Objective: To investigate the understanding of other' s mind in children with autism in Beijing.Method: The instrument of this study was experimental test story. Results: Children with autism could understand other person' s physical and social desire, and predict behavior of others in accordance with desires. They basically unerstood other' s positive and negative emotions. However, they had a special difficult in understanding other' s cognitive mental states such as false belief. Concluslon: It indicated that the development of understanding other' s mental state is much more gradual and complex. Understandding other' s false belief is not all or nothing. The difference in understanding other's false belief between children with autism is not absolute, but relative.

Humans ; Infant, Newborn ; Infant, Newborn, Diseases ; Lupus Erythematosus, Systemic

End stage liver disease is a serious threat to human health.Existing conventional therapies are far from ideal,and orthotopic liver transplantation is limited by the lack of donor liver.A new therapy,transplantation of hepatic stem cell,is a promising approach.Hepatic oval cells are hepatic stem/progenitor cells(HSC/HPC)during hepatic regeneration,and they are being referred to as hepatic precursor cells.It got its name because of its oval nucleus,high nuclear/cytoplasmic ratio and other morphological features.Research has shown increasingly importance in the knowledge of hepatic oval cells.There are many signaling pathways in hepatic oval cells activation and proliferation.As a branch of the Wnt signaling pathway,Wnt/β-catenin signaling pathway has a significant effect on hepatic oval cells activation and proliferation.However,the exact mechanisms of this process have not been completely elucidated.This review describes the role of Wnt/β-catenin signaling pathway in hepatic oval cell activation and proliferation.

Objective To assess the effects of very-low-carbohydrate diet (VLCD) on body function and body composition in obese or overweight subjects.Methods Thirty five overweight or obese subjects were enrolled in the study,including 10 males and 25 females with a mean age of (43 ± 10) years.All subjects received VLCD intervention and 30 min moderate-intensity exercise daily for 3 months.The height,weight,blood pressure,heart rate,blood lipids and body composition were measured before and 1,3 months after intervention.ANOVA or nonparametric test was used for statistical analysis.Results After 3-month intervention,compared to baseline,the average body weight was decreased by 17.2 and 5.9 kg,waist circumference was decreased by 15.1 and 4.5 cm,BMI index decreased by 4.3 and 3.4 kg/cm2,waist to hip ratio was decreased by 0.1 and 0.1,for males and females,respectively (F =11.65 and 5.28,8.36 and 3.73,9.28 and 12.06,3.32 and 19.43,all P ＜ 0.05).Compared with the baseline,the systolic pressure was decreased by 12.2 and 9.2 mmHg(1 mmHg =0.133 kPa),triglycerides were decreased by 0.25 and 0.42 mmol/L,fasting blood glucose was decreased by 0.13 and 0.43 mmol/L after 1 month and 3 months of intervention,respectively.The proportion of patients with fatty liver was decreased from 69％ (24/35) at baseline to 49％ (17/35) at 1 month after intervention and further to 6％ (2/32) at 3 months after intervention (x2 =27.52,P ＜ 0.05).Conclusion The results indicate that VLCD can effectively control the body weight,and significantly improve the state of body function disorder.

Chronic kidney disease(CKD) is a major global health issue that leads to end-stage renal disease which untreated.The use of stem cell therapy provides a new perspective in this area.Reviewing the experimental studies of stem cell therapy on CKD,many different,and even contradictory reports in this area were found.In this paper,the recent reports,and present several key issues of experimental stem cell treatment on CKD were reviewed,including the source of stem cell,the sort of experimental animal,the time of treatment and other experimental details.Hoping these may lead more understanding in this area.

OBJECTIVE To investigate the associated risk factors for the infected patients in respiratory intensive care unit(RICU) and to study the resistance of isolates.METHODS To study the bacterial spectrum and drug resistance test of all the patients with hospital acquired infection from Jan to Dec 2005.Identification and antimicrobial susceptibility were determined with the methods of API and K-B,respectively.RESULTS A total of 265 strains were isolated from 117 patients,the rate of isolation of Gram-negatives was the highest(74.3%),the species were predominated by Pseudomonas aeruginosa,Acinetobacter baumannii and Klebsiella pneumoniae,the rates of isolates were 28.68%,23.02% and 5.66%,respectively.The predominated species of Gram-positives was Staphylococcus aureus.Gram-negative bacilli were susceptible to imipenem and meropenem,there were not vancomycin-resistant strains.CONCLUSIONS It is important to realize the associated risk factors of infected patients in RICU and to promote the rational use of antimicrobial agents.

Objective To investigate the influence of all-round intervention on the quality of life and the emotion of cancer patients who have accepted the gamma knife therapy. Method Using health education, psychotherapy and the behavior treatment for 260 patients with malignant tumor who had accepted the gamma knife therapy. Evaluated the quality of life and the emotion of these patients before and after the intervention respectively by using questionnaire of QOL, SCL-90, SDS and SAS. Results The values of indicated the QOL, SCL-90, SDS and SAS before the all-round intervention were 23.12?4.68, 68.12?33.26, 40.12?10.28 and 42.48?12.16 respectively. The values which had obtained after the all-round intervention were 46.26?3.28, 36.12?26.23, 28.16?5.23 and 26.12 ?10.66 respectively, there were significant differences between them,P

Technologies for the trans-institutional sharing of scientific data were studied with the sharing of nucleic acid sequence data as the study object , such as leaving a flexible space for implementation of the unified standards in working out the criteria for data sharing , implementing regular point to point data sharing and updating in agree-ment of institutional league , and providing multiple data services according to the unified working process by giving considerations to the local demands .The significance of trans-institutional sharing of scientific data under the insti-tutional league model was summarized for the reference in constructing the scientific datasharing platform.