OBJECTIVE: To study the anti-lipid peroxidation action of Rosa davurica Pall. fruit. METHODS: The contents of malondialdehyde (MDA) of the tissue homogenate of the liver, heart, kidney, brain and of the red blood cells induced by hydrogen peroxide in mice were measured. The contents of MDA and the activities of superoxide dismutase (SOD) and glutathione peroxidase (GSH-Px) of ischemic myocardium of mice were measured. RESULTS: 0.2 g/L Rosa davurica Pall. fruit could decrease significantly the contents of MDA of the all tissue (P < 0.05). Inhibition rate of 6.7 g/L Rosa davurica Pall. fruit on MDA of the red blood cells induced by hydrogen peroxide was 89.2%. Administration of this extraction successively for six days (ig, 2.0 g x kg(-1) x d(-1)) can significantly reduce the content of MDA (P < 0.01) and augment the activities of SOD and GHS-Px (P < 0.05) in the ischemic myocardium of mice. CONCLUSION: Rosa davurica Pall. fruit can significantly prevent the lipid peroxidation.

Objective To evaluate the health-related quality of life in convalescents of severe acute respiratory syndrome.Methods Health-related quality of life evaluated by SF-36 scale was performed on 68 SARS patients discharged from hospital in the first and sixth month during 2003-05～2003-12 in Department of Respiratory Medicine of Beijing Friendship Hospital.Results In the first month,SARS patients had a significant impairment in both physical and psychological functioning.Physical condition improved significantly six months later,but there was no obvious improvement in mental health.Conclusion Psychological treatment should be included.The SF-36 scale is a valid,sensitive and reliable tool for assessing the quality of life for SARS patients.

Superoxide anion releasing from activated murine macrophages stimulated with recombinant human interferon-? (IFN-?), tumour necrosis factor-? (TNF-?) and bacterial lipopolysaccharidc were studied. The results showed that both of the cytokines enhanced superoxide anion release in a dose and time - dependent manner, but lipopolysaccharide had no such an effect as compared with IFN-? and TNF-?. It was also shown that O2- generation from macrophages was highly enhanced after primed with IFN-? or TNF-? for 24 hours. It was concluded from these data that cytokines released from macrophages and lymphocytes during inflammatory reactions could promote O2- generation which may play a crucial role in destruction or kill of intracellular pathogenic bacteria, and tumour cells.

Effects of Lycium barbarian polysaccharide (LBP), Astragalus polysaccharide (APS), polysaccharide of Acanthopanax senticosus (PAS) and polysaccharide of lipopolysaccharide (PS) on cytotoxicities of LAK cells from splenocytes of C57BL/6 mices were observed with 18 h 125IUdR release assay. Our study demonstrated that the polysaccharides alone were shown to induce no cytotoxicities. When combined with rIL-2, all of 4 kinds of the polysaccharides augrnented LAK activities in dose-dependent manner. The augmentations reached the maximum at 0.01-0.1 mg ? ml-1 LBP, 0.01 mg ? ml-1 APS and PAS, 0.01 mg ? ml-1 PS. They were found to increase LAK activities in short range of rIL-2 concentrations (250-1000U? ml-1). If the polysaccharides were used beyond the suitable concentrations, they were shown to inhibit LAK cell activities.

Percutaneous coronary intervention(PCI) is widely used in the treatment of coronary heart disease because of its tiny trauma,short treatment,rapid effect.However,if the patients after PCI can not effectively control the risk factors,their quality of life will be affected.In this paper,we review the study of self efficacy and quality of life in patients after PCI in recent years,thus to lay the foundation for the subsequent clinical care.

Objective To study the anti-ageing and antioxidation of polyphends of vitis amurensis Rupr(PVAR).Methods Forty senile male Wistar rats (20 months) were divided into 4 goups according rats′ weights:senile negtive control group(A), fed with basic forage;two senile PVAR groups(B and C),fed with basic forage inchuding 200 and 400 mg?kg~ -1 ?d~ -1 PVAR;senile positive control(D), fed with basic forage inchuding 200 mg?kg~ -1 ?d~ -1 melissic powder.After fed continuously for 8 weeks,the MDA contents in RBC-membrane, plasma and liver,sulfhydryl content in RBC-membrane, sialic acid content,activity of Na~+-K~+-ATPasc, fluidity of RBC-membrane,and activity of plasma GSH-Px in rats were detected.Results Compared with group A,the contents of MDA in groups B,C,and D decreased significantly(P

This paper explored effect of AF internal fixation system in reduction of lumbar vertebral fracture.AF internal fixation system acts fixation and reduction roles for most of spinal blowout fracture through spinal hyperextension or devise opening to reduce fracture blocks in vertebral canal or anterior vertebrae.In addition,it alleviates neural compression to some extent.The collapsed vertebral reduction is achieved by traction of anterior and posterior longitudinal ligaments as well as intervertebral annulus fibrosus;the physiologic curvature and vertebral height are restored.Moreover,the spinal stability is maintained.Early functional exercise can promote fracture healing and reduce complications.In treatment of lumbar vertebral fracture by AF internal fixation system,screw entry,reduction,traction,and fusion are completed based on host biomechanics,and biocompatibility of implant and host should be paid more attention.

Objective To discover the common characteristics of award winning medical and health science and technology achievements in Shandong province,and provide a useful reference for the Medical Science Research Management.Methods Statistical analysis was conducted on the 2014 Shandong provincial science and technology award winning projects of medical and health.Results The rate of award winning in Shandong Provincial Science and Technology Award in 2014 was 37.42％,and declared the results of medical and health category winner was 27.91％.While the winners percentage was 35.23％-58.59％ in surrounding eight provinces in the same year.In the awarding group,the innovation points,popularize and applying in scientific and technical achievements,patent for invention,professional inventions,authorized patents within 5 years,SCI publication and its number within 5 years in turn was 3.79,1.25,1.81,1.81,1.83,5.48 and 4.23,respectively.In contrast,the numbers in the non-awarding group was 3.36,0.81,0.86,0.99,0.93,3.40 and 2.76.Conclusions Shandong Provincial Science and Technology Award is very competitive to win and is more difficult for the medical and health class.It is helpful with an original innovation achievement,such as service in-ventions or SCI publications within 5 years.The focus of Medical Science Research Management should be made accordingly adaptation.

Objective To investigate the effects of desflurane on hemodynamics in aged patients.Methods Thirty ASA gradeⅠ Ⅱaged patients,scheduled for elective surgery,were studied. Anesthesia was induced with intravenous thiopentol,succinylcholine and fentanyl.After intubation coesophageal Doppler monitor was performed to measure CO,PV,HR,FTC,CVP,CI,MAP and SVR following inhalation of desflurane at 0 5MAC,1 0MAC,1 5MAC and 2 0MAC respectively.Results Compared with those before inhalation desflurane,MAP and SVR decreased more significantly at 1 0MAC,1 5MAC and 2 0MAC(P0 05),HR and FTC increased significantly at 1.0MAC,1.5MAC and 2.0MAC(P

Soil particles are very heterogeneous in microscopic scale, which is manifested the double-layer structure made of the soil organic matter and mineral matter. In this work, Fourier by transform infrared photoacoustic spectroscopy ( FTIR-PAS) combined with independent component analysis ( ICA) was utilized for in situ depth-profiling of the manmade complex film, in order to lay a foundation of in situ characterizing the heterogeneous soil organic-mineral complex. The complex film was composed of the PE preservative film and office adhesive tape. The moving velocity of infrared photoacoustic spectrometer was set to 0. 16 cm/s, 0. 32 cm/s and 0. 64 cm/s, respectively. Independent component analysis ( ICA ) was performed on the photoacoustic spectra of the heterogeneous complex film. Results showed that the depth-resolved information of the complex film could be derived by changing the moving velocity, and the estimated thickness of PE film was 5. 4-7. 6 μm, which was close to the actual thickness 7 ± 1 μm. Moverover, the spectral features of the polyethylene ( PE) preservative film and office adhesive tape were extracted from the photoacoustic spectra of the heterogeneous complex film by means of ICA. Depth profiling of complex film samples showed that FTIR-PAS could be used as a new analytical tool to study heterogeneous soils, especially soil organic-mineral complexes.