[Objective] To summarize the clinical experience on treating thoracic spinal little joints disorder by manipulation of embracing cervical and extracting chest. [Method] To col ect and analyze the theory and methodology of Pro.Fan's clinical treatment on thoracic spinal little joints disorder. [Result]Professor Fan has rich clinical experience for many years in the study and treatment of spinal diseases. He puts forward theories of“close relationship between symptoms with etiology”and“correct spinal little joints disorder”, that is to say, considering symptoms to detect it's etiology, thinking etiology to find out it's dislocation, the method of treatment is removing pathogeny, etiology is removed, symptoms are removed. Based on the theory, Pro.Fan invents the manipulation of “embracing cervical and extracting chest”to treat thoracic spinal little joints disorder.And this manipulation has significant effect on clinic. [Conclusion] Pro.Fan has great innovation on treatment of thoracic spinal little joints disorder and the manipulation of“embracing cervical and extracting chest”has significant effect on clinic.

Forty five patients with acute cerebral infarction were randomized to two groups: in treatment group patients received local subhypothermia and conventional therapy, in control group patients received conventional therapy only. Clinical outcome was assessed by the National Institutes of Health Stroke Scale (NIHSS) on admission and at 7, 14 and 30 d after treatment. Serum neuron specific enolase (NSE), nitrogen monoxide ( NO ) , superoxide dismutase (SOD), interleukin-6 (IL-6 ) and intercellular adhesion molecule-1 (ICAM-1) were detected on admission and at 7,14 d after treatment The study showed that NIHSS scores of treatment group on 14, 30 d were lower than those of control group ( P ＜ 0. 05 ). Serum NSE, NO, IL-6 and ICAM-1 levels significantly decrease; while serum SOD levels increased (P ＜ 0. 05). In conclusion, local subhypothermia therapy can inhibit inflammatory reaction, reduce oxygen free radical formation and improve neurological function in patients with acute cerebral infarction.