This study examined the clinical features of complications of congenital retinoschisis and the clinical efficacy of vitreoretinal surgery in the treatment of these complications. The clinical efficacy of surgical treatments was retrospectively analyzed in 10 patients with congenital retinoschisis (10 eyes) complicated with rhegmatogenous retinal detachment (n=5), vitreous hemorrhage (n=2) and macula- involving schisis (n=1). All the patients suffered foveal and peripheral schisis. They were treated with scleral buckling (n=1) or vitrectomy (n=9). After the surgical treatment, the retina was reattached in patients with rhegmatogenous retinal detachment; the refractive media became transparent in those with vitreous hemorrhage; the visual acuity in 80% of patients was improved; no remarkable progression of schisis was found; no severe operative complications occurred. It was concluded that vitreoretinal surgery in the treatment of complications of congenital retinoschisis is safe and effective, and helps improve and maintain the visual function.

With growing number of operation with congenital heart disease ( CHD) ,its methods of treatment are paid more and more attention by the surgeons .The article briefly introduced the concept ,development history ,the main clinical applications ,complica-tions,treatment, comprehensive evaluation and prospect of hybrid approach.

0.05).CD3~+,CD4~+,CD4~+/ CD8~+ in A group on the 8th day were higher(P0.05) than those on the 1st day.Compared to B group,CD3~+,CD4~+,CD4~+/ CD8~+ in A group on the 8th day were increased significantly(P

OBJECTIVE:To explore the mode,methods and role of clinical pharmacists providing pharmaceutical care for pa-tients with natural killer/T-cell lymphoma (NK/TL) complicated with diabetes. METHODS:Clinical pharmacists participated in SMILE chemotherapy plan for a NK/TL patients with diabetes mellitus,evaluated potential chemotherapy risk during first chemo-therapy,implemented individual medication monitoring and put forward suggestion. It included insulin injection 4 U,ivgtt,to con-trol the increase of blood glucose induced by dexamethasone;sodium bicarbonate 40 ml,ivgtt,bid to alkalize urine;allopurinol 0.1 g,po,tid to inhibit uric acid;fluid infusion 4 000 ml/d to prevent renal failure;mesna 0.4 g/time to protect urinary passage;monitorring potential allergic reaction and arrest of bone marrow;providing medication education on the application of calcium foli-nate in SMILE chemotherapy regimen. RESULTS:Physicians adopted the suggestions of clinical pharmacist,and chemotherapy was carried out smoothly. No ADR was found,and patients manifested good medication compliance. CONCLUSIONS:Clinical pharmacists participate in chemotherapy,evaluate potential risk and provide individual medication monitoring,which optimize ther-apy plan,reduce medication risk and guarantee the safety of drug use.

Antibodies ; immunology ; Graft Rejection ; drug therapy ; immunology ; prevention & control ; Graft Survival ; immunology ; Humans

A comparison of plant and animal stem cells can highlight core aspects of stem-cell biology. In both kingdoms, stem cells are defined by their clonogenic properties and are maintained by intercellular signals. The signaling molecules are different in plants and animals stem cell niches, but the roles of argonaute and polycomb group proteins suggest that there are some molecular similarities.
Animals ; Plant Cells ; Signal Transduction ; Stem Cells ; cytology ; metabolism

Objective To investigate the sensitivity of different methods in the diagnosis of portal hypertension associated with liver cirrhosis. Methods 99 patients with portal hypertension associated liver cirrhosis, and 49 healthy subjects as control were enrolled in this study. Their portal and splenic vein widths, and the conditions of varicose vein in esophagus and gastric fundus were determined, and portal pressures were measured by radionuclide method. The positive percentage of different methods for the diagnosis of portal hypertension were analysed. Results Most of the patients with portal hypertension had the extension of portal and splenic vein in the fifferent areas and in various degrees. There were no significant differences in the degrees of portal and splenic vein extension among the patients with mild, moderate or severe esophageal varicose vein. The width of portal and splenic vein was not related with portal pressure. Radionuclide method was the most sensitive in diagnosing portal hypertension. Conclusion Portal hypertension can be diagnosed according to the conditions of vessels and spleen. The sensitivity of different methods in diagnosing portal hypertension were different, and that of radionuclide method was the highest. The width of portal and splenic vein had no close relation with portal pressure and the degree of esophageal varicose vein.

Understanding of the classification of intracerebral hemorrhage may help to better manage the patients with intracerebral hemorrhage.Selecting the appropriate diagnosis and treatment measures as well as preventive strategies for different subtypes in order to improve the prognosis of intracerebral hemorrhage and prevent the recurrence.This article reviews the present common classification methods of intracerebral hemorrhage studied and reported in the world.

Objective To compare the efficacy of Lichtenstein and transabdominal preperitoneal patch repair(TAPP) in the treatment of primary inguinal hernia in adults. Methods The clinical data of 223 patients who received Lichtenste and 121 patients who underwent TAPP in our hospital between January 2002 and January 2006,were analyzed retrospectively.The efficacy and complications of the two methods were compared.Results The rate of intraoperative injury of the inner organs in the TAPP group was significantly higher than that in the Lichtenstein group [5.8%(7/121) vs 0.4%(1/223),?2=7.626,P=0.006],while no significant difference was detected in the rate of abdominal organ injury between the two groups [0.8%(1/121) vs 3.1%(7/223),?2=0.969,P=0.325].The rate of postoperative complications in the TAPP group was significantly lower than that in the Lichtenstein group [14.0%(17/121) vs 36.3%(81/223),?2=18.881,P=0.000].In the TAPP group,during a follow-up of(14?7) months,one case of recurrence was found(0.8%).Whereas in the Lichtenstein group,the patients were followed up for(16?8) months,two of them had recurrence(0.9%).No significant difference existed in the recurrence rate between the two groups(?2=0.000,P=1.000).Conclusions Both the Lichtenstein and TAPP have benefits and drawbacks.Individulized therapy is recommended for the patients with inguinal hernia.It is important for surgeons to know the indications of the operations.

Objective To investigate the clinical features of patients with neuromyelitisoptica spectrum disorders (NMOSD) in China.Methods Cases reports of NMOSD from 1989 to 2016 were retrieved from the database of Weipu data basis,and the clinical features of cases reported were analyzed.Results Eighty-seven studies were enrolled.Totally 109 patients were included.The ratio of male to female was 1 ∶ 4 and the mean onset age was (38.44 ± 17.08) years (range 5-76 years).The predisposing factors was catching a cold(12.80％).There were 66.05％ patients with optic neuritis symptoms as initial symptoms,23.85％ with spinal cord inflammation as the first symptom.Spinal magnetic resonance showed that 80.73％ of the lesions involved thoracic spinal cord,and the cervical spinal cord occupied by 49.54％,while the lumbar spine accounted for about 10.09％.12.84％ involved the final area.Conclusion In China,NMSOD is common in young adults,and more common in women.The onset age between the male and female has no significant difference.The first symptom of optic neuritis is more common,and the spinal cord lesion in thoracic cord is popular.