Objective To explore the antimicrobial resistance of Moraxella Catarrhalis in children with respiratory infection.Methods Eleven strains of Moraxella Catarrhalis were isolated from nasopharyngeal secretion in 145 children with community-acquired respiratory tract infection in Beijing Friendship Hospital from 2004 to 2006.Segregated stocks were isolated from upper respiratory infection in 5 cases,bronchitis in 3 cases and pneumonia in 3 cases.Agar dilution method was used to determine minimal inhibition concentrations (MIC),including 8 kinds of antibiotics,and ?-lactamase was detected.WHONET 5 and SPSS 11.5 software were used to analyze data.Results Ten of the 11 strains were ?-lactamase positive.The rates of resistance to ampicillin,cefuroxime and erythromycin were 81.8%,63.6% and 18.2% respectively,however,all the strains were susceptible to ceftriaxone.MIC90 of penicillin and cefradine was 32.0 mg/L and 8.0 mg/L respectively.MIC90 of roxithromycin and azithromycin was 2.0 mg/L and 0.25 mg/L respectively.Conclusions Moraxella Catarrhalis is an opportunistic pathogen.The ?-lactamase positive rate of Moraxella Catarrhalis from children is high,and there is also a high resistance percen-tages of Moraxella Catarrhalis to penicillin,ampicillin,first and second generation cephalosporins.Moraxella Catarrhalis is susceptible to Cefuroxime.

〔Abstract〕 Taking PubReader as an example , the paper introduces typical applications of HTML 5 in displaying medical information . By cases in medical information display , it illustrates advantages of HTML 5 in interface alternation , intelligent terminal support , multime-dia presentation , and local storage , etc.It also predicts its future development tendency and disadvantages .

The paper takes the reports and conference proceedings discussed by domain experts during 2015-2016 International Biocu ration Conference and the research literatures about biocuration and data biocuration in PubMedCentral in recent 5 years as the data sources,analyzes,concludes and summarizes the research subject of biocuration through the content analysis method,and focuses on the sorting of working mechanism of biocuration,construction & application,integration & visualization,review and editing & application of biomedical data standards,mining of biomedical texts,in order to provide international experience for the development of biocuration in China.

After the current studies on mobile health in China and foreign countries were described, the mobile APP for health management of diabetes mellitus was developed using data mining technology, which can be used to assess the risk of diabetes mellitus, monitoring the symptoms and signs of diabetes mellitus patients, medication and diet management of diabetes mellitus patients, health-related knowledge push, and public health management.

Objective To investigate antirnierobial resistance of comlnon pathogenic bacteria isolated from children's respiratory tract in Beijng friendship Hospital during the period between January 2004 and December 2006.Methods Forty-nine strains of Streptococcus pneumoniae,fifty-five strains of Staphylococcus aureus and fifteen strains of Group A β-hemolytic streptococcus were isolated from children with community-acquired respiratory tract infeetion in pediatric department of Beijng Friendship Hospital.Kirby-Bauer agar dilution method Was used to determine the susceptibility to antimicrobial agents.Results Ninety percent of Streptococcus pneumoniae strains were resistant to erythromycin.Penicillin-non-susceptible streptococcus pneumoniae accounted for 10%,while 90% of which were multi-drug resistant.For Staphylococcus aureu strains,the resistant rates of ampicillin,penicillin and oxacfllin were 86%,82%,and 9% respectively,and serere multi-drug resistance was found.Eighty percent of the group A β-hemolytic streptococcus strains were resistant to erythromycin,however all remained sensitive to penicillin and ampicillin.Conclusion The antimicrobials resistant pathogenic bacteria isolated from children with respiratory tract infection have become a severe prdblem.The resistant rates of macrolides are high for Streptococcus and Group A β-hemolytic streptococcus.MeticiUin resistant staphylococcus aureus(MRSA)strains were found in the study.Severe multi-drug resistance was found.Non β-lactam antibiotics should be avoided when respiratory tract bacterial infection occurred in children.

Objective:To explore the mechanism of traditional Chinese medicine compound (Yang Yin Kang Du powder) in radioprotection.To study the relationship between T lymhocytes and antioxidation of mice radiated with X ray.Methods:T lymphocyte subset of in peripheral blood mice was determined by indirect immunofluorescence and flow cytometer.To T AOC,Cat,SOD and MDA were anoly zedby chemical colorimetry.Results:Compared with the normal group,the percentage of CD4 and CD8 in two irradiated groups declined significantly( P

The application , its related problems and advances in revising ICD in domestic hospitals were investiga-ted by on field and literature survey with strategies put forward for its construction in medical information institutions .

Objective To investigate the characteristics and possibility of using an image analyzer-aided method to count axotomized retinal ganglion cells (RGCs). Methods The left optic nerves of 18 rats were transected intraorbitally and a piece of gelform soaked in 5% fluorogold was applied to the ocular stump to retrogradely label the surviving RGCs. All animals were executed 2, 7 or 14 days after the operation (n=6 for each time point), respectively. The left retinae were removed, post-fixed and whole-mounted on the slides. The numbers of labeled RGCs were counted using both the conventional sampling method and image analysis, and compared statistically between the two methods. Results The number of surviving RGCs decreased sharply [(12 0663?9 089), (59 285?17 071) and (17 802?19 84) cells/mm 2 for image analyzer-aided method, and (118 237?7 898), (57 648?14 533) and (18 070?1 461) cells/mm 2 for conventional sampling method] when the survival time increased from 2 to 7 and 14 days. No significant difference was detected between the two groups at any corresponding time points. Conclusion The image analyzer-aided method is convenient, objective and reproducible, which can be used in the studies where counting RGCs is needed.

Objective As members of CNEDERT, we were trusted to take the mission of medical rescue in April of this year in Yushu area of Qinghai province. As soon as we heard of the news of earthquake with shock of 7.1 on Richter scale happened on 14th April 2010, our team of 32 members from the General Hospital of Armed Police Force rapidly rushed to get there at 19 o'clock on 14th April. It is a cold plateau with 4000 meters in average above sea level. Of course, they would face many difficult problems and some of them could not be figured out in advance. It was really a new and big challenge. First of all, we had to bear the very low barometric pressure,threatening lives of team members. In order to fulfill the mission of medical rescue, and to prevent the acute mountain sickness (AMS) ,we monitored the physiological changes of every member. Method A total of 32 members aged from 27 - 42 years old with average age of (33.26 + 12.54) years, 6 male and 6 female, gathered at Peking, 50 meters above sea level, 6 hours ahead of getting to Yushu and received physical examination with measurements of SaO2, HR, Hb and breath holding test. The team worked in Yushu area for 13 days and returned back to Peking on 27th April at 13 o'clock. The measurements of SaO2, HR and He were kept on from 14th April to 4th May, 21 days in total. The occurrence of AMS was surveyed by questionnaire from 18 to 48 hours after arrival,and the AMSA was diagnosed and scored according to the Lake Louise consensus on the definition and quantification of altitude illness. When the score was equal or above 3, it was considered to be AMS. Our work activities included searching the victims under the collapsed building, carrying out treatment and operation as soon as possible in the mobile hospital, doing medical round visiting, public health and disease prevention, work of joint rescue of multiple professions and psychological counseling. Results Of them 26 (81.25%) members suffered from AMS of various severities and few of them had pulmonary edema and hematuria, and those with SaO2 below 60% were sent down to the plain of low level above sea. The average level of SaO2 at Peking was ( 98.21 + 2.63) %, and it suddenly dropped to (66.31 ± 4.24)% on the first day of entering Yushu area, and from the 2nd day on, it gradually increased to (84.80 ± 4.20)% on the 13th day of stay in Yushu. On the 14th day, we returned back to Peking, the average SaO2 gradually went up from ( 85.57 + 2.73) % to (85.70 + 3.11 ) % on the 15th day,(87.93±2.63)% on the 17th day, (92.21 ±3.62)% on the 18th day, and (98.2333 ± 1.78)% On the 21st day (5th May ). At plain the average HR was (78 ± 11 ) beats/min, and it went up abruptly to ( 121 ± 18) beats/min on the first day of arrival to Yushu, and from the 2nd day on, it slowly lowered down to (99± 12) beats/min at the end day of stay in Yushu area. When we got back to Peking, the average HR gradually normalized from (91± 18) beats/min to (77 + 16) beats on the 5th May. The average Hb in Peking was ( 118 ± 32) g/L, and it gradually increased to ( 137 ± 18) g/L on the 5th day and to ( 161 ± 27) g/L on the 11th day after arrival, and it gradually dropped to (127:± 13) g/L on the 17th day and to (120± 13) g/L on the 21st day. Various measures were taken to treat and prevent the AMS with Chinese herbal medicines such as hongjingtian (Rholiola sacra [Prain ex Hamet] Fu), droplet-sized pill of danshen (salva miltiorrhiza Bge), slice of xiyangshen (Panax quinquefolium L)for lozenge which had some effect of minimizing the symptoms of AMS, and with easily digestible diet catered for in less amount of food in each meal and more meals every day, and diet was composed of mainly carbohydrate and vitamins. Large amount of fluid was required at least 4000 - 6000 mL daily guided by the number of urination at least once or twice a day. For the severe case with shortness of breath and sense of oppression over chest, the oxygen inhalation and intravenous glucose saline with small dose of hydrocortisone were given. Conclusions There were great changes in SaO2, HR and Hb of individuals rushed into high altitude area from plain of low level above sea in a short length of time. But those individuals had the capability of adaptation to ameliorate bit by bit those changes day by day until 13 days of stay, the end of stay at high altitude. On that day, the levels of SaO2, HR and He were still far away from normal. And those changes took 6 days to resume the original levels after the members retumed to the plain. Of them, 81.25% (26/32) members suffered from AMS of various severities. Various measures taken to treat and prevent the AMS are very important. In addition, working at high altitude area, the medical equipment and facilities should be miniaturized for easy portability on the rugged and narrow footpath in order to preserve the energy of medical members.

Objective To analyze the major adverse reactions of anti-hyperlipidemia drugs and their influencing factors.Methods The adverse reactions of anti-hyperlipidemia drugs in 579 patients were retrieved from the National Population and Health Scientific Data Platform.An adverse reaction-matched dictionary was established by normalizing the names of anti-hyperlipidemia drugs according to the drug name + dosage form and describing the adverse reactions according to the WHO adverse reaction terminology.The data set dimensions were analyzed by data mining.Results The adverse reaction rate of intravenous drip was 75.4% and manifested as chest distress,itching and dyspnea.The rate of adverse reaction involving organ systems was 61.1% and manifested as systemic injury,fever,discomfort and anorexia.Logistic regression analysis showed that the drug giving route was a factor influencing the severity of adverse reaction.Conclusion The adverse reactions of anti-hyperlipidemia drugs involve systemic,skin and its appendix injury.Drug giving route is the major factor influencing the severity of adverse reaction.