Objective To find the the clinical characteristics and clinical outcomes of Type Ⅱ diabetic patients with tuberculosis.Methods Treatment group was included 93 elderly type Ⅱ diabetic patients with tuberculosis;control group was included 50 of elderly patients with simple tuberculosis patients;and the clinical treatments were compared and analyzed.Results According to the index after the treatment,the treatment group was divided into three groups:good control group of 29 cases,ordinary control group of 41 cases,poor control group of 23 cases.The tuberculosis lesions improved absorption rate,the voids reduce rate,the sputum conversion rate of poor control group were significant different from control group(P ＜ 0.01).The tuberculosis lesions improved absorption rate,the voids reduce rate,the sputum conversion rate of good control group and ordinary control group were significant different from poor control group (P ＜ 0.05 or P ＜ 0.01).Conclusion The treatment of type Ⅱ diabetic patients with pulmonary tuberculosis in elderly patients is associated with the degree of diabetes control ; more stable control of blood sugar can promote tuberculosis anti-tuberculosis treatment.

Objective To compare the effect of gatifloxacin and levofloxacin for treating acute bacterial infection.Methods According to the digital table,228 patients with respiratory or urinary tract infections were randomly divided into group A and group B,114 cases in each group.Group A was given gatifloxacin 200mg,adding 5％ glucose injection 100ml intravenous drip injection twice daily; Group B was treated with levofloxacin 200mg,by adding 5％ glucose injection 100ml intravenous infusion twice daily.The treatment course lasted 7-14 days.The clincal effect,bacterial clearance rate and adverse reactions of the two groups were observed.Results The cure rate and total effective rate of group A was 68.4％,93.0％,respectively,which of group B was 66.7％,90.3％,respectively,the differences were statistically significant (x2 =0.184,0.213,all P ＞0.05).The bacterial clearance rate and bacterial drug sensitivity test sensitivity was 89.4％,78.8％,respectively,which of group B was 77.2％,70.3 ％,respectively,the differences were all statistically significant (x2 =4.812,4.236,all P ＜ 0.05).The incidence rate of adverse reactions of group A was 7.0％,which of group B was 6.1％,there was no statistically significant difference (x2 =0.672,P ＞0.05).Conclusion Gatifloxacin has better effect and lower adverse reactions in the treatment of acute bacterial respiratory or urinary tract infections,and there is no significant difference compared with levofloxacin treatment,and it is worthy of clinical application.

A number of common view from Chinese experts with regard to diagnosis and treatment of hemorrhagic and thrombotic diseases had been recently released by Chinese Medical Association,in which is of importance about some items and its clinical application of thrombosis and hemostasis tests which have a significant effect on the decision-making of clinical diagnosis and treatment.It will be discussed that diagnostic standard,the key to the question and strategies of solution which based the common view in laboratory diagnosis for several kinds of hemorrhagic and thrombotic diseases,and it is very useful to the experts working on laboratory diagnosis of hemorrhagic and thrombotic diseases.

Flow cytometric immunophenotyping (FCI) of hematolymphoid neoplasia is a high-complexity assay with proper medical indications,and it requires a hish-standardization in the choice of antibody panel,analysis and reports of the data.It is necessary to provide a specialized training and education for laboratory professionals who perform FCI for hematolymphoid neoplasitr.

Many platelet function tests can be used for monitoring antiplatelet drug for the prevention and treatment of thrombotic diseases.These monitoring tests may be chosen based on different antiplatelet drugs which include aspirin,clopidogrel and GP Ⅱ b/Ⅲ a antagonist.There is difference of the drug resistance which is validated by different platelet function tests,and the relation with clinical adverse events should be farther clarifled.

Objective:To express and purify paired immunoglobin-like type 2 receptor beta(PILR?) and prepare the polyclonal antibody against its protein.Methods: The PILR? cDNA was amplified from the total RNAs extracted from human peripheral blood cells by RT-PCR and was cloned into pET-32a vector.The vector harboring PILR? gene was then expressed in E.coli by IPTG induction and the product was purified by Ni~(2+)-NTA affinity chromatography.Polyclonal antibody was prepared by immunizing rabbits with the purified protein.The titer and specificity of the antibody were examined by ELISA and Western blot,respectively.Results: Highly purified PILR? protein(Mr 42 000) was obtained.The prepared polyclonal antibody was highly specific and had a titer of 110 000.Conclusion: PILR? gene is successfully cloned and the purified PILR? protein is expressed.Polyclonal antibody against PILR?(with high titer and specificity) is successfully obtained,which provides a basis for further study on PILR?.

This article reviewed the feature and the advances in the application of micellar electrokinetic capillary chromatography(MECC),an important mean of high performance capillary electrophoresis(HPCE),for the analysis of complicated component of medicine,.The analysis of multi-component of routine medicine,chiral drugs,illicit drugs,Chinese medicine,drug and its metabolites were introduced.

In this paper the followings are reviewed; 1) seal oil and it's processing method, fatty acids constitutents, quality standards, applications in food, pharmaceutical and cosmetic. 2) general components of seal meat, extraction of hemin, physiological functions of peptides and vasoactive substances in seal meat. 3) preparation and applications of male reproductive organs of seal as traditional Chinese medicine having invigorating Yang efficacy.

Objective: To determine Stachydrine hydrochloride in Chanfukang Granules by HPLC. Methods: The determination was performed by HPLC after the substance being extracted through strong acidic positive resinoid.Results: The average recovery was 99.05 with RSD of 1.65%.Conclusion: The method is accurate and provides a certain evidence for controlling the quality of Chanfukang Granules.

The pathological findings in 3 cases of liver transplantation in primary he-patocarcinoma were reported .Possible pathological causes such as the rejective reaction, necrosis of the liver, formation of the biliary sluge, infection and relapse of carcinoma were discussed.