1.Curative Effect Observation of Transfer Factor Oral Solutions as Adjunctive Therapy in Elderly Patients with Recurrent Respiratory Tract Infection (RRTI)
China Pharmacist 2014;(2):260-261
Objective:To observe the curative effect of transfer factor oral solutions as the adjunctive therapy in ederly patients with recurrent respiratory tract infection ( RRTI) . Methods:Totally 74 ederly patients with RRTI were selected and divided into the observation group and the control group randomly. The patients in the two groups were given anti-infection and symptomatic treatment during the acute stage of attack. The patients in the observation group were additionally given transfer factor oral solutions 10ml, po, tid for 3 months. The changes in serum immunoglobulin IgG, IgA and IgM levels in the two groups before and after the medical treat-ment were compared, and the clinical curative effect and adverse drug reactions ( ADR) were observed as well. Results: After the medical treatment, the serum IgG, IgA and IgM levels in the observation group were obviously increased than before (P<0.05), while those in the control group showed no obvious changes (P>0. 05). The total clinical efficiency in the observation group was much higher than that in the control group (P<0. 01). The ADR between the two groups with light symptoms showed no statistical differ-ences (P>0. 05). Conclusion:Transfer factor oral solutions as the adjunctive therapy in ederly patients with RRTI has the favorable clinical curative effect and safety, and the underlying mechanisms may be concerned with the effect of enhancing serum immunoglobulin IgG, IgA and IgM levels, as well as humoral immune function.
3.Comparison between CR and DR
Chinese Medical Equipment Journal 2003;0(10):-
Objectine To study the performance between CR and DR equipments. Methods To compare chest x-ray between the CR and DR equipment. Results The pathological detection with DR equipment is 20% higher than that with CR. Conclusion The quantity of information of DR is higher than CR.
4.The effect of intensive insulin therapy on cerebral infarction combined with hyperglycemia:a report of 70 cases
Chinese Journal of Postgraduates of Medicine 2014;37(1):17-20
Objective To investigate the effect and prognosis of intensive insulin therapy on cerebral infarction combined with hyperglycemia.Methods Seventy cases of cerebral infarction combined with hyperglycemia were divided into two groups by random number table method.Thirty-five cases in control group,were treated with insulin,and the blood glucose was controlled < 11.1 mmol/L; 35 cases in intensive group,were treated by insulin pump,and the blood glucose was controlled in 4.4-8.3 mmol/L.The degree of neurological damage and improvement of daily life in two groups before and after treatment was compared by National Institutes of Health Stroke Scale(NIHSS) and modified Rankin Scale(mRS) scores.Insulin dosage,the time for reaching the standard,incidence of hypoglycemia,pulmonary infection rate and fatality rate was recorded in two groups.Results The NIHSS and mRS scores between two groups before treatment had no statistical significance (P > 0.05),and after 30 d treatment,the NIHSS and mRS scores in control group [(8.29 ±2.74),(2.96 ±0.74) scores] and intensive group [(6.83 ±3.16),(2.02 ±0.62) scores] were obviously improved compared with those before treatment,and the improvement in intensive group was better than that in control group (P< 0.05).In intensive group,the insulin dosage and the time for reaching the standard was less than that in control group [(36.40 ± 6.91) U/d vs.(51.70 ± 9.86) U/d,(4.30 ± 0.87)d vs.(6.60 ± 1.24) d],incidence of hypoglycemia and fatality rate was lower than that in control group[5.7% (2/35) vs.25.7% (9/35),0 vs.8.6% (3/35)],the difference was statisticly significant (P < 0.05),but the pulmonary infection rate between two groups had no statisticly difference (P > 0.05).Conclusion The curative effect of intensive insulin therapy on cerebral infarction combined with hyperglycemia is better,and is helpful to the neural functional recovery.
5.Effect of blood glucose control level on prognosis in cerebral infarction with stress hyperglycemia
Chinese Journal of Postgraduates of Medicine 2013;36(34):4-6
Objective To analyze the effect of blood glucose control level on prognosis in cerebral infarction with stress hyperglycemia.Methods Ninety-two cases of new cerebral infarction within 24 h with stress hyperglycemia were divided into control group (46 cases) and observation group (46 cases).The blood glucose was controlled in 4.0-6.0 mmol/L in control group and 6.1-8.3 mmol/L in observation group.The hypoglycemia rate,infection rate,fatality rate,NIHSS score and Barthel score was observed in two groups.Results In control group,there were 14 cases cured,19 cases significantly improved,12 cases improved and 1 case invalid,while in observation group,there were 11,17,15,3 cases respectively,and the difference was not statisticly significant (P > 0.05).The hypoglycemia rate,infection rate,fatality rate was 19.6%(9/46),10.9%(5/46) and 2.2%(1/46) respectively in control group,while in observation group was 4.3% (2/46),15.2% (7/46) and 4.3% (2/46) respectively.The hypoglycemia rate was different between two groups(P < 0.05),but the infection rate and fatality rate was not statistic difference between two groups(P >0.05).The NIHSS and Barthel score was not different between two groups before treatment (P > 0.05).In control group the NIHSS after 1 week and 30 days after treatment and Barthel score 30 days after treatment was (15.47 ± 7.78),(9.85 ± 6.47),(67.18 ± 20.24) scores respectively,in observed group was (16.01 ±7.49),(10.17 ±5.84),(65.82 ± 19.93) scores respectively,which was improved compared with that pretreatment,but there was no significant difference between two groups(P > 0.05).Conclusion The blood glucose controlled in 6.1-8.3 mmol/L does not increase the infection rate and fatality rate,but can reduce the hypoglycemia rate and promote neural function recovery in cerebral infarction with stress hyperglycemia.
6.Classification of Etiology Theory in TCM Based on Concept of Unification of Human and Nature
China Journal of Traditional Chinese Medicine and Pharmacy 2005;0(07):-
This article expounds the formation,connotation and development of the etiology theory in TCM.By analyzing the deficiency of the existent etiology theory in TCM,we proposed that the essence of the etiology theory in TCM should be studied based on the concept of unification of human and nature.With the guidance of the concept of unification of human and nature,the etiology theory in TCM could be formed an integrated theory.The classification of etiology in TCM which includes basic etiology,secondum etiology and developing etiology was proposed,which makes the etiology theory system in TCM more scientific and logical.
7.Therapeutic Evaluation of Traditional Chinese Medicine Combined with Western Medicine for Pulmonary Embolism:An Observation of 16 Cases
Journal of Guangzhou University of Traditional Chinese Medicine 2001;0(03):-
0.05).But in the reported 6 groups patients,the fatality rate in 5 groups was higher that in the 16 patients,and the difference(P
8.Therapeutic Effect of Spleen-strengthening,Lung-clearing and Phlegm-resolving Therapy for Chronic Obstrustive Pulmonary Disease Complicated with Systemic Inflammatory Response Syndrome and Its Influence on Nuclear Factor ?B Expression
Journal of Guangzhou University of Traditional Chinese Medicine 1999;0(02):-
Objective To investigate the therapeutic effect of spleen-strengthening,lung-clearing and phlegm-resolving herbs for the treatment of acute attack of chronic obstrustive pulmonary disease(COPD) complicated with systemic inflammatory response syndrome(SIRS),and to observe their effect on nuclear factor ?B(NF-?B)expression level.Methods Sixty qualified patients differentiated as deficiency of spleen and lung,phlegm-heat accumulating the lung were equally randomized into two groups:the control group received routine western medical treatment including oxygen inhalation,antibiotics and bronchodilator,and the treatment group received Chen Xia Liujunzi Decoction and Weijing Decoction,which have the actions of strengthening spleen,clearing lung,and resolving phlegm,one dose per day,for 7 days.The changes of clinical symptoms and signs,blood gas parameters and NF-?B expression level were observed.Results After treatment,clinical symptoms and signs such as cough,expectoration,dyspnea,shortness of breath,and wheeze were relieved in both groups(P
9.The relationship between blood homocystei-e concentration in diabetic retinopathy patients and vas-cular endothelial cell damage and platelet activation
Journal of Chinese Physician 2008;10(8):1048-1050
Objective To analysis the relationship between blood homocysteine concentration in diabetic retinopathy patients with vascular endothelial cell damage and platelet activation.Methods 80 type 2 diabetes mellitus(T2DM)patients,including 50 no diabetic retinopathy(NDR group)and 30 diabetic retinopathy(DR group)and 30 normal controls were selected to measure the concentration of Hcy as well as circulating endothelial cells(CEC),Endothelin(ET),Yon Willebrand(vWF)and platelet activation markers CD62p and CD63.Results The level of CEC,ET,vWF,CD62p,CD63 and Hcy in T2DM group were,distinctly higher than those of control(P<0.01),furthermore,the level of these markers in DR group were also higher than that in NDR group(P<0.01).Blood CEC level Was positively related with ET(r=0.839,P<0.05),and the same relationship was found in Hcy and CEC(r=0.615,P<0.05),ET(r=0.642,P<0.05),CD62p(r=0.623,P<0.05)and CD63(r=0.542,P<0.05).Conclusions High blood Hcy,CEC,ET,vWF,CD62p and CD63 level were tighdy related with DR.High level of Hcy,vascular endMermis cell damage and platelet activation maybe play an important role in the pathogenesis of DR.
10.Effects of acupuncture of acupoints selected on postsurgical gastrointestinal dysfunction in patients undergoing non-gastrointestinal abdominal surgery
Chinese Journal of Anesthesiology 2016;36(3):267-271
Objective To evaluate the effects of acupuncture of acupoints selected on postsurgical gastrointestinal dysfunction in the patients undergoing non-gastrointestinal abdominal surgery.Methods A total of 160 patients of both sexes,aged 18-64 yr,of American Society of Anesthesiologists physical status Ⅰ or Ⅱ,scheduled for elective non-gastrointestinal abdominal surgery under general anesthesia,were randomly divided into 4 groups (n =40 each) using a random number table:control group (group C),common acupuncture group (group CA),acupuncture of acupoints selected group (group SA),and acupuncture of non-acupoint group (group NA).Acupuncture was performed at 30 min before induction of anesthesia in CA,SA and NA groups.Group CA received acupuncture at bilateral Taichong and Neiguan acupoints,group SA at bilateral Zusanli and Hegu acupoints,and group NA at the points 1 cm lateral to the acupoints of Zusanli and Hegu once every 30 min until the end of surgery.The time when the patients passed flatus,defecating time,and recovery time of bowel sounds were recorded after surgery.The occurrence of nausea and vomiting was recorded within 1 day after surgery.The electrogastrogram (EGG)was performed at 1 day before surgery and 2 days after surgery,and the frequency,amplitude and rhythm of EGG were recorded.At 1 day before and after surgery,the levels of plasma motilin and gastrin were determined using enzyme-linked immunosorbent assay.The recovery of postsurgical gastrointestinal function was assessed,and the recovery rate was calculated.Results Compared with group C,the incidence of postsurgical nausea and vomiting was significantly decreased,the time when the patients passed flatus,defecating time,and recovery time of bowel sounds after surgery were significantly shortened,the recovery rate was significantly increased,the frequency,amplitude and rhythm of EGG were significantly increased at 2 days after surgery,and the levels of plasma motilin and gastrin were significantly increased at 1 day after surgery in CA and SA groups (P<0.05).Compared with group CA,the incidence of postsurgical nausea and vomiting was significandy decreased,the time when the patients passed flatus,defecating time,and recovery time of bowel sounds after surgery were significantly shortened,the recovery rate was significantly increased,the frequency,amplitude and rhythm of EGG were significantly increased at 2 days after surgery,and the levels of plasma motilin and gastrin were significantly increased at 1 day after surgery in group SA (P< 0.05).Conclusion Acupuncture of acupoints selected provides better efficacy than common acupuncture in improving postsurgical gastrointestinal dysfunction in the patients undergoing nongastrointestinal abdominal surgery.