Objective To explore the detection meaning of D-dimer(D-D) and fibrinogen(Fg) in patients with coronary disease.Methods 150 patients with coronary disease were randomly divided into UA group,SA group and AMI group,the D-D was detected by ELASA double resistance to clip method and Fg was detected by CLIUSE methods.Results The D-D in SA group,UA group and AMI group showed significant difference between two groups (SA:UA,t =9.340;SA:AMI,t =18.334; UA:AMI,t =10.240.all P ＜0.01 ).The Fg in SA group,UA group and AMI group showed significant difference between each two groups ( SA:UA,t =11.376; SA:AMI,t =11.730; UA:AMI,t =3.121.all P ＜0.01 ).D-D between one coronary artery disease and two coronaries artery disease,three coronary arteries disease showed significant difference( t =7.017,15.603,all P ＜ 0.01 ) ; and between two coronaries artery disease and three coronary arteries disease showed significant difference,too ( t =8.662,P ＜ 0.01 ).The Fg between one coronary artery disease and two coronaries artery disease,three coronary arteries disease,showed significant difference( t =8.687,11.855,all P ＜ 0.01 ) ; and between two coronaries artery disease and three coronary arteries disease showed significant difference,too( t =4.379,P ＜ 0.0 1 ).Conclusion The D-D and Fg showed obvious difference between different types of coronary disease,and the levels increase along with the disease degrees of coronaries

The present study attempts to investigate the influence of the immune response upon the immunoreactive ?-endorphine (ir-?-EP) levels in anterior lobe (AL) and neurointermediate lobe (NIL) of pituitary and hypothalamus after immunizaion of male adult Wistar rats with sheep erythrocytes by a single intraperitoneal injection. The results showed that the decrease of ir-?-EP concentration in AL tended to be concomitant with the direct plaqueforming cells (direct PFC) level increased. In the 3rd day after immunization, when a few PFC began to appear, the concentration of ir-?-EP in AL decreased significantly (P

OBJECTIVE:To survey the current situation and the trend of the use of the herb injection.METHODS:In?formation concerning the consumption amount and manufacturer of herb injection used in21hospitals of Hangzhou in2002～2003was investigated.The use of herb injection was statistically analyzed by means of sequencing the consumption amount.RESULTS:The consumption amount of the herb injection increased annually;Kanglaite,Shenmai injection ranked in the first place in consumption amount,then those for skeleton disease,cardiovascular and cerebrovascular diseases and hepatic diseases such as Xingnaojing,Gegensu,Ciwujia,Danshen injection.CONCLUSION:There is a great potential for the development of herb injection and the consumption both in money and quantity of herb injection will increase rapidly.

In order to evaluate the effect of Token Test for comprehension ability of Chinese aphasia,33 aphasics with different types due to left hemispheric damages were conducted in this study of Token Test and Aphasia Battery in Chinese(ABC).The statistic analysis showed that the score of Token Test was significant correlated with the comprehension ability,word recognition and dictation of Chinese language,construction and visual-spatial function,praxia,calculation,attention and memory ability(P<0.01)and significant correlated with the severity of their aphasia(P<0.05).This study revealed that the score of Token Test was influenced by the type and the severity of Chinese aphasia especially the comprehension ability of speech and also influenced by attention,memory,praxia,visual-spatial function,cognition,etc.Token Test was a very sensitive test of measuring the comprehension ability for Chinese speech.

Objective:To evaluate the clinical efficacy of Shiwei-Jinghuang Ointment combined with Chinese herbal external washing prescription in the treatment of acute paronychia. Methods:A total of 126 patients with acute paronychia in Xiyuan Hospital of China Academy of Chinese Medical Sciences from January to December 2019, who met the inclusion criteria, were divided into 3 groups according to the random number table method (42 in each group). The treatment group was treated with Shiwei-Jinghuang Ointment combined with Chinese herbal external washing prescription. The control group 1 and group 2 were simply applied with Chinese herbal external washing prescription and mupirocin ointment, respectively. All groups were treated for 2 weeks and followed up 2 months. Serum CRP level was determined by ELISA method, and neutrophil percentage (NEU%) was measured by automatic hematology analyzer. The subsided time of red swelling and inflammatory exudation in nail groove of the paronychia patients were observed and recorded. Results:The total effective rate was 90.5% (38/42) in the treatment group, 71.4% (30/42) in the control group 1 and 66.7% (28/42) in the control group 2. The statistical difference were significant among three groups ( χ2=7.350, P=0.025). After treatment, the serum CRP level and NEU% in three groups were decreased ( P<0.01), and the serum CRP and NEU% level in treatment group were significantly lower than those in the control group 1 and group 2 ( F values were 6.482, 33.619, respectively, all Ps<0.001). After 2 months of follow-up, the incidences of chronic paronychia were 50.0% (6/12) and 57.1% (8/14) in control group 1 and group 2, respectively, but no chronic paronychia occurred in the treatment group. The difference among three groups was statistically significant ( χ2=9.355, P=0.009). Conclusion:The combination of Shiwei-Jinghuang Ointment and Chinese herbal external washing prescription can promote paronychia red swelling, reduce the inflammatory exudation time and the incidence of chronic paronychia, effectively improve the in vivo decrease inflammation index and clinical efficacy.

The diatom test has been used as a main diagnotic method of drowning.but itis doubful and even is considered valueless by some authors nowadays for it hasbeen proved by Niles Forged(1983)that the diatoms found in the internal organsof submerged corpses might be inspired into the body during fhe lifeWe believed that the diagnosis of drowning might be made by examining lungchlorophyll(a)of planktons with spectro-fluorophotometer qualitatively and quantitatively.According to our experimental stuudiesIt is confirmed that this method could be used for the diagnosis of drowning.Mean while two cases submerged in water were investigate.and the causesof deathwere diagnosed correctly.It is concluded that the examination of the lungchlorophyll(a)of planktoms could be used as a reliable diagnostic method infore nsic practice

Objective To study the clinical features and pathogenesis of non-traumatic rhabdomyolysis (RM). Methods The causes andclinical features of 11 patients with non-traumatic RM were analyzed retrospectively. Results The causes of non-traumatic RM includeddrugs (3 cases), carbon monoxide poisoning (2 cases), intensive exercise training (2 cases), strenuous farming work (1 cases) and others (3cases). The clinical presentations included muscular weakness, myalgia, muscle swelling, pigmented urine and acute renal failure. The activityof serum creatine kinase increased, electrolyte derangements were common complications. Conclusion Prescribed drugs are the mostcommon cause of non-traumatic RM. The diagnosis of non-traumatic RM is chiefly based on clinical presentations and high levels of serumcreatine kinase. Acute renal failure is the most severe complication and cause of death.

Objective To study the characteristics of hypothyroid myopathy in adults. Methods The clinical, biochemical, electromyographic, and pathologic characteristics of 19 patients with hypothyroid myopathy were analysed retrospectively. Results Proximal muscle weakness and elevation of muscle enzymes were the most common features. Other common clinical manifestations were myalgia, cramps, pseudomyotonia or stiffness after exercise. Muscular weakness with pseudohypertrophy was presented in some patients. Myoedema of temporal muscle was elicited by chewing continually. Hypothyroidism may be related to the pathogenesis of myasthenia gravis. Patients treated with levothyroxine achieved satisfactory outcomes. Hypothyroid myopathy is different from polymyositis in many aspects. Conclusion All patients presenting muscular weakness or elevation of muscle enzymes should be studied with their function of thyroid in order to avoid misdiagnosis.

Objective To investigate the mean values of carotid intima-media thickness (IMT) and change features according to gender,segments and age groups in general Chinese population,and provide the basis for the health assessment of carotid ultrasound.Methods GE LOGIQ 7 ultrasound scanner was used to measure IMT of 743 healthy cases aged from 38 to 70 years old.Six segments(bilateral common carotid artery,bilateral carotid bulb,bilateral internal carotid artery) were measured for each case.All patients were divided into 6 age groups across 5 years to be one group.The mean values for each group was calculated.Results The average age of the three sections of carotid IMT gradually increasing linearly related; minimal change in men and women,the magnitude of the age of the internal carotid artery IMT;sinus IMT were greater than the common carotid artery IMT and carotid artery IMT thinnest.the mean carotid IMT of Men and women in the same age group,compared to the 46-50 group,the group of 51-55,56-60 group,the differences were significant (P ＜ 0.05);men and women 41-45 group and 61-65 difference between the groups was not statistically significant (P ＞ 0.05);mean IMT difference of the male groups compared with the older group of women was not statistically significant (P ＞ 0.05).Conclusion Ultrasound scanner can be used to measure IMT accurately.In the 46-60 group,carotid IMT thickening in men than women about 5 years earlier.The mean IMTs for different sex,age groups and segments would greatly benefit vascular health evaluation.It has a great significance in the prevention of cardiovascular and cerebrovascular diseases.

This paper reviewed and analyzed the whole 29 years' compiling and revising histo-ry of Neurology the 5-year programming textbook for national undergraduates. The textbook has been becoming a high-quality textbook with novelty, practicability, readability and systematicness, conform-ing to the need of national education reform and reflecting the characteristics of neurology. Through the review of textbook history, we know that material construction can deepen the educational reform, improve the teaching level and discipline development, promote quality education and personnel train-ing.