1.Analysis of the effect of pterygium treated by different clinical methods
Chinese Journal of Primary Medicine and Pharmacy 2013;20(14):2097-2099
Objective To compare the clinical efficacy of pterygium treated by grafting auto conjunctiva and amniotic membrane transplantation.Methods 82 patients with primary pterygium were selected,and the number of affected eyes was 97.The eyes were randomly divided into A group and B group.Grafting auto conjunctiva was used in A group after pterygium cut,while amniotic membrane transplantation used in B group.The situation of conjunctiva and cornea and the proliferation of artery and pterygium were observed.Results The mean time of epithelial healing time in A group (5.21 ± 1.08) d was significantly shorter than that (7.16 ± 1.57) d in B group (t =5.973,P <0.05).The relapse rate in A group was 2.04%,which was lower than 16.67% in B group (x2 =29.364,P < 0.05).Conclusion The relapse rate after pterygium cut in surgery could be reduced by grafting auto conjunctiva with cornea,and the speed of corneal wound repair could be accelerated.The effect was good,and it was worthy of clinical application.
2.Recent advances of thymic stromal lymphopoietin in respiratory tract infection
International Journal of Pediatrics 2010;37(6):591-593
Thymic stromal lymphopoietin (TSLP) is an epithelial cell-derived cytokine. TSLP exerts a profound influence on the polarization of dendritic cells and T helper2 cytokine production. TSLP also directly promotes T-cell proliferation in response to T-cell receptor activation and Th2 cytokine production. TSLP affects different populations of cells,indicative of the broad role of TSLP in the regulation of respiratory tract infected and inflammatory processes.
3.HPLC Determination of Berberine Chloride in Lianpu Shuangqing Tablet
Traditional Chinese Drug Research & Clinical Pharmacology 2000;0(05):-
Objective To determine the berberine chloride content in Lianpu Shuangqing Tablet and to develop a steady and reliable method for the quality control of the tablet.Method A HPLC method was adopted.The column was Dionex C18 (5 ?m,4.6 mm ?150 mm)with the column temperature of 28 ℃,the mobile phase was acetonitrile-0.033 mol/L potassium dihydrogen phosphate(25 ∶75) with the flow rate of 1.0 mL/min,and the detection wavelength was at 346 nm.Results Berberine chloride has a linearity in the range of 0.153~1.224 ?g,and the average content in the tablet was 1.26 mg/tablet.Conclusion This method is simple,accurate,and can be used for the quality control of Lianpu Shuangqing Tablet.
4.Effects of long-term administration of amlodipine on the intima-media thickness and the endothelium-dependent vasodilative function of carotid artery in elderly patients with hypertension
Chinese Journal of Geriatrics 2000;0(06):-
Objective To evaluate the clinical effects of amlodipine on structure and function of atherosclerotic artery in elderly hypertensive patients. Methods The intima-media thickness(IMT) and the inner diameter of carotid artery at rest and overpressure of brachial artery as well as after sublingual nitroglycerin administration were measured with amlodipine by color Doppler ultrasonograms before and after long-term (36 months) treatment. The hypertensive patients (76 cases) were divided into 3 groups according to the value of IMT. Group A, n = 21, IMT +1s. Results The blood pressure was controlled to therapeutic aim and maintained stable after 8 weeks treatment with amlodipine. The carotid artery IMT of hypertensive patients was lowered significantly and the endothelium-dependent vasodilative function of common carotid artery was improved dramatically after 36 months therapy with amlodipine. The IMT and endothelium-dependent vasodilative function came up to normal standards in group A and approached the normal level in group B. Conclusions Amlodipine can improve the endothelium-dependent vasodilative function, retard or even reverse the progression of carotid artery IMT, when it lowers blood pressure stably.
5.Evaluating about the effects of using health education for patients with family liquid transfusion
Chinese Journal of Practical Nursing 2006;0(15):-
Objective To make sure the effects of using health education for patients with family liquid transfusion. Methods Investigated 200 patients with family liquid transfusion by questionnaire, and then analyzed the datum which had obtained. Results In the different age group, the master rates of health knowledge were 94.62%, 90.75% and 85.00% before the health education. While, after the health education, the corresponding rates were 98.21%, 96.50% and 96.11%, the differences were significant,P
6.Guiding principles in developing community health service in the new century
Chinese Journal of Hospital Administration 1998;0(11):-
Community health service in the new century has entered a new stage of development. To ensure the healthy advancement of community health service in the course of system building, the following guiding principles must be adhered to: spurring on system innovation with concept innovation and giving full play to the staying power of community health service; taking the introduction of the competition mechanism as the soul and unremitting impetus of innovation; persisting in the solution of problems accompanying advance and development with methods promoting development; taking the strategic readjustment of health resources as the main line of development; taking the attainment of a favorable external environment as the impetus of development; and sticking to a path of coordinated growth that stresses both quality and speed.
7.Vigorously promoting reform of the medical health system and accelerating development of community health services
Chinese Journal of Hospital Administration 1996;0(02):-
A nationwide pilot project concerning community health sendees, the major part and chief link of the reform in the urban medical health system, has basically come to an end. The author expounds against the background of reform in the health system in China the motives and orientation of reform in the medical health system and the current situation of and problems in the development of community health services. It is pointed out that advancing community health services entails all of the following:①genuinely transforming concepts and seeking unity of thinking; ②adopting the mechanism of competition and enhancing the sense of innovation; ③persisting in keeping abreast of the times and laying emphasis on reform and development;④accelerating the readjustment of resources and optimizing resource allocation; ⑤ceating a sound environment and seeking common development; ⑥giving priority to the improvement of quality and avoiding superficial transformation.
8.Development of study on NMDA receptor with auditory plasticity and learning memory.
Jianhong LI ; Shuyu WANG ; Xiaoming LI
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2012;26(13):618-623
Neural plasticity is one of the most important research area of developmental neurobiology. NMDA(N-Methyl-D-aspartate) receptor is one of the glutamate receptors in nervous system, which palys an important role in many biological and pathological changes, such as development of neural network, neural plasticity, learning and memory, degeneration of the neurons and so on. The studies on NMDA receptor with auditory plasticity and learning and memory were reviewed in order to make early intervention for hearing impaired children and provide a theoretical basis.
Auditory Perception
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Humans
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Learning
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Memory
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Nervous System
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Neuronal Plasticity
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Receptors, N-Methyl-D-Aspartate
9.Isolated renal mucormycosis in children(report of 3 cases)
Jianhong LI ; Minghe WANG ; Fuyu LI
Chinese Journal of Urology 2001;0(07):-
Objective To investigate the clinical characteristics of isolated renal mucormycosis in children. Methods The clinical manifestations,CT,IVU and surgical findings of 3 children with isolated renal mucormycosis were analyzed. Results A three-month newborn presented asymptomatically except for renal mass.The other two children had fever,lumbar pain,hematuria,renal enlargement and tenderness.CT scan showed multiple low density foci in the kidneys.All of the three children underwent nephrectomy and systemic amphotericin B treatment,and the diagnoses were confirmed by pathological examination. Conclusions Isolated renal mucormycosis is a rare fungal infection without predisposing factors,and its clinical characteristics are different from the usual systemic mucormycosis.Early diagnosis,nephrectomy and systemic amphotericin B treatment are necessary for improving the prognosis.
10.Anatomic outcomes of scleral buckling or lens-sparing vitrectomy for stage 4 retinopathy of prematurity
Hong YIN ; Xiaoxin LI ; Jianhong LIANG
Chinese Journal of Ocular Fundus Diseases 2012;28(1):26-28
Objective To evaluate the anatomic outcome after lens-sparing vitrectomy (LSV) or scleral buckle (SB) for stage 4 retinopathy of prematurity (ROP).Methods The clinical data of 39 infants (50 eyes) with 4a (20 eyes) or 4b (30 eyes) were retrospectively analyzed.The age ranged from two to 18 months,with a mean of (6.0±3.4) months.The gestational age ranged from 26 to 33 weeks,with a mean of (30.0±1.6) weeks.The birth weight ranged from 800 to 1900 g,with a mean of (1404.5±237.6) g.Nineteen eyes underwent SB and 31 eyes underwent LSV.Follow-up ranged from 6 to 84 months,with a mean of (26.0±21.7) months.The anatomical and refractive results were reviewed at the final follow-up.Results The anatomic success of SB was 100.0% (19 of 19 eyes) and that of LSV was 87.1% (27 of 31eyes).Among the patients in whom treatment failed,4 were in the LSV group (4/31,12.9%).The buckles of 5 eyes (5/19,26.3%) were removed.At the end of the follow-up,the mean myopic refraction was (-4.46±2.49) diopters (ranging from -1.25 to 11.00 diopters) in the LSV group,and ( -3.21±1.96) diopters (ranging from -1.25 to 9.25 diopters) in the SB group.There was no significant difference between two groups (F=2.76,P=0.103).Conclusion The anatomic outcome after LSV or SB for stage 4 ROP was excellent.