1.Intervention of Electroacupuncture on Jianyu Acupoint to Rabbit Model with Scapulohumeral Periarthritis
Chenyao WANG ; Jianqiao FANG ; Xiaomei SHAO
Journal of Zhejiang Chinese Medical University 2006;0(04):-
[Objective]To observe the intervention of Electroacupuncture at Point Jianyu(LI15) on Rabbit Model of Scapulohumeral Periarthritis for receiving possible mechanism.[Methods ]Thirty healthy rabbits(male or female) were randomly divided into three groups:scapulohumeral periarthritis model group,EA Jianyu group and Ibuprofen control group.Each group respectively were detected the concentrations of serum PGE2 before model and treatment and after treatment,and then killed them to achieve tendons of shoulder which were detected the concentrations of Hydroxyproline.And achieve tissues around shoulder which were studied by HE to investigate the changes of the histology.[Results]The concentrations of serum PGE2 had no notable difference between EA Jianyu and model group,Ibuprofen control group and model group after treatment.But it was lowered after treatment than before treatment by EA Jianyu.There were no significantly difference among the three groups about concentrations of Hydroxyproline in tendons,but Ibuprofen control group was higher than EA Jianyu group.Tissues of the shoulder were observed that EA Jianyu restrained reaction of inflammation and degenerescence of tissues,and promoted it better.[Conclusions] EA Jianyu has anti-inflammatory effect and cuts back on the degree of degenerescence of tissues on scapulohumeral periarthritis model in rabbit.
2.Analysis of sub-health symptom and health risk behavior factors among left behind middle school students in Chongqing three-gorge area
Jianqiao LI ; Rui WU ; Hong WANG
Chongqing Medicine 2014;(29):3944-3947
Objective To study the sub-health status and health-risky behaviors of left behind middle school students in Chongqing Three-gorge area and provide the reference for targeted interventions .Methods 1 528 cases of left behind middle school students were collected from three middle school by multistage cluster random sampling in a reservoir of Chongqing ,surveyed with questionnaire about health-risky behaviors and Multidimensional Sub-health Questionnaire of Adolescents(MSQA) .Results The rates of psychosomatic sub-health symptoms were 45 .0% ,body sub-health symptoms detection rate was 23 .3% ,psychological sub-health symptoms detection rate was 40 .1% .Body energy insufficiency ,the physiological function ,decreased resistance detection rate were 10 .2% ,15 .1% and 12 .0% ,respectively .The emotional problems ,behavioral problems ,social adaptation difficulties detection rate were 25 .9% ,16 .8% ,34 .3% ,respectively .The symptoms of sub-health detection rate of boys was higher than that of girls (P>0 .05) ,the junior grade One was higher than the senior grade One(P<0 .05) ,the one-child was higher than non-only child(P>0 .05) ,the boarding students was significantly higher than the day students(P<0 .05) .Logistic regression analysis showed that the risk factors had unhealthy diet behavior ,deliberately harm behavior ,suicide behavior ,unintentional injury behavior and Internet addiction .Conclusion The sub-health problem of left behind middle school student in Chongqing three-gorge area is in a general level ,the relevant departments should take some targeted interventions to improve students'health level .
3.THE DESIGN OF THE REFORM ENGINEERING FOR HOSPITAL COMPUTER NETWORK SYSTEM
Jianqiao WANG ; Zhaosheng GAO ; Rongxing HUANG
Modern Hospital 2009;9(8):144-146
The construction of hospital informationization must rely on the basic computer network platform.Based on the practical engineering case and combined with the problems in the current hospital network system, this article provide a solution of reformation for the network structured cabling system and the network equipment.The idea of designing is also explored.
4.Clinical Study on Electroacupuncture in Mitigating the Symptoms Related to Menopausal Transition
Jing LIU ; Fang LIU ; Chao WANG ; Lifang CHEN ; Jianqiao FANG
Shanghai Journal of Acupuncture and Moxibustion 2016;35(7):839-843
Objective To observe and compare the regulating effect between electroacupuncture and sham electroacupuncture on the symptoms of menopausal transition and levels of estradiol (E2), follicle-stimulating hormone (FSH), and luteinizing hormone (LH), for evaluating the clinical efficacy of electroacupuncture in mitigating the relevant symptoms of menopausal transition. Method Thirty eligible subjects with menopausal transition were randomized into a treatment group and a control group, 15 cases in each group. The treatment group was intervened by electroacupuncture at the ordinary acupoints, while the control group was by electroacupuncture at non-meridian points. The E2, FSH, and LH contents were detected after intervention and at the 20th week during the follow-up study, the flush score and Menopause Rating Scale (MRS) were evaluated respectively after 4-week and 8-week treatment and at the 20th week and 32nd week during the follow-up study, and the safety of electroacupuncture was also estimated.Result The flush and MRS scores were significantly changed after 4-week and 8-week treatment and at the 20th week and 32nd week during the follow-up study in both groups compared to that before the treatment in the same group (P<0.01,P<0.05). There was a significant difference in comparing the changes of MRS score after 8-week treatment between the two groups (P<0.01). There were significant differences in comparing the changes of flushing scores between the two groups after 8-week treatment and at the 20th week and 32nd week during the follow-up study (P<0.01). The serum levels of E2, FSH, and LH were significantly changed in the treatment group after 8-week treatment (P<0.05). There were significant differences in comparing the changes of FSH and LH levels between the two groups after 8-week treatment (P<0.05). The difference in comparing the change of serum E2 level between the two groups at the 20th week during the follow-up study was statistically significant (P<0.05). Conclusion Electroacupuncture can improve the flushing intensity and produce a benign regulation on the relevant hormone levels in menopausal transition, though this regulation is insignificant when the treatment terminates.
5.Randomized Controlled Study on Acupoint Injection with BCG-polysaccharide Nucleic Acid for Bronchial Asthma
Lifang CHEN ; Luni CHEN ; Chao WANG ; Weirong FAN ; Jianqiao FANG
Shanghai Journal of Acupuncture and Moxibustion 2015;(6):500-502
Objective To evaluate the clinical efficacy of acupoint injection with BCG-polysaccharide nucleic acid (BCG-PSN) in treating bronchial asthma. Method Seventy-two patients with bronchial asthma were randomized into an acupoint injection group and a muscular injection group, 36 cases in each group. The acupoint injection group was intervened by acupoint injection with BCG-PSN to Zusanli (ST36) and Dingchuan (EX-B1) alternately, 1 mL for two points in total each time; the muscular injection group was intervened by muscular injection at the same dose and frequency, twice a week, for successive 3 months. The pulmonary function and asthma control test (ACT) were estimated before and after intervention and during March of the next year. Result After intervention, the FEV1 values were (80.97±2.31)% and (80.78±2.56)% respectively in the acupoint injection group and muscular injection group, and PEF values were (6.50±0.21)L/s and (6.48±0.25)L/s, and the between-group differences were statistically insignificant (P>0.05). The ACT score was (23.02±1.03) in the acupoint injection group, significantly better than (22.40±2.04) in the muscular injection group (P<0.05). The follow-up study showed that the ACT score in the acupoint injection group was superior to that in the muscular injection group (P<0.05). Conclusion Acupoint injection and muscular injection with BCG-PSN can equally improve the pulmonary function in bronchial asthma, while the acupoint injection can produce a more significant effect than muscular injection in improving ACT.
6.Exploration of Preponderant Electroacupuncture Parameters in Stage Treatment of Facial Neuritis
Jing SUN ; Chao WANG ; Lifang CHEN ; Jianqiao FANG
Shanghai Journal of Acupuncture and Moxibustion 2016;(1):101-104
Facial neuritis is clinically a common disease. Electroacupuncture has a positive effect on it and has been widely applied clinically, but how to select electroacupuncture waveform parameters, and whether and how to use electroacupuncture in the acute stage are still inconclusive. Through clinical practice and study, the authors found that the role of electroacupuncture was effectively played and the recover from the disease was quickened by combining the pathological characteristics of facial neuritis in different stages and adjusting the electroacupuncture protocol at a proper time. That is, during the acute stage when the disease is progressing, electroacupuncture is not used or used with sparse-dense waves for anti-inflammation and analgesia; during the convalescent stage, interrupted waves are used to excite the muscles and sparse waves are used to excite the motor neurons after the recovery of facial muscle excitability; during the sequela stage, sparse waves are used to maintain the therapeutic effect or dense waves to relieve facial spasm.
7.PPAR-γ:A New Target of Treatment for Inflammatory Reaction after Cerebral Ischemic by Acupuncture(review)
Zhe LIU ; Pei LIU ; Yong-wang ZHU ; Jianqiao FANG
Chinese Journal of Rehabilitation Theory and Practice 2008;14(12):1143-1145
The inflammatory reaction after acute cerebral infarction can aggravate the cerebral ischemic reperfusion injury.Activation of peroxisome proliferator-activated receptors-γ(PPAR-γ) has neuroprotective effects by which induces anti-inflammatory actions in cerebral ischaemia,thus as a potential novel pharmacological target for ischemic stroke was regarded.Acupuncture can improve cerebral ischemia injury by inhibiting synthesis of inflammatory cytokines,downregulating expressions of inflammatory mediators and adhesion molecule,suppressing the functions of inflammatory cells.Therefore,it will be a promising orientation to sift the effective acupuncture for that can stimulate the activation of PPAR-γ,and the research of mechanism of acupuncture on anti-inflammatory reaction after cerebral ischemic by activating PPAR-γ dependent pathways.
8.Functional evaluation of spleen T lymphocytes in the rat model of Walker-256 bone cancer pain
Junying DU ; Yi LIANG ; Yitian CHEN ; Saifei WU ; Hu WANG ; Junfan FANG ; Jianqiao FANG
Chinese Journal of Comparative Medicine 2014;(12):8-13
Objective To observe the functional changes of T lymphocytes in the spleen of rats with bone cancer pain.Methods forty-one healthy female Sprague-Dawley rats were used in this study, and were divided into blank control, PBS and Walker-256 tumor groups.Bone cancer pain model was established by inoculation of Walker 256 cancer cells into the tibial cavity.The paw withdrawal threshold (PWT), paw withdrawal thermal latency (PWL), and spontaneous pain (SP) were all measured before modelling (as base) and at 4, 6, 8, 10, 12, 14, 16, 18, and 20 days after modelling. The function of T lymphocyte proliferation, and the content of T lymphocytes and their subgroups in the spleen were detected by cell counting kit-8 method and flow cytometry, respectively, on day 20 after modelling.Results Before modellng, there were no differences of PWT, PWL, and SP between the PBS and model groups.After modelling, the PWT and SP of model group were significantly decreased on day 4, and were always lower than that of PBS group during the experiment.Statistical analysis revealed that Walker-256 cancer cell inoculation in the tibia induced a significant decrease in PWL on day 8, 10 and 12 after modellng.Compared with the control group, T lymphocyte proliferation, content of T lymphocyte (CD3) and subgroups ( CD4 and CD8) in the PBS group were not significantly decreased.However, T lymphocyte proliferation and the content of CD3 lymphocytes in the model group were significantly lower than those in the blank control group and/or PBS group.Conclusions The bone cancer pain rat model may appear obvious mechanical allodynia and spontaneous pain.Its thermal pain hyperalgesiaonly occurred in the intermediate stage of bone cancer pain. The content of T lymphocytes and its subgroups, and the function of T lymphocyte proliferation are weakened to some extent in the bone cancer pain rat model.
9.Advances in the Modern Studies of Acupuncture Treatment of Postoperative Ileus
Junfan FANG ; Junying DU ; Wen WANG ; Jinjin LI ; Xiaomei SHAO ; Jianqiao FANG
Shanghai Journal of Acupuncture and Moxibustion 2016;35(3):257-261
Postoperative ileus (POI) is a common abdominal postoperative complication of surgery as well as obstetrics and gynecology. There is a lack of an effective method of modern medicine due to its complex pathophysiological mechanism and the postoperative physiological disorder of patient. Acupuncture has remarkable regulatory effects on gastrointestinal function. Some clinical studies indicated that acupuncture was an effective method to treat POI, which could reduce the duration of POI and the treatment costs of patients in hospital. However, the mechanism and law of acupuncture on treating POI is still unclear. Some clinical studies indicated that the regulatory effect of acupuncture on the gastrointestinal motility was associated with its regulation of the autonomic nerve system and immune system. Based on its effect on regulating autonomic nerve system and immune system, acupuncture would be a potential and safe treatment for POI.
10.A prospective randomized controlled trial on effect of gastric volvulus early interference on incidence of pneumonia and prognosis of infants with cytomegalovirus infection cholestatic hepatopathy
Suqi YAN ; Lishan ZHOU ; Jianqiao TANG ; Hongyu ZHANG ; Wenbin ZHENG ; Fang WANG ; Yinghuai BI ; Jun LI
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care 2014;(4):249-253
Objective To study the effects of early application of integrated traditional Chinese medicine (TCM)and western medicine and massage on the incidence and severity of pneumonia and prognosis in the therapeutic course of infants with cytomegalovirus(CMV)infection infantile cholestatic hepatopathy(ICH)accompanied by gastric volvulus(GV). Methods A prospective randomized controlled trial was conducted. 120 infants 1-6 months old with CMV infection ICH and complicated with GV inpatients were divided into treatment group and control group (each,60 cases). The TCM Lidanheji(consisting of artemisiae capillaris 30 g,weeping forsythia 30 g,Chinese goldthread 5 g,prepared rhubarb 5 g,unpeeled root of herbaceous peony 30 g,cassia 5 g,fruit of citron or trifoliate orange 10 g,large-headed atractylodes 10 g,fruit of Chinese magnoliavine 10 g,pangolin scale 3 g and licorice root 5 g)for oral administration or enema and ganciclovir intravenous injection were given to both groups. In the control group,based on the above treatment,postural and diet therapy,prokinetics(domperidone)were given in cases with GV. The massage treatment was only applied for treatment of GV in treatment group. The pneumonia in both groups was treated in accord to the conventional diagnosis and treatment for infantile pneumonia,bronchiolitis,severe pneumonia and the guide and management of infantile community acquired pneumonia. The total number of cases with pneumonia and its severity occurring before and after treatment in the course of the disease,the clinical therapeutic effects of ICH, GV and infantile pneumonia,the clinical physical signs,biochemical indexes and the time of hospitalization were observed and compared between the two groups. Results Compared with control group,after treatment the curative rate and total effective rate of ICH,GV,infant pneumonia in treatment group were significantly higher〔the curative rate of ICH:83.05%(49/59)vs. 71.93%(41/57),total effective rate:96.61%(57/59)vs. 91.23%(52/57);the curative rate of GV:72.88%(43/59)vs. 51.79%(29/56),total effective rate:96.61%(57/59)vs. 78.57%(44/56);the curative rate of infant pneumonia:81.08%(30/37)vs. 67.44%(29/43),total effective rate:100%(37/37)vs. 100%(43/43),P<0.05 or P<0.01〕. In the treatment group,the total number of cases with pneumonia occurring in the therapeutic course and the incidence of severe pneumonia were significantly less than those in the control group〔the occurrence of pneumonia:12 cases vs. 21 cases,the incidence of severe pneumonia:16.67%(2/12) vs. 42.86%(9/21),P<0.05 or P<0.01〕. The enlargement of liver and spleen,the level of total bilirubin(TBil), direct bilirubin(DBil),total bile acids(TBA)and alanine aminotransferase(ALT)in two groups after treatment were significantly lower than those before treatment,the changes being more marked in treatment group(P<0.05 or P<0.01). The time of stay in hospital in treatment group was remarkably shortened(days:21.32±3.26 vs. 27.38±6.09, P<0.05). Conclusion Early interference with combined TCM and western medicine and massage for treatment of infants with CMV infection ICH accompanied by GV can significantly decrease the incidence of pneumonia and its severity occurring in the disease course,therefore this therapeutic method is beneficial to the treatment and prognosis of infants with CMV infection ICH.