1.Laryngeal polypus at the ventricular band symptomized firstly by hemoptysis: a case report.
Jianmei YIN ; Lei ZHU ; Weilun CHEN
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(21):1914-1915
Published reports about polyps of larynx at the ventricular bands are extremely rare. The first symptom of this case presents recurrent hemoptysis. The video laryngoscope demonstrated that a smooth-faced and hyperemic polypoid lesion was found in the anterior part of the right false vocal cord, close to laryngeal surface of epiglottis. Postoperative pathological report revealed that the mass was a vascular polyp.
Hemoptysis
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diagnosis
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pathology
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Humans
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Larynx
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pathology
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Polyps
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diagnosis
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pathology
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Postoperative Period
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Vocal Cords
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pathology
2.The detection of coagulation in diabetic mellitus in Xinjang Uygur and Han
Jianmei ZHAO ; Haiyan RONG ; Yousen ZHU
International Journal of Laboratory Medicine 2017;38(2):187-188
Objective To explore the changes of coagulation factors in Xinjiang Uygur and Han patients with diabetic mellitus in order to provide reference for the prevention and treatment of diabetic mellitus patients.Methods 2 100 patients with diabetic mel-litus were taken as the patient group which were diagnosed in our hospital between February 2014 and April 2015,another 446 healthy people were collected as the control group.The difference of coagulation between diabetic mellitus group and control group was compared.Coagulation between Uygur and Han was compared for 2 100 diabetic mellitus patients.Results The APTT of dia-betic mellitus group were significantly less than that in control group(P <0.05).FIB of diabetic mellitus group were significantly higher than that in control group(P <0.05).The difference of PT between diabetic mellitus group and control group were not sig-nificant(P >0.05).The APTT of Uygur group were significantly less than Han group(P <0.05).FIB of Uygur group were signifi-cantly higher than Han group(P <0.05).PT between Uygur group and Han group was not significant(P >0.05).Conclusion Fac-tors were difference of diabetic mellitus patients and healthy people,coagulation factors in diabetic mellitus patients of Xinjang Uygur and Han.
3.Quality Standard Study on Danqi Tablets
Binbin FENG ; Jianmei ZHANG ; Huifeng ZHU
Journal of Zhejiang Chinese Medical University 2007;0(01):-
[Objective] To set up standard method of quality to Danqi Tablets.[Method] Take HPLC to make nature authentication,take reverse HPLC to test the content of salvianolc acid B in the preparation.[Result] The authentication is strong in attribute and has good repetition,the measurement has good linear relation,the recycle rate is 101.7%,RSD 1.77%.[Conclusion] The quality standard can effectively control the quality of Danqi Tablets.
4.Effects of insomnia on heart rate variability in the elderly with hypertension
Jianmei ZHOU ; Enyan YU ; Aihua REN ; Liyue ZHU ; Wanzhen WU
Chinese Journal of Geriatrics 2012;31(1):51-53
ObjectiveTo explore the effects of insomnia on heart rate variety(HRV) in aged hypertension patients. Methods259 subjects were divided into healthy group (74 cases),simple hypertension group (71 cases),coexisting hypertension and insomnia group (114 cases) which was sub-grouped to <5 years,5-9 years and ≥-10 years according to the duration of insomnia.All subjects had 24 h recordings of ECG.The data of HRV time domain (SDNN,SDANN and ASDNN) were collected and compared.ResultsHRV time domain was lower in healthy group than in the other two groups (F=12.02,10.54 and 4.27,P<0.01),and decreased more significantly in coexisting hypertension and insomnia group compared with simple hypertension group(P<0.01).The values of SDNN and SDANN in 5-9 years and ≥ 10 years subgroups decreased as compared with < 5 years subgroup (F=8.63 and 4.54,P<0.01),and these values further lower in ≥10 years subgroup than in 5-9 years subgroup (P< 0.01 ). ConclusionsInsomnia may lead to more serious disorder of automatic nervous system and further aggravated disorders appear in the elderly with hypertension along with increasing years of insomnia.
5.Value of model for end-stage liver disease combined with serum sodium in predicting the prognosis of cirrhosis
Wenting MA ; Jianmei ZHAO ; Hongru ZHU ; Rongli HE
Chinese Journal of Postgraduates of Medicine 2010;33(28):8-11
Objective To evaluate the capability of model for end-stage liver disease (MELD)combined with serum sodium (MELD- Na,MELDNa and MESO scores) in predicting the prognosis of patients with decompensated liver cirrhosis in 6 and 12 months.Methods One hundred and nineteen patients with decompensated liver cirrhosis and completed follow-up data were retrospectively studied.The MELD,MELD- Na,MELDNa and MESO scores were calculated according to the clinical data of each patient.Receiver operating characteristic (ROC) curve and the area under the curve (AUC) was used to measure the values of the four models in predicting the 6 and 12 months survival,and Z-test was used to compare their predictive values.Results MELD,MELD-Na,MELDNa and MESO scores were significantly different between patients who survived and those who died within 6 and 12 months follow-up.The AUC for the MELD- Na,MELDNa and MESO scores were all more than 0.8 in predicting 6 and 12 months survival.However the differences of the AUC between the MELD score and MELD-Na,MELDNa,MESO scores were not significant in predicting 6 and 12 months survival.Conclusion The model for MELD combined with serum sodium can accurately predict the prognosis of patients with decompensated liver cirrhosis in 6 and 12 months,while these scores are not superior to MELD score.
6.Killing effect of 125I-UdR on human lymphoma Raji and Daudi cell Hoes
Jianmei WAN ; Wo FAN ; Youjiu ZHANG ; Ran ZHU ; Zeyang YU
Chinese Journal of Radiological Medicine and Protection 2009;29(1):50-53
Objective To evaluate the killing effect and the uptake of 125I-UdR on human lymphoma Raji and Daudi cell lines. Methods The amount of 125I-UdR in the cells and cell nuclei were determined after incubation of different time in RPMI 1640 culturing medium containing different concentrations of 125I-UdR. The killing effects of 125I-UdR on Raji and Daudi cell lines were estimated through MTT assay and cell cycle was analyzed by propidium iodide (PI) staining. Results The amounts of 125I-UdR in Raji and Dandi cells and cell nuclei were much higher than that of Na125I(P < 0.05). The amounts of 125l-UdR in Raji and Daudi cells were 14414±95 and (6916± 53.69) Bq/106 cell when the concentration was 100 kBq/ml. The amounts of Na125I were 68± 3.8 and (324±32.8) Bq/106 cell. The uptake of 125I-UdR in Raji and Daudi cells and cell nuclei increased with the 125I-UdR concentration and incubated time. The cell surviving fractions of 125I-UdR groups was much lower than that of Na125I groups (P < 0.05). When the concentration was 500 kBq/ml and incubated time was 48 hours, the Raji and Dandi cell surviving fractions of125I-UdR groups were (19.78 ± 1.39)% and (43.17 ± 2.69) % ;those of Na125I groups were (79.10 ± 1.79) % and (80.36 ± 6.12) %. The surviving fractions of 125I-UdR groups reduced with the 125I-UdR concentration. Conclusions 125I-UdR can be specially ingested by Raji and Daudi cells and incorporated into DNA, then the cells will be killed. The uptake of 125I-UdR is dose and time dependent.
7.Association between activity of hand, foot and mouth disease and meteorological factors in Suzhou
Zhengrong CHEN ; Wei JI ; Yuqing WANG ; Yongdong YAN ; Weifang ZHOU ; Xiaoxing KONG ; Jianmei TIAN ; Yan ZHU
Chinese Journal of Infectious Diseases 2012;30(10):609-612
Objective To study the association between activity of hand,foot and mouth disease (HFMD) and the meteorological factors in Suzhou.Methods A total of 17 653 children diagnosed with HFMD in Children's Hospital Affiliated to Suzhou University during 2008 to 2011 were enrolled.The meteorological factors in(c)luding mean temperature,relative humidity,rainfall amount,sum of sunshine and mean wind velocity during Jan 2008 to Dec 2011 were collected monthly.Numeration data were analyzed using chi square or Fisher exact test.Normal distribution data were analyzed using Pearson correlation and non-normal distribution data were analyzed using Spearman rank correlation.Results HFMD could be found all over the year and had obvious seasonality which peaked in Summer,followed by Spring and Autumn and HFMD decreased markedly in Winter.The activity of HFMD was positive correlated with mean temperature(r=0.716,P<0.01),wind velocity (r=0.630,P<0.01),rainfall(r=0.477,P<0.01) and sum of sunshine(r=0.311,P<0.05).No statistical significance was observed between relative humidity and HFMD(r =0.276,P>0.05).Multivariate stepwise regression analysis showed that only mean temperature and rainfall were associated with HFMD and mean temperature had stronger influence on HFMD than rainfall (t =4.687,P < 0.01 ; t =2.258,P < 0.05).Conclusions HFMD has obvious seasonality.Mean temperature and rainfall are the main factors affecting this seasonality.
8.Effects of pioglitazone on the expression of adipose triglyceride lipase in obese rats
Chuaoyu ZHU ; Xiaohua LIU ; Jianmei ZHANG ; Miao XU ; Li WEI ; Weiping JIA
Chinese Journal of Endocrinology and Metabolism 2012;28(6):509-511
To detect the effects of pioglitazone on adipose triglyceride lipase (ATGL) in adipose,liver,and muscle of high-fat diet-induced obese rats.Insulin resistance aud decreased expression of adipose triglyceride lipase were found in the adipose,liver,and muscle tissues.Pioglitazone may improve insulin sensitivity and ameliorate ATGL expression in tissues of high-fat diet-induced obese rats.
9.Research on the relationship between proinflammatory cytokines and cognitive function in patients with mild cognitive impairment
Enyan YU ; Wanzhen WU ; Aihua REN ; Liyue ZHU ; Jianmei ZHOU ; Qiang WANG
Chinese Journal of Geriatrics 2013;32(7):714-716
Objective To investigate the relationship between proinflammatory cytokines and cognitive function in patients with mild cognitive impairment (MCI).Methods From May 2007 to May 2009,70 patients (aged ≥ 60 years) with MCI were collected.Among them,50 cases were amnestic MCI,and 19 cases developed into AD.The cognitive function was assessed,and all patients were followed up.The venous blood samples were obtained and proinflammatory cytokines (IL-1α,IL 1β,IL-6,TNF-α) were detected by using enzyme linked immunosorbent assay.Results There were differences in the levels of proinflammatory cytokines between patients with aMCI and patients with Alzheimer's disease (AD) [IL-1β,(40.5 ± 7.7) μg/L vs.(38.6 ± 7.3) μg/L ; IL 6,(70.4 ±24.3) μg/'L vs.(53.6±20.5) μg/L;TNF-α,(58.6±13.5) μg/'L vs.(50.3±-17.1) μg/'L;t=3.537,2.229,2.226,P=0.002,0.039,0.039,respectively].Conclusions MCI is a preclinical state of AD.The cognitive function damage of MCI patients are different from that of AD patients,and the immune status of MCI patients is also changed.
10.Comparison of 3H-TdR and 125Ⅰ-UdR incorporation on the proliferation effect of lymphocytes
Jianmei WAN ; Youjiu ZHANG ; Wo FAN ; Ran ZHU ; Ping NING ; Fengmei CUI
Chinese Journal of Radiological Medicine and Protection 2010;30(6):658-660
Objective To compare the incorporation method of 3H-TdR and 125Ⅰ-UdR on determining the proliferation effect of lymphocytes. Methods The proliferation effects of lymphocyte and Daudi lymphoma cells were estimated by 3H-TdR and 125Ⅰ-UdR incorporation. Results The incorporating fraction of 3H-TdR and 125Ⅰ-UdR into lymphocyte was 20.95% ± 1.06% and 1.00% ±0.04%,respectively, and the incorporating fraction for the lymphoma cells was 29. 94% ± 4. 10% and 6. 02% ±0. 73% ,respectively. The incorporation fractions of 3H-TdR into lymphocyte and lymphoma cells were much higher than those of 125Ⅰ-UdR, but the incorporating fractions of 3H-TdR or 125Ⅰ-UdR into the lymphoma cells were much higher than those of lymphocytes. Conclusions For lymphocytes, 125Ⅰ-UdR cannot substitute 3H-TdR as a tracer agent. But for lymphoma cells, whether 125Ⅰ-UdR could be replace 3H-TdR or not needs further research.