1.Professor LIAN Jianwei's Experience in Treating Chronic DIarrhea
Journal of Zhejiang Chinese Medical University 2017;41(2):133-135
[Objective]Summarize the clinical experience of famous veteran doctor LIAN Jianwei in treating chronic diarrhea. [Methods] With the method of following Professor LIAN, analyse and induce his experience in treating chronic diarrhea by collecting cases. [Results] Professor LIAN is good at using classical prescriptions and current prescriptions to treat chronic diarrhea. According to the characteristics of diarrhea, to identify the viscera, cold and heat, asthenia and sthenia and flexible combination of prescriptions. Weakness of the spleen and the stomach using Shenling Baizhu Powder to nourish qi to invigorate spleen;Patients of liver stagnation and spleen deficiency are treated by Tongxieyao Formula to repress liver and supporting spleen;Sishen pill and decoction of four mild drugs treatment of spleen and kidney yang-deficiency by invigorating spleen and kidney;Patients of coldheat complex are treated by Wumei Pill to warm and nourish the stomach. [Conclusion] Professor's experience in treating chronic diarrhea is well worth learning for it always gets outstanding effect.
2.Effect of SR carbohydrate system on glucose and lipid metabolism in the elder patients with type 2 diabetes
Weijia HAN ; Jianqin SUN ; Qing YANG ; Xiafei CHEN
Parenteral & Enteral Nutrition 2004;0(06):-
Objective:To investigate the effects of slowly release(SR) carbohydrate system on glucose and lipide metabolism in the elder patients with type 2 diabetes. Methods:The previous enteral nutrition was replaced totally or partially with Glucerna in 11 cases of elder patients with type 2 diabetes for 1-3 months.The changes in hemoglobin, lymphocyte counts, serum albumin, total protein, glycemia, postprandial 2 hours blood glucose,glycosylated hemoglobin, triglyceride, cholesterol, kidney function,electrolytes and the symptoms of gastrointestinal tract were observed. Result:Total protein(P
3.Application of enteral nutrition support with different doses of glutamine in elderly critically ill patients
Weijia HAN ; Jianqin SUN ; Ruiping HAN ; Yiqian WANG ; Qing YI ; Li HUA ; Fang TIAN
Chinese Journal of Clinical Nutrition 2014;22(3):149-153
Objective To investigate the effects of enteral nutrition support with different doses of glutamine on nutritional status and gastrointestinal function in elderly critically ill patients.Methods Totally 90 critically ill patients were randomly divided into three group:the control group without glutamine (group A),enteral nutrition with low glutamine [0.3 g/(kg· d)] (group B),and high glutamine [0.6 g/(kg· d)] groups (group C).Fasting blood samples were collected on days 1,7,and 14 after the initiation of study,and then the indicators including serum diamine oxidase,glutamine,transferin (TF),prealbumin (PA),hemoglobin (HGB),albunin,and nitrogen balance were determined.In addition,the gastrointestinal complications including bloating,diarrhea,and gastric retention were recorded.Results On the 7th and 14th days,the serum glutamine levels in groups B and C were (1 886.8 ±420.5),(2 228.6 ±440.2) μg/L;(1 889.6 ± 436.1),(2 174.3 ± 440.8) μg/L,respectively,which were significantly higher than those in group A [(1 612.0 ±493.5),(1 869.7 ±559.8) μg/L] (P =0.027,P =0.008).The serum diamine oxidase levels were also significantly lower in group B [(2 310 ± 1 271),(1 602.5 ± 1 137.9) U/L] and group C [(2 076.3 ±567),(1 586.3 ±530.9) U/L] than in group A [(3 250 ±923),(2 476 ±862) U/L] (P =0.000,P =0.000).The serum TF and PA levels were significantly increased on the 7th day (P =0.023,P =0.047),and the HGB was significantly higher on 14th day (P =0.003),The number of patients who had undergone successful implementation of enteral nutrition were 4 and 3 in groups B and C,and the number of patients who had achieved the target volume of enterral nutrition was 25 and 27 in groups B and C,which were significantly larger than those in group A (12 and 13,respectively) (P =0.008,P =0.000).The gastrointestinal complication was also significantly decreased after the administration of enterral nutrition with glutamine.Conclusions Enteral nutrition with glutamine can improve intestinal mueosa barrier and nutritional status in elderly critically ill patients.Thus,it helps to reduce gastrointestinal complications and transition time of total enteral nutrition.
4.Second victims of medical adverse events: research and enlightenment on current situation at home and abroad
Chinese Journal of Hospital Administration 2018;34(10):877-880
In medical adverse events, medical workers involved tend to become the second victims due to physical and mental injuries, next to the patient in question and his/her family. This article introduced second victim from the following perspectives of such victims: current situation and causes, traumatic experience, natural recovery process and supportive actions taken. These authors provided hospital management with suggestions on how to effective support such victims, in an effort to draw attention of the society to physical and mental health of the medical staff, and minimize injuries so incurred to such victims.
5.Effect of losartan and irbesartan on blood pressure and ISI in female hypertension patients complicated with hyperuricemia
Jianqin HAN ; Yehua XU ; Ping LUO ; Jidong LI ; Lijuan HE ; Li MA ; Xiyun WANG ; Xiaozhou WANG
Chinese Journal of Primary Medicine and Pharmacy 2019;26(5):518-522
Objective To compare the effects of losartan and irbesartan on blood pressure,blood uric acid,insulin sensitivity and insulin resistance in female hypertensive patients complicated with hyperuricemia.Methods From August 2015 to December 2017,100 females of hypertension complicated with hyperuricemia who hospitalized in the Third People's Hospital of Ningxia were enrolled in the study.All the patients were divided into two groups according to the random digital table,with 50 cases in each group.The observation group was treated with losartan,and the control group was treated with irbesartan for 8 weeks.The total effective rate and adverse reactions were compared between the two groups.Also the changes of blood pressure,serum uric acid,fasting glucose (FBG),fasting insulin (FINS),high sensitivity C-reactive protein (hs-CRP),insulin sensitivity index (ISI) and insulin resistance index (HOMA-IR) were compared between the two groups after treatment.Results There was no statistically significant difference in the total effective rate between the two groups [92.0% (46/50) vs.90.0% (45/50)] (P > 0.05).Before treatment,there were no statistically significant differences in blood pressure,serum uric acid,FBG,FINS,hs-CRP,ISI and HOMA-IR between the two groups (all P > 0.05).After treatment,the systolic blood pressure and diastolic blood pressure in the two groups were (133.09 ± 10.11) mmHg vs.(131.54 ± 11.01) mmHg and (82.76 ± 6.23) mmHg vs.(83.75 ± 6.88) mmHg,which were lower than those before treatment (observation group:t =19.742,10.606,control group:t =18.925,-9.956,all P < 0.05).But there were no statistically significant differences between the two groups (all P > 0.05).After treatment,the serum uric acid in the observation group was lower than that in the control group [(387.21 ± 25.56) μmol/L vs.(429.67 ± 27.44) μmol/L] (t =8.006,P < 0.05).The hs-CRP,FINS,HOMA-IR,ISI in the observation group were (4.92 ± 1.02) rmg/L,(15.92 ± 3.01) mU/L,(1.71 ± 0.24),(1.047 ± 0.095),which in the control group were (4.54 ± 1.00) mg/L,(17.23 ± 3.20) mU/L,(1.65 ± 0.27),(1.140 ± 0.083).After treatment,the hs-CRP,FINS,HOMA-IR in the two groups were decreased (all P < 0.05),while ISI was increased (P < 0.05).Furthermore,the improvement of FINS,ISI and HOMA-IR in the observation group was better than those in the control group (t =2.109,-5.213,3.191,all P < 0.05).Conclusion Both losartan and irbesartan can improve clinical symptoms,lower blood pressure and improve insulin resistance in female hypertension patients complicated with hyperuricemia,and losartan is more effective than irbesartan.