1.Appealing for Freer Academic Atmosphere in Bioethics
Zhaojiang GUO ; Changyong MA ; Xiao MA ; Song LI ; Jian HUANG
Chinese Medical Ethics 1994;0(05):-
Bioethics, one of the focus subjects in 21 century,attracts the attention in the worldwide.Originated from western developed countries,it has been branded with distinct western civilization,which is disadvantageous to the development of the subject.Some suggestions are put forward as following: 1.Communication between the East and the West should be promoted in order to form a solid multi-cultural base for bioethics. For instance, in America ethics bears the imprint of religious conventionality,while in China politics is infiltrated into traditional ethical ideas. Both of them are not perfect. So they cannot form the base of bioethics. 2.Research on the "base line" of the bioethics should be emphasized in order to provide freer academic atmosphere. Transplanting the western bioethical ideas to the developing countries will never work. As for the bioethical"base line",different countries should establish feasible ethical codes according to their own actual situations. 3.Scientists should be encouraged to adopt various technical ways to explore the problems in the field of bioethics.Such methods as tissue-engineering,antologous stem-cell replanting and cell diffrenttation inducing may bring about earlier breakthrough than fetus stem-cell.Equal attention,encouragement and support should be given to bioethics.
2.Relationship between Change of Cerebral Hemodynamic and Brain Injury in Neonates
xiao-li, MA ; jin-zhi, SONG ; jian-ming, LI
Journal of Applied Clinical Pediatrics 2004;0(08):-
The cerebral blood flow of infant is effected by physiological and pathological factors.As the cerebrovascular autoregulation of neonates is poor,in pathological cases,especially when hypoxemia and hypercapnia impaired regulation of its own,lead to changes in cerebral blood flow,then resulting in severe brain injury.It has made enormous progress in the research on the changes of cerebral blood flow in newborns in recent years.In normal infants,cerebral blood flow velocities is positively correlated to gestational age and body weight,and increase gradually with day-age in the first week after birth.The cerebral blood flow of newborn with brain injury can present as insufficiency,over-perfusion or low speed high-resistance earlier and high speed low-resistance later.Different results may be related to the duration and severity of asphyxia,but all of those are signs of damage of self-regulatory function of cerebral blood flow.Cerebral hemodynamic change is the important pathogenesis mechanism of brain injury.
3.Myocardial ischemia analysis based on electrocardiogram QRS complex in time domain
Jinzhong SONG ; Hong YAN ; Xiao-dong ZHANG ; Jian JIANG ;
International Journal of Biomedical Engineering 2011;34(3):163-166
Objective ST-T complex change, which represents the ventricle repolarization phase, is the main clinical indicator in detecting myocardial ischemia (MI) based on electrocardiogram (ECG) signals.However, its feature point location is not accurate due to interferences. In this paper, a new approach about myocardial ischemia analysis was proposed based on QRS complex. Methods QRS complex, representing the ventricle depolarization process, was used to analyze myocardial ischemia, and some parameters were extracted synthetically in time domain. Then they were used for statistical analysis of myocardial ischemia states and non-myocardial ischemia states. Results Five parameters had significant differences after verification of Non-MI signals in MIT-BIH database and MI signals in long-term ST database (LTST) and they were: QRS upward and downward slopes, transient heart rate, R angle and Q angle in a triangle QRS. Conclusion Five parameters extracted from QRS complex had significant differences. The proposed method provides an important basis for myocardial ischemia detection.
4.The follow-up observation of an impacted molar adjacent to implant:A case report
Jiang SHANG ; Jian SONG ; Sheng XU ; Huijuan XIAO ; Zhonghao LIU
Journal of Practical Stomatology 2016;32(1):137-139
A patient was treated by multiple dental implants,the implanted 6 was adjucent to impacted 8 .Immediately after implanta-tion,4 month and 3 year after implantation the distace between 8 and 6 implant central line was 4.4,3.2 and 2.5 mm,the angle between 8 long axis and 6 implant central line was 42.3°,45.5°and 50.3°.Then 8 was extracted.
5.Effect of PDTC on MCP-1 in rejection of cardiac allograft
Xiao BAI ; Jian ZHANG ; Guangmin SONG ; Xin ZHAO ; Wei WANG
Chinese Journal of Thoracic and Cardiovascular Surgery 2014;30(5):304-306,308
Objective To investigate the effect of pyrrolidine dithiocarbamate(PDTC) on monocyte chemotactic protein1 (MCP-1) in rejection of cardiac allograft and its mechanisms.Methods Heterotopic cervical heart transplantation was performed by cuff-technique.The SD rat recipients were randomly divided into 3 groups:AR group (Acute rejection,n =12),both the recipients and donors were without any treatment.CsA group(n =12),the recipients were treated with 10 mg/kg cyclosporine A after transplantation.PDTC group(n =12),the recipients were treated with 100 mg/kg PDTC after transplantation.All the cardiac allografts were harvested at different time post transplantation according to requirements.We studied allograft myocardial fibrosis wih the help of Masson stain,immuno-histo-chemistry and western blot also were used to detect the expression of MCP-1.Results The survival time of the cardiac allografts was significantly longer in PDTC group than in acute rejection group and CsA group(P < 0.01),and myocardial fibrosis of cardiac allografts in PDTC group was significantly decreased (P < 0.01).The IOD in PDTC group was markedly lower than in CsA group (P < 0.01).Conclusion As the inhibitor of NF-κB,PDTC can significantly relieve rejection of cardiac allograft by inhibiting the expression of MCp-1.
6.Analysis on blood supportability of Chengdu blood station of PLA after Wenchuan earthquake
Guobiao ZHU ; Jie XIAO ; Tao PENG ; Xinyu GAN ; Jian SONG
Chinese Journal of Trauma 2009;25(4):372-375
Objective To statistically analyze data of blood transfusion from General Hospital of Chengdu Military Command,Mianyang field blood station,Deyang field blood station and other military medical institutions from May 12 to June 30,2008 so as to provided certain references for reasonable blood supportability in wartime and disaster.Methods A statistical analysis was done on data of blood collection and supply including self-taken blood and assembled blood,total amount of blood supply as well as the transfusion information of inpatients injured by earthquake in our hospital.Results The amount of self-taken blood was 5 111 U,the amount of assembled blood 3 380 U and the total amount of blood supply 1 0405.5 U.But blood transfusion was 4 090.6 U in 132 patients admitted into General Hospital of Chengdu Military Command.In addition,the crest-time of transfusion appeared at 96 hours after earthquake.Moreover,patients with fractures received the highest rate of blood transfusion and crush syndrome patients received the most blood transfusion and the highest per capita transfusion.Conclusions Blood supportability in earthquake is different from that in wartime and other disasters in aspects of transfusion time,blood types and blood transfusion volume.It is important to analyze the characteristics of transfusion in patients injured by earthquake for national strategy of blood supportability in disasters and for blood supportability in the wartime.
7.An analysis on the urinary thiocyanate of 149 health crowd in Nanjing.
Xiao-lian QIAN ; Hai-yan SONG ; Jian-ling BAI
Chinese Journal of Industrial Hygiene and Occupational Diseases 2012;30(8):595-596
Adult
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Female
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Food Industry
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manpower
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Humans
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Male
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Middle Aged
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Smoking
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epidemiology
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Thiocyanates
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urine
8.Studies on anti-inflammatory effects of Zengxuean Capsule
Jian LIU ; Jie SONG ; Zhenxiu LIU ; Peigen XIAO ;
Chinese Traditional Patent Medicine 1992;0(01):-
Objective: To study the pharmacological effects of Zengxuean capsule (Radix Astragali, Indigo Naturalis, Cordyceps, etc) on anti inflammation.Methods:A few conventional models, such as the mouse pinna swelling induced by croton oil, were employed to determine the anti inflammatory activities of Zengxuean capsule.Results: Zengxuean capsule obviously inhibited the swelling of mouse pinna induced by croton oil, suppressed the edema of rat hind paw elicited by injection of 1% carrageenan, significantly depressed the increase of peritoneal capillary permeability in the xylene induced mice, and greatly decreased proliferation of granuloma led by implanting cotton pellet. It had an abatement effect of algesia induced by heat with tail flick method, and could not inhibit the swelling of pinna led by croton oil when mouse's adrenal was resected.Conclusion: Zengxuean capsule is an effective medicine on anti inflammation, and its acitivity is realized by adrenal cortical system.
9.Therapeutic effects of flunarizine combined with aspirin on patients with migrainous cerebral infaction
Weizhong XIAO ; Wei SUI ; Xinyu ZHANG ; Jian LI ; Hongsong SONG ;
Chinese Journal of Clinical Pharmacology and Therapeutics 2002;0(05):-
AIM: To explore the therapeutic effects of flunarizine combined with aspirin in the treatment of migrainous cerebral infaction. METHODS: 38 cases of patients diagnosed as migrainous cerebral infaction were respectively given flunarizine 10 mg combined with aspirin 100 mg every night for a month. The observed indices included the dysfunction scores of nervous system, the total classes of living ability, and the accumulating rate of platelet and viscosity of plasma before and after the treatment. RESULTS: Before the treatment the dysfunction scores of nervous system and the living ability of the patients were 13.51 ? 4.78 and 3.45 ? 1.13 , and after the treatment the values were 4.34 ? 1.85 and 1.79 ? 0.72 respectively (P
10.Mask lift and facial aesthetic sculpturing.
Xiao-ping CHEN ; Jian-liang SONG ; Song-min SHI ; Xiao-yan TAN ; Hao SUN ; Jin-de LIN ; Zhen-kun SONG ; Jian SHEN
Chinese Journal of Plastic Surgery 2004;20(6):405-407
OBJECTIVETo improve the outcome of the face-lift with a craniofacial contouring procedure.
METHODSThirty-seven patients aged 29-53 years (31 in female, 6 in male) were treated through a bicoronal incision. The facial tissue was lifted through a subperiosteal procedure and the facial skeleton was remodeled in three dimensions by osteotomies.
RESULTSThe results were satisfactory after the 3-12 months of the follow-ups.
CONCLUSIONSThe Face-lift combined with the facial aesthetic sculpturing may be more effective for the aging-face rejuvenating.
Adult ; Esthetics ; Female ; Humans ; Male ; Middle Aged ; Rhytidoplasty ; methods