Endoscopy ; methods ; Epidermal Cyst ; surgery ; Female ; Humans ; Middle Aged ; Skull Base ; pathology

Autoimmune Diseases ; Humans ; Laryngeal Diseases ; Sarcoidosis ; Vocal Cords ; pathology

Objective To explore the effect of endoscopic sinus surgery on inverted papilloma of nasal cavity and paranasal sinuses in 30 cases.Methods 30 patients with inverted papilloma of nasal cavity and paranasal sinuses were operated on by endoscopic sinus surgery.Results During a follow-up of 2～3 years,only four cases recurred, Conclusion Endoscopic sinus surgery had advantsges of clear field and little injury,and therefore it was effective for inverted papilloma of nasal cavity and paranasal sinuses.

Adult ; Chronic Disease ; Female ; Humans ; Kidney Transplantation ; adverse effects ; Male ; Middle Aged ; Nasal Polyps ; etiology ; Postoperative Complications ; Sinusitis ; etiology

Child ; Humans ; Laryngeal Diseases ; pathology ; therapy ; Vocal Cords ; pathology

Acetylcholine ; pharmacology ; Adenocarcinoma ; metabolism ; Cell Line, Tumor ; Gastric Mucosa ; cytology ; drug effects ; metabolism ; Humans ; Receptors, Cholinergic ; metabolism ; Stomach Neoplasms ; metabolism

Acetylcholine ; pharmacology ; Cell Line, Tumor ; Cell Membrane ; Epithelial Cells ; cytology ; Gastric Mucosa ; cytology ; drug effects ; metabolism ; Humans ; Receptors, Nicotinic ; drug effects ; metabolism ; Stomach Neoplasms ; metabolism

Objective:This paper investigates the difference of chronic disease in different social class of the elderly in Beijing .Method: Date of a representative sample included 1717 residents aged 60 and above are drawn from Beijing elderly household survey 2013 conducted by Peking university school of public health .With income , ed-ucation , occupation and residence household as indicators of social class , logistic regression model is used for analy-zing the difference of chronic disease prevalence among different socio-economic status .Result:The non-agricultural household group , middle and highest income group , the least and highest groups of education have a lower probability and the farming , forestry, animal husbandry and fishing water production personnel before retired have a higher risk of suffering from chronic disease .In terms of multiple chronic diseases , second lowest 20%income group tie to high-er risk of suffering three or more chronic conditions simultaneously .Conclusion: Strategies development of chronic disease prevention and control should take full account of social determinants of health such as the social stratifica -tion , not just for the direct cause of chronic diseases .Agricultural household , low-income and low-education group of people should be priorities in Beijing elderly chronic disease prevention and control .

Cicatrix ; therapy ; Humans ; Laryngeal Diseases ; diagnosis ; therapy ; Vocal Cords ; pathology ; physiopathology

Objective: To investigate the effects of human tissue inhibitor of matelloproteinase 4 (TIMP 4) on vascular smooth muscle cells (VSMCs) migration and the neointimal formation after balloon injury in rats. Methods: The cultured VSMCs were transfected with an adenoviral vector containing human TIMP 4 gene, AdTIMP 4. Effect of TIMP 4 on VSMC migration was investigated by monolayer cell scrape. AdTIMP 4, control adenoviral vector or PBS was transduced into the rat carotid artery from the adventitial after carotid artery injury. Cell number within the internal elastic lamina 4 days after gene transfer was counted and neointima/media area ratio 28 days after gene transfer was calculated. Results: The migration distance of VSMCs infected with AdTIMP 4 was inhibited markedly. Morphometric analysis demonstrated a statistically significant reduction in the number of cells migrated into neointima compared with controls [(32.5?4.8) cells per section, (33.8?7.0) cells per section and (8.2?2.4) cells per section for uninfected, AdGFP treated and AdTIMP 4 treated arteries, respectively]. There was a reduction of intima/media ratio of TIMP 4 treated group by 66.5% compared with control groups 28 days after gene transfer ( P