1.The relationship between the aged retirees' group's body mass index and relative cardiovascular diseases risk factors
Chinese Journal of Health Management 2008;2(1):27-29
Objective To study the relationship between the aged retirees' group's body mass index(BMI)distribution characteristics and relative cardiovascular diseases risk tactors.Methods One thousand three hundred and forty-three retirees in health medical examination were tested for systolic pressure, diastolic pressure,serum triglyceride,total cholesterol and fasting blood glucose.Groups with different BMI and different genders were tested for their mortality.Results The detective rates of BMI insufficiency,normal,overweight and obesity were 6.18%,51.67%,35.52%and 6.63%respectively.There was no statistic significance between different genders.The prevalence rates of hypertension,hyperlipidemia and diabetes mellitus(DM)were 46.09%,46.91%and 7.45%respectively.It showed that the prevalence rates of male hypertension and hyperlipidemia were significantly above those of the female's(P<0.05).As the BMI increased,hypertention,hyperlipidemia and DM rates increased too,and obviously increased in overweight group compared to normal BMI group(P<0.05).The detective rate of cardiovascular disease increased correspondingly with the increase of BMI.Conclusion BMI increasing is the important vascular relative risk factor for the aged retriee.
2.Clinical observation on therapeutic effect of Xiaoqinglong decoction for supplementary treatment of patients with ventilator associated pneumonia
Haiyun ZHU ; Jianying KAN ; Shuhua CAO
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2016;23(5):472-474
ObjectiveTo investigate the therapeutic effect of Xiaoqinglong decoction for supplementary treatment of patients with ventilator-associated pneumonia (VAP).Methods Thirty-three VAP patients with syndrome of traditional Chinese medicine (TCM) as interior retention of phlegm and exopathic cold admitted to Affiliated Hospital of Tianjin Academy of Traditional Chinese Medicine (TCM) from July 2011 to December 2014 were enrolled, and their historical data were retrospectively analyzed. According to the difference in treatment methods, the patients were divided into TCM treatment Xiaoqinglong decoction group (observation group, 18 cases) and general treatment group (control group, 15 cases). The patients in both groups were given conventional western medicine treatment, including anti-infection, phlegm elimination and cough relieve, protection of gastric mucosa and organ function, nutritional support, prevention of bedsore and thrombosis, etc. Additionally, the patients in TCM treatment group were given Xiaoqinglong decoction (drug composition: herba ephedrae 15 g, ramulus cinnamomi 15 g, herba asari 15 g, rhizoma zingiberis 15 g, chinese peony 15 g, rhizoma pinelliae 15 g, fructus schisandrae 15 g, radix glycyrrhizae preparata 10 g) for nasal feeding, once 150 mL, twice a day, once every 7 days. The changes in body temperature were observed before and 3 days and 7 days after treatment, and peripheral blood was collected for determination of white blood cell count (WBC) and C-reactive protein (CRP) level in the two groups. Comprehensive therapeutic effects of the patients in both groups were recorded.Results There were no significant differences in body temperature, WBC and CRP before treatment between the two groups. After treatment, the above parameters in both groups were significantly lower than those before treatment, and they showed a decrease tendency with time prolongation. The decrease in body temperature and WBC in observation group was more obvious than those of control group, and the comparisons showed statistical significant differences on 7 days after treatment [body temperature (℃): 36.5±0.6 vs. 37.0±0.8, WBC (×109/L):6.7±3.0 vs. 8.9±2.5, bothP < 0.05], but there was no significant difference in CRP between the observation group and control group (mg/L: 3 d was 73.7±20.5 vs. 61.5±18.4; 7 d was 27.2±10.5 vs. 23.5±9.1, bothP > 0.05). The total effective rate on the 7th day after treatment in observation group was higher than that of control group [83.3% (15/18) vs. 80.0% (12/15)], but no statistical significant difference was seen (P > 0.05).Conclusions The Xiaoqinglong decoction can reduce the inflammatory reaction of patients with VAP, and improve their symptoms.
3.Clinical Observation of Sertraline in the Treatment of Diabetes Patients Complicated with Depression
Guofang ZHU ; Yingying DONG ; Jianying XU
China Pharmacist 2015;(4):616-617,643
Objective:To investigate the effect and safety of sertraline tablets with oral administration in the diabetes patients com-plicated with depression. Methods:Totally 74 diabetes patients complicated with depression were randomly divided into 2 groups with 37 ones in each. All the patients were orally given dimethyldiguanide 500 mg,tid,and the observation group was given sertraline tablets additionally,50-100 mg,qd. The treatment course was 8 weeks. The changes of sugar metabolism and the scores of self-rating depres-sion scale( SDS)and quality of life scale( DMQLS)in the two groups were compared. Results:After the 8-week treatment,the blood sugar,SDS scores and DMQLS scores in the two groups were significantly improved when compared with those before the treatment( P<0. 05). The levels of FBG,2hPG and HbAlc and SDS scores in the observation group were significantly lower than those in the con-trol group(P<0. 05),while the scores of DMQLS disease,psychology,society and satisfaction dimension were significantly higher in the observation group(P<0. 05). The incidence of adverse reactions showed no statistically significant difference between the two groups(P>0. 05). Conclusion:Sertraline tablets can improve the depression of diabetes patients and enhance the blood sugar control and quality of life.
4.Comparison of clinical effects of butorphanol and flurbiprofen axetil combined with sufentanil on patients by controlled intravenous analgesia after the surgery of gynecological tumor
Xuqin ZHU ; Jianying TANG ; Yunkai CAO
China Oncology 2006;0(09):-
Background and purpose:It is important to control acute pain after gynecological oncologic surgery effectively.This study was to compare the clinical effects of butorphanol and flurbiprofen axetil(FA) combined with sufentanil on patient controlled intravenous analgesia(PCIA) after surgery.Methods:Forty ASA Ⅰ-Ⅱ patients scheduled for elective gynecological oncologic surgery under general anesthesia were randomly divided into two groups of twenty each,butorphanol group(Group B) and flurbiprofen axetil(FA) combined with sufentanil group(Group FS).After induction Group B received a loading dose of butorphanol 1 mg,and Group FS received that of FA 50 mg.Before the operation was over,Group B received intravenous infusion of butorphanol 13 mg in 100 mL saline,whereas Group FS received that of FA 150 mg combined with sufentanil 200 ?g in 100 mL saline.In the postoperative period,visual analogue scale(VAS),Ramsay sedative scores and side effects were recorded at 6,12,24 and 48 h.Results:There were not any signifi cant differences in VAS and the demanding times for supplemental bolus between the two groups.All VAS were below 4.Ramsay sedative scores of Group B before 12 h were signifi cantly higher than those in group FS(P0.05).The incidence of nausea and vomiting in Group FS was signif icantly higher than that in Group B(P
5.The correlation of father involvement with social adaptation of preschool children
Zhiwei ZHU ; Weijun CHEN ; Li ZHU ; Lin XU ; Jianying ZHAN
Chinese Journal of Behavioral Medicine and Brain Science 2011;20(9):853-855
Objective To investigate the correlation of father involvement with early social adaptation behaviors.Methods With social adaptation scale for infant-junior middle school' s student and a self-made questionnaire,1246 normal children,age from 16 to 72 months,were investigated.Regression analysis was performed to get the correlation of social adaptation with time and activities of father involved.Results After controlling for mother-,child- and family-related factors,the regression analysis showed that standard score of social adaptation was positively rehted with the time of father involved ( β =0.05,P=0.03 ),the time father invloved explain 12%of the variation of social adaptation.The father-child activities were related with social adaptation behavior,playing was related with work skills (β =0.09,P<0.01 ) and socialization ( β =0.06,P<0.05),story listening related with communication ( β =0.07,P < 0.05) and self-management ( β =0.06,P < 0.05 ),other activities related with self-dependence ( β =0.07,P<0.05) and work skills ( β =0.06,P<0.05).Conclusion The time and activities of father involved are related with children' s social adaptation.The effect of father involvement on early social adaptation is positive.
6.Effects of breathing exercise on preoperative pulmonary function in adolescent scoliosis patients
Jianying ZHU ; Wenqin YE ; Ke GONG ; Wenjun HAN
Chinese Journal of Tissue Engineering Research 2005;9(7):232-233
BACKGROUND: Acute respiratory insufficiency is common complication of surgical treatment of adolescent scoliosis patients. The preventive effects of breathing exercise before surgery is still uncertain.OBJECTIVE: To explore the feasibility and efficacy of breathing exercises for scoliosis patients before operation.DESIGN: Nonrandomized cross sectional study.SETTING, PARTICIPANTS and METHODS: Totally 35 hospitalized kids with scoliosis and pulmonary dysfunction aged from 9 to 15 years old were selected from Shanghai Changhai Hospital. A set of breathing exercise including which included pursed lip breathing, abdominal breathing, diaphragmatic breathing and blowing balloon was performed to these patients one week before surgery. The changes of pulmonary function were recorded and compared before and after exercises.MAIN OUTCOME MEASURES: The change of vital capacity, lung capacity, forced ventilation capacity(FVC), maximal ventilation volume(MVV) before and after breath exercises.RESULTS: All sorts of indes are improved comparing with those before exercises. The vital capacity, lung capacity, FVC and MVV were greatly improved from(1.77 ±0. 36), (2.67 ±0. 84), (2.07 ±0.46), (52.5 ± 14.0) L before exercises to(2.65 ±0. 29), (3.56 ±0.79), (2.41 ±0.41), (70. 1 ± 17.0) L respectively( t = 3.63 - 11.28, P < 0.01).CONCLUSION: Preoperative breathing exercises can improve the pulmonary functions of kids with scoliosis and improve their tolerance to surgery and prevent the postoperative respiratory insufficiency.
7.HEME EXTRACT AND ITS ENRICHED FOOD
Jun ZHU ; Jianying SHEN ; Tingchao YANG ; Chengmin ZHANG
Acta Nutrimenta Sinica 1956;0(01):-
Heme was extracted from fresh pig blood and made into powder in black coffee color. The product contained about 1.2%-1.8% iron and was added into food to raise its iron content.Three experiments were performed on young mice, piglets and anemic children. After feeding this product, their hemoglobin was all raised significantly (P
8.Surgical approaches for maxillary sinus cyst
Jianying HAO ; Hong KONG ; Dongdong ZHU ; Cuida MENG
Chinese Archives of Otolaryngology-Head and Neck Surgery 2006;0(01):-
OBJECTIVE To investigate the surgical approaches for maxillary sinus cyst. METHODS A total of 32 patients with maxillary sinus cyst underwent operation for removal the cysts. Among them, 8 patients with maxillary sinus cyst and sinusitis were operated on through Messerklinger approach, 19 patients with maxillary cyst received modified Caldwell-Luc operation under nasal endoscope and 5 patients received endoscopic removal of maxillary cyst through the maxillary sinus antrostomy at the inferior nasal meatus. RESULTS All the patients were followed up for 6 months to one year. There was no recurrence found in patients received modified Caldwell-Luc operation. There were 2 patients recurred in 8 patients who were operated on through Messerklinger approach and one patient had closure of the maxillary sinus ostium and adhesion of nasal cavity. One patient recurred and 2 lost follow up in 5 patients who received endoscopic removal of maxillary cyst through the maxillary sinus antrostomy at the inferior nasal meatus. CONCLUSION The optimal surgical method for maxillary cyst is modified Caldwell-Luc operation under nasal endoscope. Messerklinger technique may suitable for patients with complicated sinusitis.
9.Analysis and countermeasure research on configuration of orthopedic nursing manpower resource in grade-Ⅲ general hospital in Shanghai
Cui LIU ; Jianying ZHU ; Fengping LI ; Wenqin YE
Chinese Journal of Practical Nursing 2010;26(25):62-64
Objective To understand and analyze the situation of orthopedic nursing manpower resources in grade- Ⅲ general hospital in Shanghai and provide empirical evidence for appropriate allocation and exploitation of nursing manpower resources. Methods Data were collected by questionnaire and then underwent analysis. Results In 2009,the number of authorized beds was 1866,the actual number of open beds was 2007.The number of nurses was 595 (2 male).The ratio of ward bed and nurse were 1:0.319 and 1:0.296, calculated by the authorized beds and authorized beds, respectively.The average age of head nurses was (37.53±6.11 ) years old, average working life span was (17.87 ± 6.16) years; college degree or above accounted for 95.56%; middle professional titles accounted for 62.22%. College degree or above accounted for 75.13% in nurses, junior professional titles accounted for 92.1%; age group is mostly concentrated in the 20 to 29 years of age, accounted for 67.06%; working life span concentrated within 10 years, accounted foi 73.11%. The education level mainly is primary school in the care workers (carer), accounted for 45.83%; concentrated in the 40 to 49 years of age, accounted for 60.42%; working life span concentrated in more than 6 years, accounted for 55.21%. Conclusions There are shortage of orthopedic nursing manpower resources, unreasonable allocated structure, lack of male nurses in grade- Ⅲ general hospital in Shanghai. The management of the care workers should be standardized.
10.Exendin-4 stimulates ?-cell proliferation by up-regulating pdx-1 mRNA in STZ-treated mice
Min ZHU ; Hongli SHI ; Jinchong FANG ; Jianying SHI ; Kuixiang HUANG ;
Chinese Journal of Endocrinology and Metabolism 2000;0(06):-
0.05],butwaslowerthanthatof STZ group [(9.59?1.08)mmol/L, P