Anaplastic large cell lymphoma (ALCL) represe nt s a distinct category of large cell lymphomas defined by a strong expression of the cytokine receptor CD30 on neoplastic cells and a so-called anaplastic cytol ogy. This review will address the recent progress in understanding ALCL.

OBJECTIVE:To investigate the effects of application timing of carboporst tromethamine on postpartum hemor-rhage and hemodynamics of cesarean section women with centralplacenta previa. METHODS:Totally 138 parturient women with central placenta previa selected from our hospital during Jan.-Dec. 2015 were divided into observation group and control group ac-cording to random number table,with 69 cases in each group. Both groups received cesarean section. Control group was given Car-boporst tromethamine injection 250 μg on uterine body after the delivery of placenta. Observation group was given Carboporst tro-methamine injection 250 μg on corpora uteri immediately after umbilical cord cutting. The operation duration,intraoperative and postoperative blood loss were observed in 2 groups. The preoperative and postoperative 24 h hemodynamic index,coagulation func-tion and corpora uteri were compared between 2 groups. RESULTS:The operation duration of observation group was significantly shorter than control group;intraoperative blood loss and 24h blood loss of observation group were significantly less than control group,with statistical significance(P<0.05). There was no statistical significance in preoperative hemodynamic index and coagula-tion function index between 2 groups before surgery(P>0.05). 24 h after surgery,SBP,DBP,MAP,FIB and D-D of 2 groups were decreased significantly,while HR of them were increased significantly;the observation group was significantly better than the control group,with statistical significance (P<0.05). There was no statistical significance in the incidence of ADR (15.94% vs. 13.04%) between 2 groups (P>0.05). CONCLUSIONS:Carboporst tromethamine after omphalotomy via uterine body helps to shorten the operation time,reduce intraoperative blood loss,maintain hemodynamic indexes stable and improve coagulation func-tion of cesarean section women with central placenta previa ,with good safety.

Treatment of an aneurysm with a mesh stent alone becomes an emerging technique. The mechanism involves the mesh stents, when it crosses the neck of an aneurysm could change the internal circulation and induce the formation of stable thrombus and in turn assists the growth of neointima for anatomical healing of the aneurysmal neck. The mesh stent technique aimed at vascular reconstruction with expected curing effect for aneurysm together as a simple and safe way to keep the patency of the small arterial branches, just contrary to the covered stent. This technique couldn't be carried out practically in wide scale because of immaturity, therefore we give a comprehesive review in the progress of this field.

70%(59 male and 22 female,mean age 61?11 years)were enrolled in the study,IVUS was done in 55 cases before and after percutaneous coronary intervention(PCI)with 24 patients from the SFCT group and 31 patients from the conventional percutaneous coronary angioplasty(POBA).Quantitative coronary angiography(QCA)measurements included minimal lumen diameter(MLD),reference lumen diameter(RLD)and diameter stenosis(DS);IVUS measurements include external elastic membrane area(EEMA),minimal lumen area(MLA),and area stenosis(AS),style of endomembrane tear and dissection.Results All the target lesions were successfully dilated in both groups without serious complications.Mean dilated pressure was lower in the SFCT group than that in the POBA group(871.4 kPa vs 1 013.2 kPa P

Objective To evaluate the susceptibility to toenail fungal infection (FI) in the elderly. Methods Two hundred patients with toenail FI aged 60 years or older from 2005 to 2007 in our hospital were collected in our study, including one hundred elderly patients with toenail fungal infection (case group) and one hundred elderly patients without toenail fungal infection (control group). The clinical data of the patients in two groups were analysed. Results In case group, diabetes mellitus was the most common complication, accounting for 24% (24/100), while there were only 6 cases with diabetes mellitus (6%) in control group (P<0. 05). In case versus control group, there were 31 cases vs 12 cases with lower extremity varicose vein (P<0. 05), and 36 cases vs 19 cases with foot deformity, 11 cases vs 3 cases with toenail onychomychosis following trauma of their toes (P<0.05) ,32 cases vs 12 cases with history of wearing tight shoes (P<0. 05). In case group, 12 of 47 female patients used to wear high-heel shoes. Conclusions Toenail trauma, foot malformation, lower extremity varicose vein and diabetes mellitus are predisposing factors for toenail onychomycosis in the elderly.

Objective To evaluate the safety and efficacy of resection (EMR) of gastrointestinal tumors by EUS assisted with high-frequency probe EUS (HFPE). Methods EMR assisted with HFPE was attempted in 30 patients with gastrointestinal tumors with 0. 5 - 3. 5 cm in diameter. Complications such as bleeding and perforation were carefully monitored. The entire resected specimen received histopathological examination. Follow-up was regularly taken in outpatient clinic. Results In 28 (93. 3% )out of 30 patients tumors were successfully resected by EMR. 95. 2% cancerous and 85. 7% tumorous lesions were resected satisfactorily. No severe bleeding or perforation occurred nor had any recurrences be observed when follow-up of 2 ~ 13 months. Conclusion EMR assisted with HFPE is a safe and desired measure in the treatment of early small gastrointestinal tumors.

Objective To explore the diagnostic value of magnifying endoscopy in the identification of chronic atrophic gastritis (CAG) , intestinal metaplasia (IM) and Helicobacter pylori ( Hp) infection. Methods Microstructures of gastric mucosa in 140 cases with different gastric diseases were studied using Olympus GIF-Q240Z magnifying endoscope. Biopsies were taken from the magnified sites. The microstruc-tures of gastric mucosa were compared with the results of pathological study. Results The morphology of gastric pits was classified as follows: Types A ( round spot) , B ( short rod) , C ( branched) , D ( patchy) and E ( villous) . The detection rate of CAG by magnifying endoscopy was 94. 3% (33/35) , which was significantly higher than that by routine endoscopy (22. 8% , 8/35) (P

Objective To explore the expression changes in SHIP1 gene in patients with chronic granulocytic leukemia (CGL), healthy volunteers and the K562 cells (one of human CGL cell lines), and to explore the effects of BCR/ABL expression in K562 cells on the SHIP1 gene by blocking the BCR/ABL expression in K562 cells with a specific siRNA. Methods The expression levels of SHIP1 mRNA in leukocytes of the patients with CGL, healthy controls and K562 cells were assessed with RQ-PCR. In addition, K562 cells were divided into three groups: control group (untreated), non-specific interference group (treated with non-specific siRNA), and specific interference group (treated with specific siRNA to block BCR/ABL gene). RQ-PCR and Western blotting were employed to examine the expression level of mRNA and protein (P210 and P145) of BCR/ABL and SHIP1 genes. Results The mRNA expression of SHIP1 in CGL patients and K562 cells was significantly lower than that of the healthy controls. The expression of BCR/ABL gene was down-regulated, while SHIP1 gene up-regulated, in the specific interference group. No statistical significant difference was found between the non-specific interference group and the control group. Conclusions The mRNA expression of SHIP1 is lower in patients with CGL than in the healthy control. The specific siRNA can block the expression of BCR-ABL and further suppress the expression of SHIP1.

50 as group B.All patients were examined by CAG.Plaque morphology was assessed by IVUS in 14 of group A and 38 of group B before intervention.Plaque external elastic membrane,minimal lumen area,plaque area,plaque burden,lipid pool area,thickness of fibrous cap and rupture were measured by IVUS.Results Heavy smoking,excess drinking and positive family history were more frequent in group A than those in group B,while hypertension and diabetes mellitus were more common in group B.The percentage multi-vessel lesions and collateral circulation were higher in group B.IVUS results showed that vulnerable and ruptured lesions were found in most of two groups.The severity of plaque burden is milder in group A.However,they had a bigger lipid core and a thinner fibrous cap.Group B showed a more severe stenosis and bigger plaque area.Conclusion Plaque vulnerability and rupture are the most common cause substrate of AMI.There are different risk factors and different coronary artery characteristics in AMI with different ages,which suggests that different emphases should be taken in preventing AMI in patients with different ages.