1.The role of heparin in the interventional therapy for thrombotic diseases
Journal of Interventional Radiology 2001;0(06):-
Objective To evaluate the role of heparin in treating thrombotic diseases by interventional radiology.Methods In order to perform general anticoagulation, heparin or small molecule heparin were used for patients with acute brain thrombosis in 22 cases, limb artery thrombosis in 18 cases, ilic and formal vein thrombosis in 200 cases, inferior vena cava thrombosis in 20 cases. All patients were treated by thrombolysis with UK, or placing filter in inferior vena cava simultaneously with heparin. Results Under general anticoagulation, the effects of thrombosis dissolution for artery were positive. After thrombolysis, heparin must be used to keep the vascular patency. The recanalization of iliac and formal veins was lower than that of artery. The effect of applying heparin combined with thrombolysis was better than that of thrombolysis alone. Conclusions During the course of therapy of thromobotic diseases application of heparin should be the first and their follow by thrombolysis that is the principle for interventional therapy.
2.Wireless sensor network in American War-fighter Physiologic Status Monitoring System
Chinese Medical Equipment Journal 2003;0(11):-
War-fighter Physiologic Status Monitoring(WPSM)is a wireless sensor network that is used to collect,transmit,store and interpret physiologic data from soldiers,sailors and pilots.It can collect and monitor information regarding vital signs such as body temperature,heart rate,blood pressure,hydration and stress levels,sleep status,body position and workload capacity of the warrior.If necessary,the WPSM can notify medics and commanders if the soldier has been wounded or has become fatigued.The structure of the wireless sensor network in the WPSM and the data management of the sensor network are mainly discussed.
3.Management of Drug Account in Emergency Pharmacy with Excel
China Pharmacy 2005;0(24):-
OBJECTIVE:To probe into the approach of managing drug account in emergency pharmacy by Excel.METHODS:Drug account in hospital emergency pharmacy was established by means of Excel,the drugs in the emergency pharmacy were kept under control by means of Excel’s multi-functions like searching,sorting,selecting statistics,etc.RES_ ULTS:Through excel,a clear shift records account of emergency pharmacy drugs was achieved,the recording and statistics of prescriptions become more convenient and fast,both the working efficiency and the congruity between the account and the drugs were greatly enhanced.CONCLUSION:Intelligentized management of emergency pharmacy drugs can be effectuated by means of Excel.
4.Construction of the eukaryotic expression vector of mouse 24p3 gene and its expression in NIH3T3 cell lines
Jianghong AN ; Jianxin ZHOU ; Bin CHEN
Journal of Third Military Medical University 2003;0(17):-
Objective To construct the eukaryotic expression vector of mouse 24p3 gene and express it in NIH3T3 fibroblast cell line and verify its biological function of delivering iron into cells. Methods 24p3cDNA was cloned by RT-PCR and the eukaryotic expression vector of mouse 24p3 gene was constructed by gene recombination technique and the recombinant plasmid was verified by restriction enzyme digestion analysis and sequenceing, then transfected into NIH3T3 cells using DOTAP transfection reagent. Then the positive clones were selected and amplified. The expression of 24p3 gene in the culture supernatant of positive clones was analyzed by ELISA and Western blotting and its biological activity of delivering iron into cells was tested by atomic absorption spectrometer. Results The eukaryotic expression vector was constructed successfully. The NIH3T3 cells that stably expressed 24p3 were screened out. 24p3/SIP24 protein could express in the culture supernatant of positive clones and deliver iron into NIH3T3 cells. Conclusion The 24p3 gene was expressed successfully in the transfected NIH3T3 cells with good biological activity, which laid the foundation for further studying its biological function and mechanism involved in the iron metabolism.
5.Effect of caffeic acid phenethyl ester on the growth of human colorectal carcinoma cell line HCT116 transplanted subcutaneously in nude mice
Debing XIANG ; Dong WANG ; Jianghong MOU
Medical Journal of Chinese People's Liberation Army 2001;0(11):-
Objective To investigate the effect of caffeic acid phenethyl ester (CAPE) on the growth of human colorectal carcinoma cell line HCT116 transplanted subcutaneously in nude mice. Methods Nude mouse model of human colorectal carcinoma by subcutaneous transplantation of HCT116 cell line was reproduced. A total of 20 mice were divided into 2 groups: control group and CAPE group (oral administration of CAPE at 5mg/mice/d). The growth of the subcutaneously transplanted tumor and changes in mouse body weight in each group after treatment were observed on 7, 14, 21 and 28d. Histopathological examination of xenograft, heart, liver, lung, kidney and intestine of nude mice was also conducted. Apoptosis index was detected by terminal dUTP nick end labeling (TUNEL) technique. Results CAPE had significantly inhibitory effect on growth of the transplanted xenograft in vivo. Tumor volume and tumor weight were decreased (P
6.The distribution characteristic of lymph vessel in colorectal carcinoma tissue and its relationship to metastasis and prognosis
Xiaochu YAN ; Jianghong MOU ; Fengxuan LIU
Journal of Third Military Medical University 2003;0(22):-
0.05),but the MLD values at the tumor margin were significantly higher than that of normal mucosa(P
7.Feature of VEGFR-3, podoplanin and CD34 positive vessels in colorectal cancer and their correlation with metastasis
Jianghong MU ; Debing XIANG ; Hualiang XIAO
Medical Journal of Chinese People's Liberation Army 1982;0(01):-
Objectives To study the characteristics of VEGFR-3, podoplanin or CD34 positive vessels in colorectal cancer (CRC) and their correlation with metastasis. Methods The characteristics of VEGFR-3, podoplanin or CD34 positive vessels in 96 cases with CRC and normal mucosa were evaluated by single-labeling or double-labeling immunohistochemistry with anti-human VEGFR-3, podoplanin or CD34 antibody respectively, and their relationship with metastasis of the cancer was analyzed. Results The density of VEGFR-3, podoplanin or CD34 positive vessels at the peripheral region of CRC was significantly higher than that of other regions of CRC or that in normal mucosa (P
8.DNA Damages in Peripheral Blood Lymphocytes Induced by Organic Extracts From Ambient Air Particulates With Various Diameters
Jianghong ZHANG ; Wenmin YANG ; Yanwu XU
Journal of Environment and Health 1992;0(02):-
Objective To explore the health effects of organic extracts from ambient air particulates with various diameters on the DNA damage of human peripheral blood lymphoctys. Methods Using a 5-stage air sampler, the ambient air particulats samples were collected in a residential area of Taiyuan city and were extracted with dichloromethane, acetone and methanol. The damage of DNA in human peripheral blood lymphocytes induced by organic extracts from ambient air particulates with various diameters at doses of 25, 50, 100 ,200 ?g/ml were detected by sigle cell gelelectrophoresis assay. Results The toxic efficiency of organic extraction of ambient air particulates increased with the decreases of the diameters of particulates. The tail lengthes of the comets induced by organic extracts from ambient air particulcctes with various diameters
9.Clinical observation and efficacy on lumbar interbody fusion for spine pelvic sagittal balance
Jianghong LUO ; Wei LI ; Tingsheng LU
Journal of Regional Anatomy and Operative Surgery 2015;(4):408-410
Objective To analyze the clinical therapeutic effect of lumbar fusion in the treatment of lumbar degenerative diseases in the spine pelvic sagittal balance. Methods From June 2009 to June 2012,the clinical data of 92 cases with lumbar degenerative diseases ac-cepted lumbar spinal fusion operation in our hospital was collected. The contrast lumbar lordosis ( LL) ,lumbar sagittal vertical axis ( SVA) , pelvic incidence angle ( PI) ,sacral inclination angle ( SS) ,pelvic tilt angle ( PT) and other numerical parameters,using the Oswestry disabil-ity index ( ODI) ,visual analogue scale ( VAS) and the Japan Society of Department of orthopedics ( JOA) score were followed up two years after operation,and the postoperative effect was evaluated. Results The spinal pelvic parameters SVA,LL,SS and PT after surgery were changed obviously,and the difference was statistically significant(P<0. 05). The postoperative follow-up of VAS,ODI and JOA score were better than that of preoperation,the difference was significant(P<0. 05). Conclusion Lumbar fusion operation can restore lumbar lordosis, to maintain the spine pelvic sagittal balance and improve the effect of operation,and have positive significance to improve the postoperative symptoms.
10.Accelerated pace of clinical paths to optimize key medical service processes
Haixiao CHEN ; Jianghong ZHU ; Yaohui WANG
Chinese Journal of Hospital Administration 2010;26(7):492-495
The key to clinical paths administration lies in the optimization of the key processes and sectors in medical service, which will achieve an integration that is based on patients and span departments to cover all medical service sectors and processes. The clinical path practice was introduced into the hospital in 2005, and the clinical paths have been put into practice for over 20,000 cases/occasions by the end of 2009, scoring satisfactory social and economic outcomes as of now. For the purposes of speeding up the clinical path practice for expected outcomes in optimizing key medical service processes, we have got the following eight experiences and lessons: (1) Build shared demands; (2)Establish a powerful leadership; (3) Develop and promote visions; (4) Eliminate resistance and pool the forces; (5) Keep on the efforts and focus on details; (6) Reward involvements; (7) Recruit and develop key operators within the hospital; (8) Systemize and supervise the experiences of implementation.Promotion of clinical paths is a renovation in management with its inherent rules. Adoption of appropriate technical strategies and cultural strategies will upgrade the quality and acceptance of clinical path implementation.