1.Clinical Study on the Intervention of Gastric Compound for Patients with Middle-late Gastric Cancer of Spleen Deficiency and Stasis Toxin
Dongfang LI ; Jiangli FAN ; Yunqi WANG ; Zhenyang LIU ; Hui LIANG ; Yuming LI ; Min ZHOU ; Hong WU ; Jiao JIAO
Chinese Journal of Information on Traditional Chinese Medicine 2015;(3):20-23,24
Objective To evaluate the effect of gastric compound on patients with middle-late gastric cancer of spleen deficiency and stasis toxin. Methods Ninety patients with middle-late gastric cancer of spleen deficiency and stasis toxin were randomly divided into combined group, chemotherapy group, and gastric compound group, 30 cases in each group. Patients in the combined group were treated with gastric compound and chemotherapy;patients in the chemotherapy group were treated with placebo;patients in the gastric compound group were treated with gastric compound. The changes of QLQ-C30 scale integral, fatigue scale intergral, TCM symptom intergral, Karnofsky integral, and toxic and side effects of digestive tract and myelosuppression were observed to evaluate the effect of gastric compound on quality of life in patients. Results The changes of QLQ-C30 scale integral, fatigue scale intergral, TCM symptom intergral, Karnofsky intergal in combined group were better than those in chemotherapy group and gastric compound group, with statistical significance (P<0.05). The changes of fatigue scale intergral and TCM symptom intergral in gastric compound group were better than those in chemotherapy group, with statistical significance (P<0.05). The myelosuppression and toxic and side effects of digestive tract of combined group was lighter than those of chemotherapy group, with statistical significance (P<0.01). Conclusion Gastric compound combined with chemotherapy can improve quality of life in patients with middle-late gastric cancer of spleen deficiency and stasis toxin, and reduce myelosuppression and toxic and side effects of digestive tract.
2.The influence of different emotional states on attention control ability of college students
Yi LIU ; Shaolan ZHAO ; Jiangli JIAO
Chinese Journal of Behavioral Medicine and Brain Science 2023;32(10):923-927
Objective:To explore the influence of different emotional states on college students' attention control ability in single and dual attention control tasks.Methods:A total of 28 college students from Xinjiang Normal University were selected as participants, and emotional pictures were used to activate the positive, negative and neutral emotional states of the participants, and the integrated paradigm of " double-choice Oddball+ Stroop" was used to investigate their attention control ability in different emotional states. The experiment was designed by 3 (emotional states: neutral mood, positive emotion and negative emotion) × 4 (task types: baseline task, single response inhibition, single interference inhibition and double attention control task), and the E-prime software was used to record the participant's reaction time and error rate. SPSS 21.0 software was used to perform repeated measurement ANOVA on the reaction time and error rate of 28 participants.Results:The interaction between emotional state and task type was significant( F(6, 22)=2.70, P<0.05). The main effect of emotional state was not significant ( F(2, 26)=0.79, P=0.461). The main effect of task type was significant ( F(3, 25)=28.46, P<0.001). The differences in average reaction time between baseline tasks, single interference suppression tasks, single response suppression tasks, and dual attention control tasks were statistically significant (all P<0.001). Simple effect analysis showed that in the single response inhibition task, the reaction time in positive emotional state ((499.62±72.09) ms) and negative emotional state ((521.52±86.39) ms) were significantly longer than that in the neutral emotional state((475.43±76.38) ms, both P<0.05), and that in the negative emotional state was significantly longer than that in the positive emotional state ( P<0.05). There was no significant difference between emotional states in the baseline task, single interference suppression task, and double attention control task (all P>0.05). Conclusion:In the single attention control task, both positive and negative emotional states have emotional interference effect on the response inhibition ability of college students, and the interference effect of negative emotional state is more sighificant. In the dual attention control task, the emotional interference effect disappeared.