Many platelet function tests can be used for monitoring antiplatelet drug for the prevention and treatment of thrombotic diseases.These monitoring tests may be chosen based on different antiplatelet drugs which include aspirin,clopidogrel and GP Ⅱ b/Ⅲ a antagonist.There is difference of the drug resistance which is validated by different platelet function tests,and the relation with clinical adverse events should be farther clarifled.

The laboratory diagnosis of peripheral blood cell morphology by manual light microscopy remains one of the major labor-intensive procedures at the present time.The development speed and clinical application of blood cell morphology have been restricted evidently as a result of the manual procedure and so on.A revolutionary change appears in the laboratory diagnosis of peripheral blood cell morphology because automated digital image analysis (ADIA) has grown rapidly in the last ten years.A development trend will be the laboratory diagnosis of peripheral blood cell morphology by ADIA in future,and which may replace a majority of morphologic examination by manual microscopy in the wake of the technique use in medical laboratory.

In this paper the followings are reviewed; 1) seal oil and it's processing method, fatty acids constitutents, quality standards, applications in food, pharmaceutical and cosmetic. 2) general components of seal meat, extraction of hemin, physiological functions of peptides and vasoactive substances in seal meat. 3) preparation and applications of male reproductive organs of seal as traditional Chinese medicine having invigorating Yang efficacy.

Objective To evaluate the effect of Guanmaining tablet in the treatment of acute coronary syndrome (ACS) and its intervention of brain natriuretic peptide (BNP),high sensitivity C reactive protein (hs-CRP) and carotid atherosclerotic plaque. Methods Totally 100 ACS patients were divided into observation group and control group (n=50 for each).Control group was received nitrates,angiotensin converting enzyme inhibitors and other conventional drugs,while observation group received Guanmaining tablet plus conventional drugs. Results The total efficiency of observation group was higher than control group (92.0％ vs. 66.0％,P＜0.01).No bleeding rate was observed more frequently in observation group compared with control group (84.0％ us.62.0％,P＜0.05).After 10 d treatment,the levels of BNP and hs-CRP of two groups were declined compared with before treatment (P＜0.01),and observation group decreased more significantly than control group ( P＜ 0.01). After 10 d treatment,the size of plaque plaque thickness and intima media thickness(IMT) were decreased,and observation group showed more obviously (P＜0.05).There were no adverse reaction in two groups. Conclusions Guanmaining tablet may be reliable effect in the treatment of ACS patients,through improving BNP and hs-CRP levels and inhibiting atheromatous plaque.

ObjectiveTo explore effective treatment for moderate and severe neonatal hypoxic-ischemic encephalopathy(HIE).Methods46 cases of moderate to severe HIE were randomly divided into two groups.Control group of 21 cases only accepted the HIE conventional treatment,treatment group,25 cases accepted the HIE conventional treatment and were also given brain protein hydrolyzate combined naloxone treatment,the efficacy of various clinical indicators of the two groups were compared.ResultsThe remarkable effective rate and the total effective rate of the treatment group were significantly higher ( all P ＜ 0.01 ).Consciousness recovery time,recovery time of the original ability,convulsions,muscle tension,recovery time,sucking ability,recovery time,hospital days of treatment group were significantly lower than the control group( P ＜ 0.05 or P ＜ 0.01 ).ConclusionThe effect of naloxone therapy for moderate to severe HIE is significant,and the therapy has high clinical value.

Flow cytometric immunophenotyping (FCI) of hematolymphoid neoplasia is a high-complexity assay with proper medical indications,and it requires a hish-standardization in the choice of antibody panel,analysis and reports of the data.It is necessary to provide a specialized training and education for laboratory professionals who perform FCI for hematolymphoid neoplasitr.

This article reviewed the feature and the advances in the application of micellar electrokinetic capillary chromatography(MECC),an important mean of high performance capillary electrophoresis(HPCE),for the analysis of complicated component of medicine,.The analysis of multi-component of routine medicine,chiral drugs,illicit drugs,Chinese medicine,drug and its metabolites were introduced.

OBJECTIVE:To probe into the reasons why there has been increase in the adverse drug reactions(ADRs)induced by traditional Chinese drugs.METHODS:The concept of ADRs induced by traditional Chinese drugs,the naming,the actual condition,and the statistical methods of ADRs induced by traditional Chinese drugs as well as the combined use of traditional Chinese drugs with western medicines were analyzed.RESULTS & CONCLUSION:The ADRs induced by traditional Chinese drugs were less than those induced by western medicines,which should be evaluated scientifically and objectively.We should tighten control on ADRs monitoring and improve our academic level to achieve a correct and rational administration of traditional Chinese drugs.

OBJECTIVE:To observe the Therapeutic effect of Man'gan decoction plus compound glycyrrhizin in the trea_ tment of chronic type B hepatitis.METHODS:46patients with chronic hepatitis B were randomly divided into treatment group and control group.The treatment group was treated with self-planned Man'gan decoction for6mo plus compound glycyrrhizin for3mo;the control group received6months'conventional therapy-diammonium glycyrrhizinate,vitamin and amino acid compound injection,etc.RESULTS:At the end of treatment,the hepatic function and hepatic fibrosis index levels of the treatment group were superior to the control group(P

Objective To compare the efficacy of different thyroidectomy surgery on postoperative quality of life in elderly patients with thyroid cancer.Methods 56 patients with thyroid cancer in the hospital from August 2011 to October 2014 were selected,and they were divided into observation group and control group according to the different methods of treatment.Patients in the observation group accepted small incision improvement while the control group accepted conventional thyroidectomy.The operation time,intra -operative blood loss,intra -operative blood transfusion,postoperative drainage,length of hospitalization period,complications occurring,VAS pain score and SF -36 score 1 month after treatment in two groups were recorded for statistical analysis.Results In the observation group,the operation time,intra -operative blood loss,intra -operative blood transfusion,postoperative drainage,length of hospitalization period were obviously lower than these in the control group,the difference was statistically significant (t =3.568,2.139,6.368,3.716,3.569,all P <0.05).The VAS pain score and SF -36 score in the observation group of (2.02 ±0.25)points and (77.21 ±8.13)points were obviously higher than these in the control group of (2.61 ±0.29)points and (43.46 ±5.63)points,the difference was statistically significant (t =3.867,4.568,all P <0.05).The rates of postoperative complication in the control group and the observation group were respectively 16.0% (4 /25 )and 35.5% (11 /31 ),the difference was statistically significant (χ2 =0.035,P <0.05 ). Conclusion Small incision improvement has a better curative effect with fewer complications and can improve quality of life for patients with thyroid cancer,thus it's worth popularization and application in clinic.