1.Cone-Beam CT evaluation of upper airway following rapid maxillary expansion and maxillary protraction for the treatment of skeletal class Ⅲ malocclusion
Hongwei WANG ; Suqing QI ; Chao ZHANG ; Sufeng REN ; Hongwei HUI ; Lei LI ; Jiandong BAN
Journal of Practical Stomatology 2016;32(4):532-536
Objective:To analyze the 3D changes of pharyngeal airway in patients with skeletal Class Ⅲ malocclusion after rapid maxillary expansion(RME)and maxillary protraction.Methods:53 patients underwent orthodontic treatment with Hyrax palatal ex-panders and maxillary protraction.Cone-Beam computed tomography(CBCT)scan was taken before treatment(T0),after 1 6 d RME (T1 )and after about 5 month maxillary protraction(T2).Data were reconstructed into 3D model,sagittal and transversal measure-ments,cross sectional areas,volumes of the pharyngeal airway were computed.Results:After RME,the transversal measurements, cross sectional areas,volumes of nasal passage were increased(P <0.05).After maxillary protraction,the 4 nasopharyngeal measure-ments were increased(P <0.05).Conclusion:RME and maxillary protraction may increase pharyngonasal airway.
2.Three-rooted unilateral maxillary first premolar diagnosed by CBCT:A case report
Yan HOU ; Jiandong BAN ; Junke LI ; Xiaolan MA ; Hongwei WANG ; Wei YUAN ; Ruijuan MU ; Lizhen MA
Journal of Practical Stomatology 2015;(6):875-876
Most of the maxillary first premolar are single-rooted,there are also two-rooted and three-rooted ones.A case of three-rooted maxillary first premolar was diagnosed by CBCT.CBCT has the advantage in the observation of the variation root number,root canal bending and the variation of root canal morphology.
3.Study on the Anti-coagulation Effect and Mechanism of Fibrinolytic Enzyme SNFE in Sipuculus Nudus
Yingxin LI ; Xiaoliang HUANG ; Yuanheng HUANG ; Jiandong BAN ; Lijun PANG ; Qinrong LI ; Danqing LEI
China Pharmacy 2017;28(28):3938-3941
OBJECTIVE:To study the anti-coagulation effect and mechanism of fibrinolytic enzyme SNFE in sipuculus nudus, and provide reference for further development of SNFE. METHODS:40 mice were randomly divided into blank control group(nor-mal saline),Xueshuantong group(positive control,15 mg/kg)and SNFE low-dose,high-dose group(15,30 mg/kg),10 in each group. After intravenous injection in tail,tail bleeding time (BT) and clotting time (CT) were respectively determined to investi-gate the anti-coagulation effect of SNFE. After taking blood in abdominal aorta of rats,test was divided into blank control group, positive control group and SNFE low-mass concentration,medium-mass concentration,high-mass concentration groups (0.25, 0.50,1.00 mg/mL). Prothrombin time(PT),re-calcium time(PRT)(using orokinase as positive drug,100000 U/mL),and max-mum platelet aggregation rate (PAG) in 5 min under adenosine diphosphate (ADP) inducer (using asprin as positive drug,0.50 mg/mL) were respectively determined,and anti-coagulation effect mechanism of SNFE was analyzed. RESULTS:Compared with blank control group,BT,CT of mice in each group were prolonged,with statistical significance in Xueshuantong group and SNFE high-dose group (P<0.05 or P<0.01). Plasma PT of rats in positive control group,SNFE medium-dose,high-dose groups and PRT in each administration group were significantly prolonged(P<0.05 or P<0.01);and PAG in administration group was signifi-cantly reduced(P<0.01). CONCLUSIONS:The fibrinolytic enzyme SNFE in sipuculus nudus can play its anti-coagulant effect by inhibiting the activity of coagulation factors in internal and external sources and ADP-induced platelet aggregation.
4.Cone-beam CT evaluation of nasomaxillary complex and upper airway following rapid maxillary expansion.
Lei LI ; Suqing QI ; Email: QSQ7615038@163.COM. ; Hongwei WANG ; Sufeng REN ; Jiandong BAN
Chinese Journal of Stomatology 2015;50(7):403-407
OBJECTIVESTo evaluate the naso-maxillary complex width and pharyngeal airway volume changes after rapid maxillary expansion (RME).
METHODSThirty-five patients were selected (18 males, 17 females, mean age, 12.1 ± 1.1 years). All patients underwent orthodontic treatment with Hyrax palatal expanders. Cone-beam CT (CBCT) scan was taken before treatment (T0), 16 days (T1) and three months (T3) after RME. Naso-maxillary complex width and pharyngeal airway volume were measured.
RESULTSAfter treatment the width of piriform aperture and maxillary width were significantly increased compared with that before treatment (P < 0.05). Three months after RME, no statistical difference was found in maxillary width compared with that before treatment. The nasopharyngeal volume significantly increased by 29.9% compared with that before treatment (P < 0.05), and the volume remained relatively stable after three months.
CONCLUSIONSRME resulted in a significant increase in the naso-maxillary complex width and nasopharyngeal volume.
Cone-Beam Computed Tomography ; Female ; Humans ; Imaging, Three-Dimensional ; Male ; Maxilla ; diagnostic imaging ; Nose ; diagnostic imaging ; Palatal Expansion Technique ; Palate ; diagnostic imaging ; Pharynx ; diagnostic imaging