Objective To analyze the efficacy and safety of losartan in the treatment of massive proteinuria in kidney transplant recipients.Methods All of the 82 patients were randomized in two groups:losartan group and control group(amlodipine group).Both of the groups were divided into two different subsets according to blood pressure control Twenty-four-hour proteinuria,serum creatinine,blood pressure and adverse effects were observed.Results Losartan and amlodipine had the similar effects on blood pressure control The 24-h proteinuria in losartan group at the end of the study was significantly lower than that at the baseline,and there was significant difference between the losartan blood pressure control subset and the losartan blood pressure un-control subseL The effective rate and significant effective rate in losartan group for massive proteinuria were higher than in control group.Conclusion T Losartan can be effectively and safely used for the treatment of massive proteinuria in renal transplant recipients independent of blood pressure.

Mounting evidence indicates that oral health during pregnancy is associated with pregnancy outcomes and the oral health of the offspring. Pregnant women in China have a high prevalence of oral diseases, low attendance to oral health care, and an increased burden of untreated oral infectious diseases such as periodontitis and caries. A joint perinatal oral health program between obstetrics and stomatology may improve pregnant women's and their children's oral health outcomes. This paper briefly summarizes the current status of oral health care for pregnant women and the clinical practice in obstetrics and gynecology related to stomatology in China. It provides future perspectives on the potential role of obstetricians and gynecologists in promoting oral health care through developing an interdisciplinary care model.