Objective The levels of endothelin-1(ET-1) and calcitonin gene-related peptide(CGRP) in the plasma and cerebrospinal fluid(CSF)after acute cervical spinal cord injury. Method ET-1 and CGRP were determined by RIA in order to observe the effects of naloxone on levels of ET-1 and CGRP and neuronal death of cervical spinal cord. Result Levels of ET-1 in the plasma and cerebrospinal fluid(CSF)after acute cerical spinal cord injury increased significantly; but the levels of CGRP in the plasma and cerebrospinal fluid(CSF) decreased markedly. The levels of ET-1 in the plasma and cerebropinal fluid(CSF)decreased markedly after the threapy of naloxone; but levels of CGRP in the plama and cerebrospinal fluid(CSF)increased sinificantly. Conclusion These deta suggest that the lessening of CGRP and increasing of ET-1 may be some important reson causing death of neuron after acute cervical spinal cord injury, and naloxone can protecet cervical spinal cord neuron by increasing levels of CGRP and decreasing levels of ET-1.

Objective To investigate the safety and feasibility of laparoscopic pancreaticoduodenectomy (LPD). Methods Clinical data of 9 patients who underwent LPD operation from September 2014 to February 2017 in the first hospital of Shanxi Medical University were analyzed retrospectively. Results 9 patients attempted LPD, while one required conversation to open procedure. Two cases underwent hand assisted laparoscopic surgery .The average operative time was (553 ± 86.1) minutes, the average amount of bleeding was (333.3 ± 304.1) ml, and the average hospitalization time after operation was (25.3 ± 8.9) d. Postoperative bowel sound recovery time was (3.5 ± 1) d. Postoperative complications included pancreatic leakage in 4 cases (A grade pancreatic leakage in 1 cases, B grade in 3 case), lymph leakage in 1 case, abdominal hemorrhage in 1 case , gastric emptying in 2 cases , and bile leakage in 1 case. All patients with postoperative complications were cured by non operative treatment. Postoperative pathological examination showed that 5 cases had duodenal papillary adenocarcinoma, 1 case had pancreatic ductal carcinoma, 2 cases had common bile duct disruption differentiation of carcinoma, and 1 case had pancreatic head retention cyst. Patients were followed up 3 to 24 months after operation. 1 case of pancreatic duct died 17 months after operation. One case of middle bile duct carcinoma 12 months after surgery had liver and retroperitoneal lymph node metastasis. The remaining 7 cases had no complications. Conclusions laparoscopic pancreaticoduodenectomy is minimally invasive, safe and feasible.

0.05). Angiographically identified stent thrombosis occurred in 2 patients (0.9%) in Firebird group, 2 patients (0.9%) in Cypher group and 3 patients (1.6%) in Taxus group. Conclusion Implantation of the Firebird stent in unselected patients with coronary artery disease is safe and has shown no inferiority in one-year clinical outcomes compared to the Cypher or Taxus stents.

150?mol/L who underwent PTCA and/or coronary stenting were included (renal dysfunction group). Another 25 age and sex matched patients who had normal serum creatinine level and received coronary intervention at the same period were served as a control group. The status of coronary disease, procedural complications and long term prognosis were compared between the two groups. Results The number of patients with multi vessel disease (72% vs 48%, P

Objective To evaluate the feasibility, safety and efficacy of ACS MULTI LINK PENTA (PENTA) stent in patients with coronary artery disease.Methods From March to June 2002, thirty PENTA stents were implanted in 28 patients with 30 de novo lesions. For each patient the demographic, interventional and mean 3 month follow up informations were recorded. Results Almost two thirds of patients suffered from hypertension(61%) and half experienced unstable angina (53%). Most target lesions(67%) had unfavorable morphological characteristics (type B2 or C). No stent deployment failure occurred as well as acute or subacute stent thromobis.The major branches compromised after stenting were only in 2 patients. During floow up,no MACE occurred, except reoccurrence of chest pain in 2 patients (7%). Conclusions The PENTA stent appears to be safe and effective in treating coronary artery disease.

Objective To evaluate coronary flow reserve (CFR) in patients with myocardial bridging.Methods Between September 2000 and January 2003, thirteen patients were detected myocardial bridging(MB) by coronary angiography(MB group). Another 32 patients with normal coronary arteries were served as a control group. Demographic information and CFR were compared between the two groups. Results All patients in MB group were presented with stable angina pectoris, and the systolic and diastolic coronary compressing stenosis were 78%?7% and 15%?5%, respectively. CFR in MB patients was significantly lower compared with the controls(2.0?0.3 vs 3.3?0.6, P

Objective To assess the influence on

Objective To assess

Objective To evaluate the long-term effect of coronary stenting in young coronary artery diseased patients (45) undergoing coronary stenting were chosen randomly as the control group. Comparison the general characteristics, coronary angiographies, interventional and follow-up informations between the two groups was undertaken. Results Comparing with the control group, the young group patients presented much more myocardial infarctions (68% vs 35%, P

Objective To investigate the incidence,etiology and risk factors of cardiorespiratory arrest (CRA) in pediatric emergency room and preliminarily evaluate the efficacy of cardiopulmonary resuscitation (CPR).Methods The unified,standard in-hospital Utstein style was used for data collection with filling answers in the questionnaire.The survey items included the causes of cardiorespiratory arrest and the factors influencing the efficacy of CPR.The restoration of spontaneous circulation (ROSC) was used to evaluate short-term efficacy of CPR.Results Totally 182 380 patients aged from 28 days to 18 years were admitted to emergency room of Beijing Children' s Hospital between July 1,2008 and February 28,2010.Of them,237 patients (0.13％) were subjected to cardiorespiratory arrest,of which 169 patients received CPR and 88 patients (52.1％) got sustained ROSC.Neither sex nor age distribution affected ROSC.The primary cause of CRA and kind of initial abnormal rhythm of heartbeat leading to CRA were associated with the rate of ROSC.The rates of ROSC occurred in patients with or without pre-hospital transport were 64.1％ and 44.8％,respectively.The rate of ROSC was closely related to time consumed for getting ROSC by CPR,and as CPR durations were ≤ 10 min,10 to 30 min,and ＞ 30 min,the rates of ROSC were 67.5％,61.4％ and 30.5％,respectively.Multiple stepwise logistic regression analysis showed that kind of initial abnormal rhythm and CPR duration were associated with the rate of ROSC.Conclusions The incidence of CRA in emergency was 0.13％,and the rate of ROSC after CPR was 52.1％.The kind of initial abnormal rhythm of heartbeat and CPR duration were independent factors associated with the rate of ROSC.