1.Clinical significance of serum cystatin C and urinary TGFβ1 in severe eclampsism
International Journal of Laboratory Medicine 2008;29(8):693-694
Objective To investigate the clinical value of surem eystatin C and urinary transforming growth factorβ1(TGF-β1)in patients with severe eclampsism.Methods Serum cystatin C and urinary transforming growth factorβ1 were examined in 35 severe eclampsism women(experiment group,n=35)and normal late pregnant women(control group,n=35).Results The levels of serum cystatin C and urinary transforming growth factorβ1 were both significantly increased in experiment group than those in control group(both P<0.01).The serum level of cystatin C was positively correlative with urinary TGF-β1 level in experiment group(r=0.581,P<0.05).Conclusion The detection of serum cystatin C and urinary transforming growth factorβ1 is useful to assess renal function lesion in patients with severe eclampsism,which contributes to the diagnosis and treatment of severe eclampsism.
2.Nuclear Factor-κB,Tumor Necrosis Factor-α and Cerebral Infarction
International Journal of Cerebrovascular Diseases 2008;16(6):469-472
Nuclear factor-κB(NF-κB),a transcription factor,which widely exists in neuron,neuroglial cell and vascular endothelial cell.It mainly participates in the inflammatory reaction,apoptosis,immunological reaction and other stress reaction of the body.It is considered as an initiation factot of vascular endothelial cell injury.Cytokines.such as tumor necrosis factor-α may promote the inflammatory cascade reaction in cerebral infarction,and may also play an important role in cerebral ischemic injury.
3.Guidance value of multi-slice computed tomography in D2 radicaltotal gastrectomy for gastric cancer
Journal of Practical Radiology 2015;(10):1628-1630,1634
Objective To evaluate the application value of multi-slice spiral CT(MSCT)in D2 radical total gastrectomy for gastric carcinoma.Methods CT and clinical data of 353 cases with D2 radical total gastrectomy for gastric carcinoma was analyzed retro-spectively.Results Operative time was 236 (1 91-35 1)mins VS.245 (189-308)mins,no significant difference was observed be-tween the CT scan group and the non-CT scan group(P >0.05).The number of lymph nodes dissected was (27 ±3)VS.(20±2), there was significant difference between the CT group and the non-CT group (P <0.05).The blood loss in the CT group and no CT group was less 168 (110-600)mL and 280 (150-720)mL respectively(P<0.01).Postoperative hospital stay was shorter (11.2±2.1)days in CT group than no CT group (14.5±2.0)days (P <0.01).Postoperative complications developed in 1 7 patients in the CT group and in 29 patients in the non-CT group.The difference didn’t show statistically significant between the two groups (P >0.05).Conclusion Multi-slice computed tomography scanning has a great value in D2 radical total gastrectomy for gastric carcinoma.
4.Why should rhinologic doctor pay attention to the lower respiratory tract of chronic rhinosinusitis patients?.
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2015;29(5):478-482
The purpose of this review is to explain the relationship between chronic rhinosinusitis (CRS) and lower respiratory tract inflammation, especially asthma and introduce the new advances in the treatment of CRS patient with asthma. We also introduce our treatment strategy for these patients, including surgery technique and perioperative management.
Asthma
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pathology
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Chronic Disease
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Humans
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Inflammation
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pathology
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Otolaryngology
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methods
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Respiratory System
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physiopathology
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Sinusitis
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physiopathology
6.Investigation of Microcystin in Tai Lake Water and Fish
Jianbo YANG ; Yan CHEN ; Yudi LIN
Journal of Environment and Health 1993;0(01):-
Objective To know the pollution situation by microcystin MC in Tai Lake in Wuxi. Methods The MC content in 12 water samples and 28 fish samples in the Tai Lake were determined by ELISA. Results The positive rates of MC in water samples and fish samples were 100%. The mean content of MC in water samples was higher in July 9 874.8 pg/ml than in November 142.8 pg/ml. The mean content of MC in the livers was 27.84 ng/g, in the muscle it was 3.97 ng/g. Conclusion The Tai Lake has been contaminated by microcystin and it can be detected in the fish living in the lake.
7.Observations on the Efficacy of Electroacupuncture plus Acupoint Application in Treating Diabetic Constipation
Jianbo WANG ; Jingjing XUE ; Weiwei CHEN
Shanghai Journal of Acupuncture and Moxibustion 2016;35(9):1077-1080
Objective To investigate the clinical efficacy of electroacupuncture plus acupoint application in treating diabetic constipation of yin deficiency and blood stasis type.Methods One hundred and fifty-six patients with diabetic constipation of yin deficiency and blood stasis type were randomly allocated to treatment and control groups, 78 cases each. The treatment group received electroacupuncture plus acupoint application and the control group, oral administration of mosapride citrate tablets. The TCM syndrome scores were recorded in the two groups before and after treatment. The clinical therapeutic effects were evaluated using the Constipation Scoring System (CSS), the Patient Assessment of Constipation Quality of Life (PAC-QOL) questionnaire and the TCM syndrome scores.Results There was a statistically significant post-treatment difference in the total efficacy rate based on CSS, PAC-QOL and the TCM syndrome scores between the two groups (P<0.05,P<0.01). There were statistically significant pre-/post-treatment differences in the TCM syndrome scores in the treatment group (P<0.05). There were statistically significant pre-/post-treatment differences in TCM syndrome dry mouth and tongue, thirst and dry stool scores in the control group (P<0.05). There were statistically significant post-treatment differences in TCM syndrome short breath, weakness, lassitude, stabbing pain, scaly dry skin, fixed pain, sore and weak loins and knees, and chest, palm and sole vexing heat scores between the two groups (P<0.01,P<0.05).Conclusion Electroacupuncture plus acupoint application is an effective way to treat diabetic constipation of yin deficiency and blood stasis type.
8.Observation on the treatment of psoriasis vulgaris with narrow-band ultraviolet B and traditional Chinese medicine fumigating
Hong CHEN ; Jianbo ZHANG ; Jingai WEN
International Journal of Traditional Chinese Medicine 2010;32(3):249,258-
Objective To observe the treatment of psoriasis vulgaris with narrow-band ultraviolet B and self-made traditional Chinese medicine fumigating.Methods A total of 100 patients with psoriasis vulgaris were randomly recruited into a treatment group and a control group,50 patients in each group.The control group was treated with narrow-band ultraviolet B:on this basis,the treatment group was treated with self-made traditional Chinese medicine fumigating.The therapeutic effeCts of both groups were observed.Results As compared with the control group.the treatment group showed better therapeutic effects(P<0.05).Conclusion It was effective to treat psoriasis vulgaris with narrow-band ultraviolet B combined with self-made traditional Chinese medicine fumigating.
9.The effects of senile osteoporosis on fracture healing
Jianbo HAN ; Meng CHEN ; Shufeng LI
Clinical Medicine of China 2011;27(12):1308-1310
Objective To explore the fraction risk in patients with osteoporosis and effects of antiosteoporosis therapy on fracture healing.Methods All the recruited subjects were senile patients with fracture in lower extremity and were treated in the Department of Orthopaedics in Shandong Qianfoshan Hospital from Aug.2006 to Feb.2011.In the total 15 cases,10 were female and 5 were male,aged from 53 to 65 years (average 56.7 years old).After surgical reduction and internal fixation,all the 15 patients did free-weight and continous passive motion (CPM) functional exercise and received anti-osteoporosis treatment.X-ray was taken to show the preoperative and postoperative lumbar vertebrae and fracture position.Meanwhile,bone mineral density and blood calcium level and phosphate level were measured.Results Thirteen out of 15 patients were healed for bone fracture after a 3-month treatment,meeting the clinical standards of the fracture healing.The clinical fracture healing rate was 86.67%.Blood calcium level,phosphate level and the bone mineral density were significantly different between that before and after the treatment ( P < 0.05 ).Conclusion Osteoporosis not only increases the risk of fracture,but also has an adverse effect on the bone healing.Anti-osteoporosis therapy has a positive role to the fracture healing in the senile patients with osteoporosis.
10.Clinical Value of Intra-abdominal fluid Monitoring after Laparoscopic Splenectomy
Chunlin LI ; Sirui CHEN ; Jianbo LI
Chinese Journal of Minimally Invasive Surgery 2001;0(04):-
Objective To investigate the approaches and clinical value of intra-abdominal fluid monitoring after laparoscopic splenectomy (LS). Methods We collected the data of 63 cases of LS performed in the West China Hospital from November 2005 to August 2008,and analyzed the level of amylase in intra-abdominal fluid,changes of color,volume,and characteristics of the drainage fluid,as well as the results of germiculture and ultrasonography. Results Among the cases,post-LS complications were detected by intra-abdominal fluid monitoring in 4 cases early after the surgery. In the four cases,2 patients showed hemorrhagic fluid (over 40 ml/h),and then was found having postoperative bleeding in the splenogastric ligament by abdominal exploration in 12 hours. In the other 2 patients,ravidous drainage fluid was detected in 6 days after the operation,and increased levels of amylase (15 189 and 9206 U/L,respectively) was revealed while germiculture was negative; pancreatic fistula (PF) was then diagnosed and somatostatin was administered. Of the 2 patients who developed PF,intra-abdominal drainage was patent in 1,and the drainage tube was withdrawn in 20 days; for the other cases who had non-patent drainage,ultrasonography-guided percutaneous puncture catheter drainage was performed,and the drainage tube was taken out in 2 months. Conclusions LS is safe,reliable,and minimally invasive. Postoperative monitoring of intra-abdominal fluid is valuable for early detection of post-LS complications.