1.Two cases report of autoimmune hemolytic anemia associated with acute kidney injury
Yunfang ZHANG ; Jian GUO ; Baojun HUA ; Jie LUO ; Hongyan LI
Clinical Medicine of China 2014;30(12):1259-1261
Objective To investigate the clinical characteristics of patients suffering from autoimmune hemolytic anemia(AIHA) associated with acute kidney injury (AKI).Methods The clinical data of 2 case patients with AIHA and AKI in the People's Hospital of Huadu District of Guangzhou was analyzed and associated literatures were reviewed.Results Two patients presented with severe anemia,raised reticulocyte count,positive Coomb's test,and acute renal failure.They were no effect therapy when treatment with agent of erythropoietin (EPO),iron or folic acid.The level of serum indirect bilirubin was at normal range.Liver function and serum LDH were normal too.However,treatment with corticosteroids was effective.Conclusion When patients suffering AKI occur worsening anemia,AIHA probably should be concerned.Treatment with corticosteroids early is effective.
2.Reproducibility of measurement of liver volume using multi-slice spiral CT
Jian SHU ; Jiannong ZHAO ; Dajing GUO ; Yindeng LUO
Journal of Third Military Medical University 2003;0(11):-
Objective To evaluate the reproducibility and agreement in the measurement of liver volume with multi-slice spiral computed tomography(CT).Methods Spiral CT was performed in 20 cases(14 healthy volunteers and 6 patients with cirrhosis).Images were transferred to a workstation,and volumes were measured by three observers with 5-year abdominal CT experience.Each observer performed the measurements in all subjects twice.Intra-observer and inter-observer variability was calculated using analysis of variance of the repeatedly measured results.The agreement was analyzed with the intra-class correlation coefficient(ICC).Reliability analysis in inter-observer was performed with Cronbach's alpha coefficient.Results Data measured by Observer A were(1 265.53?421.43)cm3 and(1 272.30?414.73)cm3 [difference:(0.80?2.20)%,P=0.15,ICC=0.998 8],Observer B(1 299.97?403.48)cm3 and(1 310.23?404.04)cm3 [difference:(0.90?1.90)%,P=0.07,ICC=0.998 3],Observer C(1 282.18?425.91)cm3 and(1 289.73?424.66)cm3 [difference:(0.70?2.60)%,P=0.19,ICC=0.998 3],respectively.The mean liver volumes by the three observers were(1 268.91?418.07)cm3,(1 305.10?403.59)cm3,and(1 285.97?425.10)cm3,respectively(P=0.07,ICC=0.986 9,Cronbach's alpha coefficient=0.995 6).Conclusion High reproducibility and agreement in the measurement of liver volume can be achieved with multi-slice spiral CT.
3.Disease characteristics of the patients in level-Ⅱ hospital for peacekeepers
Jian GUO ; Yonghe LUO ; Songjie FAN ; Jiandong ZHANG
Journal of Medical Postgraduates 2003;0(03):-
Objective:To summarize and analyze the disease characteristics of the patients in Chinese Level-II Hospital for UN Peacekeepers in Liberia,for offering some references to the pre-mission training of the successive contingents as well as the improvement of medical support to the peacekeeping mission.Methods:A statistical analysis was made of the case history of all the outpatients and inpatients received in Chinese Level-Ⅱ Hospital for UN Peacekeepers in Liberia from May 2004 to December 2005. Results:Out of the total of 7107 outpatients,2539(35.7%) were medical cases,1205(17.0%) surgical,1136(16.0%) dental,787(11.1%) dermatological and 763(10.7%) contagious cases.Malaria was the main type of contagious disease,which accounted for 86.1% of all the contagious cases.There were 39 cases of AIDS/HIV(acquired immunodeficiency syndrome / human immunodeficiency virus).Of the 453 inpatients,233(51.4%) were contagious and 166(36.7%) medical cases,and 185(40.8%) of the total number suffered from malaria.The average hospital stay was 5.2 days.Conclusion:Adequate drugs and equipments should be prepared for both common and special diseases in the peacekeeping mission area.During the pre-mission training at home,special emphasis should be laid on the prevention and treatment of common diseases and frequently occurring diseases,particularly on the diagnosis of and protection against AIDS.
4.Development of Portable Multi-function Heart-Sound Auscultating System
Qingfeng LIAO ; Xingming GUO ; Jian ZHANG ; Ke CHEN ; Jing LUO
Chinese Medical Equipment Journal 2004;0(09):-
Objective To overcome the disadvantages of the traditional auscultating method and design the electro-auscultating visual system integrating the monitoring and recording functions.Methods The portable system consisted of the module pre-gathering and electro-auscultating heart-sound signal,the circuit of A/D converting and MCU,as well as the device of signal LCD-displaying in real-time and the USB mass storage device.Results Portable electro-auscultating system was realized,which integrated the functions of watching,monitoring and recording.Conclusion The portable system is more convenient for clinical doctors to get correct information from patients,benefiting to the clinical pathology-statistics and profound development of the related data.
5.The value of prenatal ultrasonography in the diagnosis of congenital anal atresia
Jinqiang GUO ; Qianjiao LI ; Fuming WANG ; Jian LUO
Chinese Journal of Primary Medicine and Pharmacy 2016;23(17):2684-2686
Objective To evaluate the clinical value of prenatal ultrasound in the diagnosis of congenital anal atresia.Methods A retrospective analysis was studied from January 2013 to December 2015 which analyzed abnormal sonographic features by prenatal ultrasound screening in 13 cases of anal atresia.Results 13 cases of anal atresia were confirmed after abortion,miscarriage or birth which were not probed target ring signby prenatal ultrasound screening.That included 2 simple atresia cases and 11 cases associated with other malformations and abnormalities including 8 cases with bowel dilatation and 3 cases with intestine visible echogenic meconium. Conclusion Prenatal ultrasound screening for fetal congenital anal atresia can be detected.But for lacking of specific diagnostic standard,the detection rate of anal atresia remains very low.
6.CT findings of adrenal gland trauma
Maozhu WU ; Wenbin JI ; Qi YING ; Weidong CAI ; Yong GUO ; Jian ZHOU ; Wangqi LUO ; Nianjia ZHAO
Chinese Journal of Radiology 2008;(3):302-305
Objective To stuay CT findings of adrenal gland trauma(AGT).Methods The CT images of adrenal gland trauma which were found in 1712 patients who had emergency abdominal CT examinations for assessment of blunt force trauma were analyzed restrospectively.Results Among 1712 cases.we identified 29 patients(1.7%)with adrenal gland traumatic lesions.A total of 32 lesions were found.Twenty-six lesions were unilateral(23 right-sided,3 left-sided),and 3 cases were bilateral(6 lesions).Main CT findings were as followed:(1)Adrenal hematomas appeared as discrete round or oval masses expanding the adrenal gland in 22 patients with 25 lesions.The lesions were hyperdense or of homogeneous density in plain scan and did not enhance in three-phase contrast-enhanced dynamic scan.The splayed adrenal limbs around hematoma were enhanced significantly as eurvilinear structures.(2)Mild to moderate uniform swelling of gland was shown in 4 cases.(3)Diffuse irregular hemorrhage obliterating the gland was shown in 3 cases.Contrast extravasation was shown in 1 case,which was active bleeding from the broken adrenal gland proven by operation.Associated CT findings included strand-like hemorrhage of the periadrenal fat and posterior pararenal hemorrhage mimicking thickened diaphragmatic crus.The concurrent injuries of ipsilateral thorax or/and abdomen were found in 25 patients.Conclusion The AGT has typical CT findings.Familiarity with characteristic CT findings of adrenal trauma is essential for the radiologist to avoid misdiagnosis.
7.Cosmetic effects of oncoplastic volume displacement technique in breast-conserving surgery
Jian LUO ; Xiaodong ZHENG ; Li GUO ; Mingshe XIE ; Xia YU ; Xi FU
Chinese Journal of Medical Aesthetics and Cosmetology 2010;16(4):230-232
Objective To explore the cosmetic effect of oncoplastic volume displacement in breastconserving surgery.Methods 43 cases of breast cancer in stages I and Ⅱ with pathological diagnosis by core needle biopsy were operated by extended resection of tumor combined with axillary lymph nodes dissection.Among the patients,wound cavity was repaired by direct skin suture without suture of mammary gland deletion in 22 cases,and another 21 cases were repaired by oncoplastic volume displacement technique in which skin suture followed by freeing remaining breast tissue flap and translocation to repair the mammary defect.All of them were treated with three-dimension conformal radiotherapy,standard chemotherapy and endocrine therapy after operation.3 years after partial removal of breast,a retrospective historical control study had been fulfilled to analyze breast cosmetic results between two groups.Results In direct suture group,the cosmetology score was 4.3 points and fine rate was 40.9% (9/22).In breast reconstruction group.the score was 4.8 points and fine rate was 71.4% (15/21).The breast cosmetic effect in breast reconstruction group was significantly better than that in direct suture group (P<0.01).Conclusion It will get better breast cosmetic results after operation to utilize oncoplastic volume displacement suture technique in breast-conserving surgery.
8.The difference and correlation of the expression of hypoxia reaction genes at different time of kainic acidinduced epilepsy in rats
Tingxian NIU ; Xiaoming FENG ; Xiaohong LUO ; Xiaoyu GUO ; Lu LU ; Hongyi WANG ; Jian SHEN
Chinese Journal of Behavioral Medicine and Brain Science 2015;24(7):580-583
Objective To investigate the difference of the expression of hypoxia reaction genes of vascular endothelial growth factor(VEGF),erythropoietin (EPO) and hypoxia-inducible factor-1 alpha (HIF-1α)) at different times of rats that were induced epilepsy by kainic acid (KA),and analyze their correlation.Methods The epileptic rat model was established by intraperitoneal injection of kanic acid.The expression of VEGF,EPO and HIF-1α gene were detected by real-time fluorescent quantitative PCR assay with TaqMan probe in different times after intraperitoneal injection of KA.Results Compared with normal sodium (NS) group,the expression VEGF was higher at 12 h((8.38±1.27) ×10-3 ng/μl,P<0.05)) and 24 h((8.30±5.08) ×10-3 ng/μl,P<0.05)),EPO was higher at 12 h((8.42±0.90) × 10-5 ng/μl,P<0.05)) and 48 h ((1.50±3.25) × 10-2 ng/μl,P<0.01)) while the HIF-1α was higher at 24 h((2.11±0.21) × 10-2 ng/μl,P<0.01)),48 h((1.50±0.33) × 10-2 ng/μl,P<0.05))and 72 h((1.64±0.16) × 10-2 ng/μl,P<0.01)).Furthermore,the expression of EPO showed significant correlations with HIF-1α and VEGF (r=0.573,0.471,P<0.05),VEGF and HIF-1α had eminent correlations (r=0.803,P<0.01).Conclusions The expression of VEGF,EPO and HIF-1α participate in the seizure procedure and there is certain correlation between the three genes.
9.The follow-up value of D/S ratio in CHF patients with treatment
Kangla LIAO ; Jian QIN ; Hui LIAO ; Suxin LUO ; Xingming GUO ; Shouzhong XIAO
Chongqing Medicine 2015;(27):3779-3781
Objective To explore the follow-up value of phonocardiogram D/S ratio in CHF patients with treatment.Methods Forty-eight CHF patients who had never under-went regular treatment were collected in our hospital,given the regular anti-heart failure treatment for 3 months.NYHA heart failure classification,resting heart rate(RHR),and D/S ratio of phonocardiogram were recorded,six-minutes walk distance(6MWD),Left ventricular end diastolic diameter(LVEDd),the left ventricular ejection(LVEF) were tested before and after treatment.After 3-month treatment,the resting heart rate 65 times as the watershed,the patients were classified into two groups:one was up to standard,and the other was not up to standard.D/S ratio,RHR,6MWD,LVEDD,LVEF and the improvement of the heart function were compared between the two group.Results Exception the resting heart rate,the in-dicators had no significant improvement in the group of not up to standard compared with the before treatment,and D/S ratio, 6MWD,LVEF was improved significantly after three months treatment(P <0.05).In the group of up to standard,the D/S ratio was improved significantly after one months treatment(P <0.05),while after three months treatment all indicators were improved significantly(P <0.05).Comparison between the two groups,the RHR,D/S ratio were significantly improved(P <0.05 ),LVEF was significantly improved after three months treatment(P <0.05).At the same time,the D/S ratio,6MWD and NYHA classifica-tion of cardiac function was significant negatively correlated(P <0.05).Conclusion The D/S ratio could reflect heart functional im-provements in patients with CHF after anti-heart failure treatment,and it could reflect the heart functional improvement earlier and more significant in the group up to standard,it has a good clinic follow-up value in CHF patients with anti-heart failure treatment.
10.Analysis of iodized salt monitoring results in Chongqing Municipality from 2001 to 2009
Bang-zhong, XIAO ; Jing, CHEN ; Cheng-guo, WU ; Ya-lin, CHEN ; Xing-jian, LUO
Chinese Journal of Endemiology 2011;30(4):416-419
Objective To monitor the quality changes of iodized salt and analyze its impact factor in Chongqing between 2001 and 2009. Methods Salt samples were collected according to the east, west, south,north and center locations in iodized salt production, wholesale and household sectors. Two units in iodized salt production and wholesale segment were sampled from north, south, east and west places and only 1 unit was sampled from the central place. Nine samples were collected every month in each place. If the place had less than 9 units, and then taken all the units. About resident household, 2 townships were sampled from north, south, east and west places, and 1 township was sampled from the central place, then 20 samples were collected from each township. Iodine content was detected by oxidation-reduction assay. The index of mean iodine, qualified rate from factories and wholesale, coverage rate and taking rate of qualified iodized salt in residents were calculated.Significance was analyzed by trend test, analysis of variance and X2 test. Results The qualified rate of iodized salt from the manufacturers was 92.9%(13/14) in 2001 and the rate was 100.0% each year from 2002 to 2009. The qualified rates of iodized salt from the wholesale were 88.7%(282/318) - 99.8%(431/432). The rates of 2001 and 2002 were lower than that of other years(X2 = 4.98 - 45.69, all P< 0.05 or < 0.01). The coverage rate and taking rate of qualified iodized salt in residents were 94.2% (11 154/11 841 ) - 98.9% ( 14 061/14 217), 83.5% (9 887/11 841 ) -95.8% (13 449/14 039), respectively. The rates showed an increasing tendency (F = 9.27, 26.39, all P < 0.05).The districts(counties) with qualified iodized salt consumption rate > 90% kept increasing. The mean iodine from the manufacturers and wholesale were 29.71 - 36.25, and 31.26 - 36.13 mg/kg, respectively. The iodine level showed a descending trend(F = 35.45, 140.59, all P < 0.01 ). The mean iodine level from the inhabitants were 28.84 - 30.98 mg/kg which remained stable (F = 3.05, P > 0.05 ). The iodine level from manufacturers, wholesale to inhabitants showed an descending trend(F = 38.46 - 671.23, all P < 0.01 ). Conclusions The surveillance results of iodized salt shows an increasing tendency in quality of iodized salt, eoverage rate and taking rate of qualified iodized salt. Factors that affect the quality of iodized salt is that the enterprise does not add iodine to salt strictly by the standard.

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