1.THE DISTRIBUTION OF HFE GENE MUTATION IN CHINESE ADULT MEN
Jianhong LI ; Jianhua PIAO ; Xiaoguang YANG
Acta Nutrimenta Sinica 1956;0(04):-
Objective:To analyze the distribution of HFE gene (hemochromatosis gene) mutation in normal and iron overload men and discuss the influence of HFE gene mutation on iron overload status of Chinese adult men..Method:The data of 226 normal and 331 iron overload men were drawn from National Nutrition and Health Survey in 2002 as control and case group respectively to analyze and compare the distribution of HFE mutation including C282Y mutation, H63D mutation and S65C mutation in normal and iron overload men.Results:In case group, normal gene was 90.03%, homozygosity for H63D mutation 0.6%, heterozygosity for H63D mutation 9.07%, heterozygosity for S65C 0.3%. In control group normal gene was 94.25%, heterozygosity for H63D 5.75%, and no S65C and C282Y mutation was detected. Conclusion: HFE gene mutation was not the major reason resulting in iron overload in Chinese adult men.
2.STUDIES ON THE CRITICAL VALUE OF sTfR FOR ASSESSING IRON OVERLOAD IN CHINESE ADULT MEN
Jianhong LI ; Jianhua PIAO ; Xiaoguang YANG
Acta Nutrimenta Sinica 2004;0(05):-
Objective:To study the critical value of soluble transferring receptor (sTfR) for assessing iron overload in Chinese adult men. Method:226 normal iron status and 331 iron overload men were drawn from National Nutrition and Health Survey 2002 as control group and case group respectively. To compare the sTfR concentration and distribution between two groups and ascertain the sTfR critical value to assess iron overload by ROC curve. Results:The concentrations of sTfR were 1 325.46?484.92 ng/ml, 1 788.56? 457.02 ng/ml in case group and control group respectively, the former lower than the latter (P
4.DIFFERENT FEEDING PRACTICES OF CHINESE INFANTS WITHIN FOUR MONTHS OF AGE IN 2002
Shian YIN ; Jianqiang LAI ; Jianhua PIAO ; Xiaoguang YANG
Acta Nutrimenta Sinica 1956;0(03):-
Objective:To study the different feeding practices of Chinese infants within four months of age in 2002. Method:The method of multi-steps cluster sampling was adopted. In order to ensure the sample size sufficient additional subjects were included in this survey. Results:More than two thirds (71.6%) of infants within four months of age had been almost exclusively breastfed, 65.5% and 74.4% in urban and rural areas respectively. The average percentage of mixed feeding was 23.0% (27.0% in urban and 21.2% in rural areas); and that of artificial feeding was 5.4% (7.5% in urban and 4.4% in rural areas). The rate of breastfeeding decreased with the increase of family income. Conclusion:Although the rate of almost exclusive breastfeeding is increasing, there is still far away from the aim of 85% in 2001-2010 National Outline for Children.
5.EFFECTS OF THE GENETICALLY MODIFIED RICE ENRICHED WITH RESISTANT STARCH ON LARGE BOWEL HEALTH IN RATS
Min LI ; Jianhua PIAO ; Qiaoquan LIU ; Xiaoguang YANG
Acta Nutrimenta Sinica 2004;0(06):-
Objective To study the effects of the genetically modified(GM) rice enriched with resistant starch on large bowel health in rats. Method Forty-eight healthy male SD rats were randomly assigned into four groups based on body weight,and given with no-GM rice diet (No-GM), GM rice diet(GM), half-GM rice diet (Half-GM) and normal diet (ND), respectively. After fed for 5 w, 4 d feces samples were collected. At 6 w all rats were killed and the contents of cecum and colon were collected. Large bowel function was evaluated by determination of cecum and colon weight, their contents, pH value, short-chain fatty acids (SCFA), etc. Results GM group had similar body weight with ND and significantly less than No-GM. Compared with No-GM and ND, fecal bulk and moisture, cecum and colon weight and the cecum contents of GM and Half-GM were higher dose-dependently. The contents of SCFA in cecum, colon and feces dropped gradually. SCFA level of cecum and colon was higher significantly in GM and Half-GM compared with No-GM and ND except butyric acid of colon in Half-GM. In all groups, there were differences of acetic and propionic acid level in feces but no difference of butyric acid. Cecum and fecal pH value of GM and Half-GM dropped much significantly compared with No-GM and ND. Conclusion The genetically modified rice enriched with resistant starch can improve the large bowel health of rat.
6.COMPARISON OF METABOLIC BALANCE AND FECAL MORNITORING METHODS FOR ESTIMATING THE DIETARY ZINC ABSORPTION IN TIBETAN MEN
Jichang ZHOU ; Qing JIA ; Junrong HONG ; Jianhua PIAO ; Xiaoguang YANG ; Chengyu HUANG
Acta Nutrimenta Sinica 1956;0(04):-
Objective: To compare the methods of metabolic balance (MB) and fecal monitoring (FM) for evaluating the dietary zinc (Zn) absorption in Tibetan men. Methods: In 14 d field trial on 16 adult Tibetan men, capsules of carmine were given to mark the feces from D4 to D12, and samples of diet, water, feces and urine were collected during the period. In addition, 4.0 mg zinc tracer (enriched with 67Zn) and 1.0 mg recovery indicator ytterbium (Yb) were orally administrated to the subjects in the evening meal of the D5. The ratio of 67Zn/68Zn in fecal samples was determined by inductively coupled plasma mass spectrometry, and then the zinc absorption was calculated based on the principle of isotope dilution. Results: The dietary zinc absorption in Tibetan men was (23.8?3.9) % evaluated by MB and (21.4?4.3) % by FM with significant difference (by paired-samples t test) and linear correlation (Pearson). The unabsorbed zinc tracer and Yb had the similar behavior through the digestive tract, mostly excreted within5 d following the intake. Conclusion: In the 14d metabolic period, the dietary zinc absorption from MB was a little higher than that from FM. Using FM, the metabolic period can be shortened to 4-5 days according to excretion of Yb. Both methods suggested that the dietary zinc absorption in the adult Tibetan men was good.
7.Evaluation of the factorial method for determination of energy expenditure in 16 young adult women living in China.
JianMin LIU ; JianHua PIAO ; Rui SUN ; Ying TIAN ; XiaoGuang YANG
Biomedical and Environmental Sciences 2011;24(4):357-363
OBJECTIVEThe present study aimed to evaluate the accuracy of the factorial method for estimating energy needs in individuals living in China.
METHODSSixteen healthy female adults aged 22.1±1.2 years with a body mass index (kg/m(2)) of 20.4±1.7 were selected as subjects. In free-living conditions, energy expenditure (EE) was determined by using the factorial method. At the same time, the doubly labeled water method (DLW) was also used to measure energy expenditure of the subjects and served as the criterion method. EE predicted by the factorial method (EE(factorial)) was compared with the simultaneous measurement of EE by the validated DLW method (EE(DLW)).
RESULTSThere was excellent agreement between EE(factorial) (7.46±0.59 MJ/d) and EE(DLW) (7.64 ± 0.49 MJ/d), with a difference of -2.6±4.9% (-0.18±0.36 MJ/d). No significant differences were found between the two methods. EE(factorial) was highly correlated with EE(DLW) (r=0.795, P<0.001) and a good agreement for individuals was found by using the Bland and Altman test.
CONCLUSIONThe factorial method gives satisfactory estimates of EE for both groups and individuals living in China.
Adult ; China ; Energy Metabolism ; physiology ; Female ; Humans ; Motor Activity ; physiology ; Radioisotope Dilution Technique ; Young Adult
8. Study on vitamin A nutritional status of 6- to 17-year-old urban children and adolescents between 2010 and 2012 in China
Yu ZHANG ; Xiaobing LIU ; Lichen YANG ; Jing CHEN ; Rui WANG ; Xiaoguang YANG ; Jianhua PIAO ; Deqian MAO
Chinese Journal of Preventive Medicine 2017;51(2):117-120
Objective:
To investigate the vitamin A nutritional status of 6- to 17-year-old urban children and adolescents by analyzing serum retinol level, between 2010 and 2012 in China.
Methods:
Data were obtained from the China Nutrition and Health Survey in 2010-2012. Using multi-stage stratified sampling and the population proportional stratified random sampling method, 6 617 children aged 6-17 years from 32 metropolis and 41 middle-sized and small cities of China were selected. The questionnaire survey was used to collect demographic information. Blood samples were analyzed using high-performance liquid chromatography to determine serum retinol concentration, and the World Health Organization guidelines were used to evaluate the nutritional status of vitamin A. Vitamin A levels, vitamin A deficiency, and marginal vitamin A deficiency in children with different characteristics were compared.
Results:
A total of 3 785 cases with valid samples were obtained. The overall mean serum retinol concentration level was (1.49±0.71) μmol/L; the mean serum retinol concentration was (1.55±0.69) μmol/L for metropolis and (1.49±0.75) μmol/L for middle-sized and small cities (
9.Study on the anemia status of Chinese urban residents in 2010-2012.
Yichun HU ; Jing CHEN ; Min LI ; Weidong LI ; Yanhua YANG ; Lichen YANG ; Rui WANG ; Jianhua PIAO
Chinese Journal of Preventive Medicine 2016;50(3):213-216
OBJECTIVEThe level of blood hemoglobin and the anemia status of Chinese urban residents in 2010-2012 was analyzed.
METHODSAll the data in this study came from the China Nutrition and Health Survey in 2010-2012. By using multi-stage stratified sampling and population proportional stratified random sampling method, 74 276 residents aged above 6 from 34 metropolis and 41 middle-sized and small cities were included in this study. The concentration of blood hemoglobin was determined by cyanmethemoglobin method. Anemia was judged by the anemia standard recommended by WHO, combined with elevation correction standard. The level of blood hemoglobin, the prevalence of anemia and the 95%CI value were analyzed by using the complex sampling weighted processing, combined with the population figures released by the National Bureau of Statistics in 2009.
RESULTSIn 2010-2012, the level of blood hemoglobin of Chinese city population was(144.16 ± 0.78)g/L, (152.88 ± 0.94)g/L for male and(135.01 ± 0.71)g/L for female, while (145.65 ± 1.22)g/L for metropolis and (143.90 ± 0.89)g/L for small and medium-sized. The anemia prevalence of Chinese city population (pregnant women were not included) was 9.7%(95%CI: 9.4%-10.1%), 6.8%(95%CI: 6.4%-7.3%) for male and 12.8%(95%CI: 12.2%-13.4%) for female, while 8.5%(95% CI: 8.0%-9.0%) for metropolis and 10.0%(95%CI: 9.5%-10.4%) for small and medium-sized. The anemia prevalence of 18-44 women (15.4%, 95%CI: 14.3%-16.6%) was the highest among all the age-groups, and the average anemia prevalence of people more than 60 years-old (including) (12.5%, 95%CI: 11.8%-13.2%) was higher than the other age-groups.
CONCLUSIONThe anemia prevalence of Chinese city population in 2010-2012 was obviously decreased in comparison of 10 years ago, while, more attention and improvement measures should be take upon women at reproductive age and the elder people.
Adolescent ; Adult ; Anemia ; epidemiology ; China ; epidemiology ; Cities ; Female ; Health Surveys ; Hemoglobins ; analysis ; Humans ; Male ; Methemoglobin ; analogs & derivatives ; analysis ; Middle Aged ; Nutritional Status ; Prevalence ; Urban Population ; Young Adult