Research on history of TCM should serve for development of TCM today.Researchers in history of prescriptions of Chinese materia medica should think the question about development of prescriptions of Chinese materia medica.Three problems about development of prescriptions of Chinese materia medica are brought forward currently.Firstly what is area of it in science,whether method of treatment and preparation are attached to it .Secondly whether classify of it is accordant to theory of TCM and method of treatment.Thirdly the Pharmacopoeia hold in the prescriptions .The items of Pharmacopoeia couldn’t satisfy clinical needs of TCM in processing and dosage.A standard of prescription should be drawn besides the Pharmacopoeia.

During the Qin-Han Dynasty,the system of terms of Traditional Chinese Medicine(TCM) has been initially established.With the progress of TCM subject and increasing of academic exchanges,one word having two or more meanings,one meaning with two or more words,and development of meanings of words have come into sight,following with the appearance of new concepts and terms.TCM terms have their distinction.The characteristics of TCM terms were: characteristic of history; ②characteristic of culture;qualitative description;using concrete word to describe the abstract concept.During the new century,TCM needs modernization.Clear concept and standard terms are important for modernization of TCM.Meanwhile,there was confusion on translation of terms on the internationalization of TCM.Standard terms were precondition of the academic exchange and popularizing TCM.In a word,the standardization of terms of TCM became one of the keys for the modernization and internationalization of TCM.

The development of formulas in the Ming Dynasty surpassed the previous dynasties in range and depth.The main achievements of formulas were not only the coming out of Puji Fang and Yifang Kao,but also the diversity of formulas nomenclature and variation,initial perfection of formulas classification and composition,continuous invention of new distinctive formulas,steady increment of remedy books and wide application of preparations.

As a principal part of foreign exchange activities of traditional Chinese medicine, government organizations played a crucial role. At present, there are relatively rare researches on foreign exchange activities of traditional Chinese medicine in government organizations. In this article, we defined related government organizations and their functions, analyzed the features of the foreign exchange activities of traditional Chinese mdicine among government organizations in the past nearly 30 years. And based on this analysis, SWOT theory model in management science was introduced to discuss the reasons of government behaviors and put forward suggestions for the future development.

Hospital information system is indispensable for hospital management,and its evaluation indexes system serves as the cornerstone for evaluation of hospital informationization.Basic evaluation indexes for hospital informationization were earmarked objectively as well as quantitatively and qualitatively,based on expert opinions.The evaluation indexes of hospital informationization consists of six dimensions and 23 secondary indexes.The paper described in detail the data makeup for reference of building the evaluation indexes system of hospital informationization.

Objective To evaluate the efficacy and safety of holmium laser lithotripsy in the management of cholelithiasis. Methods 17 patients with hepatolithiasis or residual stones after bile duct operation were treated by holmium lithotripsy under fibrocholedochoscope. Results 36 stones were confirmed in 17 patients by intraoperative cholangiography. 7 stones were removed directly, 24 ones by laser lithotripsy, with success rate being 82 8%(24/29). Due to located in superior segmental intrahepatic duct, other 5 stones could not be observed under fibrocholedochoscope, so they weren't treated by holmium laser lithotripsy. B ultrasoundgraphy and cholangiography showed no residual stones in extrahepatic bile duct at the 1st month postoperatively, and the untreated 5 stones were in the same place. No hemorrhage, bile leakage, liver dysfunction or other complications occurred. Conclusions Holmium laser lithotripsy under fibrocholedochoscope is an effective and safe method in the management of hepatolithiasis or residual stones after bile duct operation.

Objective:To establish an HPLC method to determine the content and related substances of cefetamet pivoxil hydro-chloride tablets. Methods:A Hypersil ODS2 C18 (250 mm × 4. 6 mm,5 μm) column was used. The mobile phase was 0. 005 mol· L-1 tetrabutylammonium hydroxide solution-acetonitrile (64: 36, adjusting pH to 4. 5 with phosphoric acid). The flow rate was 1. 0 ml·min-1 . The detection wavelength was 232 nm. The column temperature was 30℃ and the injection volume was 10 μl. Results:Cefetamet was completely separated from the related substances. The equation of linear regression was Y=2.29 ×104X-4.30 ×104(r=0. 999 9) and the linear range of cefetamet was 51. 01-510. 07 μg·ml-1 . The average recovery was 99. 60% and RSD was 0. 84%(n=9). Conclusion:The method is simple, accurate and suitable. It can be used for the determination of content and related sub-stances of cefetamet pivoxil hydrochloride tablets.

Objective To construct recombinant baculovirus expression vector containing hepatitis C virus(HCV) truncated core gene and EGFP gene,and to study the antigenicity of the fusion protein expressed in Sf 9 cells.Methods PCR-amplified HCV truncated core gene and EGFP gene were cloned into the transposed vector pFastBac1 to construct a recombinant plasmid pFastCt-EGFP,by which E.coli DH10Bac was transformed to get the recombinant BacmidCt-EGFP.Insect Sf 9 cells were transfected with BacmidCt-EGFP and the expression of fusion protein Ct-EGFP was screened by SDS-PAGE and Western blotting.Results SDS-PAGE and Western blot analysis showed that fusion protein Ct-EGFP was expressed with the molecular mass of 40 kD.ELISA results showed that the fusion protein reacted with 15 of 28(54%) anti-HCV positive sera.Conclusion The fusion protein Ct-EGFP was expressed in insect Sf9 cells and showed partial antigenicity.

Intercellular adhesion molecule -1 is closely related to the occurrence,development and me mastasis of liver cancer.A variety of inflammatory cytokines and stimulus effect on the expression of Intereclluar adhesion molecule-1 through Nuclear factor-kappa B signal transduction pathways.In the stage of inflammation,hepatocirrhusis and tumor,Intercelluar adhesion molecule-1 is expressed differently,and makes different effects on different cells,to promote the occurrence and metastasis of tumor.Diagnostic significance of Intercelluar adhesion molecule1 is to diagnose hepatocellular carcinoma with AFP-negative or suspected-positive more early.What's more it can prognosticate the metastasis and prognosis of liver cancer as a biomarker.Many new treatments of liver cancer are based on the effects on Intercelluar adhesion molecule-1 in different levels producing antitumor function.

The new educational system integrating both medical undergraduate and professional degrees,by integrating the curriculum system rationally,strengthening the clinical practice,innovating the assessment and management mode,establishes and enforces normative resident physician training system to cultivate high-starting point general practitioners led by medical colleges and provide qualified general practitioners,for the purpose of supporting the health reform successfully.