1.Molecular genetics of atrioventricular septal defects.
Chinese Journal of Pediatrics 2005;43(5):390-392
3.Expression of hyaluronan in laryngeal carcinoma.
Zhao HAN ; Guo-jing LIN ; Jian-min HUANG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2005;40(11):867-868
Adult
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Aged
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Carcinoma, Squamous Cell
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metabolism
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pathology
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Female
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Humans
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Hyaluronic Acid
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metabolism
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Laryngeal Neoplasms
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metabolism
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pathology
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Male
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Middle Aged
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Neoplasm Staging
4.Acute toluene or xylene poisoning case analysis of domestic journals.
Jian-shu HUANG ; Yuan-ling ZHOU ; Wei-guo WAN
Chinese Journal of Industrial Hygiene and Occupational Diseases 2013;31(5):369-371
Acute Disease
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Adolescent
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Adult
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Aged
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Female
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Humans
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Male
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Middle Aged
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Toluene
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poisoning
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Xylenes
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poisoning
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Young Adult
6.Multi-segment transpedicle spinal fixation for thoracolumbar fractures with ankylosing spondylitis:one-year follow-up
Xingguo WU ; Jian HUANG ; Yuqing JIANG ; Weikang GUO ; Jun WANG
Chinese Journal of Tissue Engineering Research 2014;(9):1368-1373
BACKGROUND:Because of osteoporosis, short-segment transpedicular fixation or screw-rod system fixation is prone to screw loosening depending on its poor anti-pul-out strength in patients with thoracolumbar fracture with ankylosing spondylitis.
OBJECTIVE:To probe the clinic outcomes of multi-segment transpedicle spinal fixation for thoracolumbar fractures with ankylosing spondylitis.
METHODS:Eleven patients with ankylosing spondylitis combined with thoracolumbar fracture in the Fourth Department of Orthopedics, Meizhou Hospital, Sun Yat-sen University, China from January 2009 to December 2012 were selected. Al the patients underwent posterior reduction and multi-segment transpedicle spinal fixation, among whom, six cases were subjected to internal fixation through the pedicle of fractured vertebra.
RESULTS AND CONCLUSION:Al of the 11 patients were fol owed up for 13 to 36 months. Solid bone healing was achieved in al of the patients, and there were no complications related to the internal fixation systems such as loosening or breakage. Three cases of spinal cord injury achieved Frankel’s class E from class C recovery. Lumbodorsal pain rate achieved 100%according to the Japanese Orthopaedic Association scoring. Results confirmed that it is effective to treat thoracolumbar fractures with ankylosing spondylitis by posterior reduction and multi-segment transpedicle spinal fixation. Strong internal fixation and fracture union can be achieved by operation.
7.Insight and inquiry for the corporate governance reform of public hospitals in Weifang
Jin HUANG ; Hongcai ZHANG ; Xiaogang GUO ; Jian HAN
Chinese Journal of Hospital Administration 2011;27(12):893-895
An introduction to general guidelines and practices of reforming the corporate governance of public hospitals in Weifang,Shandong province.Such guidelines and practices include the following:set up a government hospital administration,and clarify the rights and responsibilities of public hospital owners; clarify the independent status of legal person of the hospital to revitalize it; improve the check and balance mechanism to ensure its effectiveness and order.Such a reform has streamlined the management framework of public hospitals,and mobilized incentives of both the director and the staff,further enhancing the public benefit characteristics of the hospitals and satisfying the patients.
8.The diagnostic value of musculoskeletal ultrasound in gouty arthritis
Yan ZHANG ; Hong ZHANG ; Junhua GUO ; Jian ZHU ; Feng HUANG
Chinese Journal of Internal Medicine 2012;51(4):304-307
Objective To observe the characteristic features of musculoskeletal ultrasound (MSUS) in gouty arthritis (GA) and to assess its value in GA diagnosis.Methods Patients with GA and non-GA who underwent MSUS examination in Chinese PLA General Hospital were enrolled in this study. The synovitis,tenosynovitis,soft tissue swelling,bone erosion,bursitis and ossification were measured by greyscale ultrasound,and the synovial vascularity was measured by power Doppler ultrasound to evaluate the degree of inflammation.Results The ultrasound images of GA were intended to have specific features like tophus,hyperechoic deposition on the surface of the articular hyaline cartilage ( double contour sign ),hyperechoic deposition in the synovium appearing as bright stippled foci,and bright strap in tendons with a significant difference when compared with non-GA group (P < 0.05).The percentage of tenosynovitis and bone erosion in non-GA group was higher than that in the GA group with a significant difference (P <0.05 ). Tophus,double contour sign,bright stippled foci or bright stippled foci in tendons together suggested gout with a specificity of 92.4% and a sensitivity of 60.3%,the AUC of ROC was 0.764 ( P <0.05).Conclusion Tophus,double contour sign,bright foci and bright strap detected by MSUS are of diagnostic value on GA and MSUS may be a promising tool in diagnosing GA.
9.Cyclodextrin and Its Derivatives as Non-viral Gene Vectors
Xiao ZHANG ; Zhi-Zhang GUO ; Lan HUANG ; Jian-Shu LI ;
China Biotechnology 2006;0(10):-
Cyclodextrin(CD) is gradually applied in the nonviral gene vector system,due to its biocompatibility and flexibility of tailing via structural modification,polymerization or supramolecular combination.The ideas and research progress of the CD,its low molecular derivatives,CD polymers and CD supramolecular combination in the field of norviral gene vectros were reviewed,and their "structure-safety-transfection efficiency" relationships were discussed.
10.Clinical and genetic features of Barth syndrome in three patients
Lin SHI ; Lijun FU ; Meirong HUANG ; Ying GUO ; Jian WANG
Journal of Clinical Pediatrics 2015;(7):614-617
ObjectiveTo explore the clinical presentation, diagnosis, treatment, and outcome of the Barth syndrome (BTHS).MethodsClinical data were collected and analyzed from 3 patients with conifrmed genetic diagnosis of BTHS from June 2013 to October 2014.ResultsAll of the 3 patients were males and two of them were twins. The main clinical manifes-tations of the 3 patients were cardiomyopathy and heart failure, accompanied by different degrees of trabeculations of the left ventricle. Two of them were diagnosed of left ventricular noncompaction (LVNC). All of the 3 patients presented with motor retardation, muscle weakness, growth delay and signiifcantly increased urinary excretion of 3-methylglutaconic acid (3-MGC). One patient was found to have neutropenia. All 3 patients hadTAZ gene mutations which included a novel missense mutation (c.527A>G, p.H176R) detected in the twins and a known nonsense mutation (c.367C>T, p.R123X) identiifed in the other patient. All of the mutations were inherited from their mothers. During the follow-up, the twins died at 7 months old and 7.5 months old respectively. The other patient was still alive.ConclusionBTHS is one of the causes of cardiomyopathy in children. In the male patients who presented with muscle weakness, neutropenia, and increased urinary excretion of 3-MGC, especially in those com-bined with LVNC, BTHS should be screened.