P＜0.05),but no significant change in lung W/D ratio was seen (P＞0.05). MPO activity was significantly decreased in Group E (P＜0.05), but lung W/D ratio and lung ICAM- 1 mRNA expression had no significant changes (P＞0.05).Conclusion Precondition with 2.4% sevoflurane can reduce LPS induced lung injury in rats. Decreased expression of ICAM-1 and less accumulation of neutrophils were participated in its mechanism.

Objective To investigate the effectiveness of background music in operating room on psychology of patients and medical personnels. Methods A total of 127 patients who would receive selective operation and 65 surgical staff in our hospital were randomly divided into the intervention group and the control group. There were 63 patients and 30 medical personnel in the intervention group, 64 patients and 35 medical personnel in the control group. Routine care was given to all patients, and background music was broadcasted after patients and medical personnels coming into operating room in the intervention group. The blood pressure and heart rate of patients were contrasted, and the anxiety status was evaluated by Self-Rating Anxiety Scales (SAS), Visual Analogue Scale was used to appraise the horror, discomfort and pain between the control group and the intervention group. Results Diastolic pressure and systolic pressure was higher and heart rate was more rapid in the control group than in the intervention group. SAS score of patients and medical personnel was higher in the control group than in the intervention groups, degree of horror, pain and complaint in patients was more apparent in the control group than in the intervention group. Conclusions Background music could release negative emotion and was helpful for stabling the mood of medical personnel and preserving physical and mental health of patients.

Adult ; Altitude ; Asian Continental Ancestry Group ; genetics ; Female ; Humans ; Janus Kinase 2 ; genetics ; Male ; Middle Aged ; Mutation ; Polycythemia ; diagnosis ; ethnology ; genetics

Aged ; Anthracosis ; physiopathology ; Humans ; Lung ; physiopathology ; Male ; Middle Aged ; Pulmonary Ventilation ; Respiratory Function Tests

Objective • To exploring effect of the online situated courses which were developed based on the six-step model of crisis intervention on improving the crisis intervention skills. Methods • A total of 118 learners were recruited to receive online course training to improve their crisis intervention skills. Two types of courses were prepared, which were situated interactive course and non-interactive course for situated group and control group respectively. The changes in crisis intervention skills were compared between the two groups of learners before and after learning. The effects of situated learning were evaluated comprehensively from diagnostic evaluation, formative evaluation and summative evaluation. Results • After learning, the scores of crisis intervention skills of both groups were significantly improved (Psituated=0.000, Pcontrol=0.002). And the improved score of crisis intervention skills of situated group was higher than that of control group (P=0.010). The results of comprehensive evaluation showed that the well-mastered crisis intervention skills were identifying problem, providing support and getting commitment, the scores of which were 31.52±4.43, 16.85±4.44 and 14.63±5.27, respectively. Conversely both confirming safety and formulating plan skills should be reinforced, the scores of which were 10.26±3.93 and 5.84±4.10, respectively. Conclusion • The online course has a significant effect on improving the crisis intervention skills of learners, and the situated interactive course is more effective than the non-interactive course.

Objective: To explore the application of sequential pattern mining to the field of mental health, and analyze the role of the courses in improving the crisis intervention skills of mental health service personnel. Methods: The learning log data recorded by the online learning platform was used for sequential pattern mining, and the activity map was used to visually analyze the learning paths of learners with different learning performances. Results: In each case study, the number of high-frequency sequences of learners with different learning performance had significant differences, which were high-performance group > medium-performance group > low-performance group. In the crisis intervention consultation learning process, the high-performance group learners had the most diverse learning paths; the medium-performance group lacked the mastery of the several specific steps of the six-step model of crisis intervention, and the learning path integrity was poor; the low-performance group did not have a complete learning path. Conclusion: Diversified crisis intervention strategies are conducive to the smooth progress of the consultation process. Learners with different learning performance should develop corresponding skills development strategies according to their learning characteristics.

Objective:To explore the effect of emotional intelligence on the behavioral performance in crisis intervention, taking the knowledge and skills learning performance of crisis intervention as the mediating variable. Methods:Based on the sequential pattern analysis and comprehensive evaluation of learning performance in the previous study, Emotional Intelligence Scale was used to collect the emotional intelligence of 104 mental health service personnel. The mediating effect model was used to analyze the relationship among personal traits, learning performance and behavior performance. Results:There was no direct correlation between emotional intelligence and behavior performance (r=-0.016, P=0.869). The knowledge and skills learning performance of crisis intervention in identifying problems, providing support and coping strategy played a complete mediating role between emotional intelligence and behavior, with indirect effects of a1b1=-0.052 (P=0.010, 95% CI -0.126 - -0.010), a2b2=0.139 (P=0.000, 95% CI 0.063 - 0.259), and a3b3=0.087 (P=0.012, 95% CI 0.019 - 0.186). Conclusion:Emotional intelligence interferes in behavioral pattern by affecting crisis intervention learning performance, but influence relationships are inconsistent.