BACKGROUND:Traditional Chinese medicine glossoscopy observes tongue image by vision,and to diagnose diseases by physicians'clinical experiences,which lacks of objective diagnostic methods and criteria;finally resulting in affecting the effectiveness of this diagnostic method.Therefore,it is necessary to realize quantitive and objective glossoscopy using techniques such as computer vision.Tongue body segmentation is the premise of the tongue image recognition diagnostic system.The quality of segmentation directly affects the sequent work.At present,there are many methods of tongue body segmentation,but obtained results cannot ensure the accuracy,and the anti-interference ability is poor.OBJECTIVE:To design a new method of tongue image segmentation,and effectively isolate tongue body.METHODS:According to tongue-images gray and color's features,a segmentation method of combining gray projection and threshold-adaptive way is presented in this paper.By this method,the intensity image of a colorful tongue-image is firstly projected at horizontal and vertical direction to locate the tongue-body area,and then threshold-adaptive way Otsu is used to segment the located area.RESULTS AND CONCLUSION:Tongue-body segmentation is the basis of automatic tongue-images analysis.The following 281 tongue-images segmentation experiments show the efficiency of this method.

Acupuncture Points ; Aged ; Aged, 80 and over ; Bloodletting ; Female ; Humans ; Middle Aged ; Pruritus ; therapy

Child ; Diabetes Mellitus, Type 1 ; genetics ; Female ; Humans ; Infant ; Male ; Siblings

ObjectiveTo observe the e ff ect of NO precursor or/and NOS inhibitor on the survival of acute liver failure( ALF) rats.MethodsModel of ALF rat was established by resecting 90% of the rat liver and the effect of NO prec ursor or/and NOS inhibitor was observed.Resu ltsAdministration of NO precursor significantly improved the liver, lung, kidney and bowel function. The rats′ survival rate at 24 h, and 72 h increased significantly, whereas NOS inhibitor deteriorated fu nctions of important organs(P

[Objective]To observe the clinical treatment of calcaneus fracture with poking reduction and artificial bone grafting technique.[Method]From 1999.6 to 2005.5,60 cases with recent calcaneus fracture,including 46 feet in 38 males and 24 feet in 22 females with falling injure;aged from 20 to 65,were equally divided into two groups,including the observed group treated with poking reduction and artificial bone grafting and the control group with steel needle pry-poking reposition.[Result]During followed up for 6-60 months,average 20.7months,it was notable different in Maryland foot score,and the same in Bhler′,Gissane′ and Perie′ angle in X-ray in post-operation and pre-operative between observed group and the control.[Conclusion]It showed us that the technique of poking reduction and artificial bone grafting was liable to operate and could provide exactly efficiency.

Objective To investigate the correlation between 8 single nucleotide polymorphisms(SNPs) of FOXO3A gene and human longevity in Bama county.Methods Genotyping of FOXO3A gene was performed by TaqMan-PCR technique for 177 longevous peolpe(aged 90-110) from Bama longevity area and 148 healthy controls(aged 48-89) from Bama non-longevity area.Results Minor allele frequencies of 5 known FOXO3A SNPs(rs2764264,rs9400239,rs13217795,rs2802288 and rs2802292)in cases were significantly higher than those in controls(P5%).Frequency of haplotype 'AG'in cases was significantly higher than that in controls,and frequency of haplotype 'TTTGTC'in cases was significantly lower than that in controls(P

OBJECTIVE:To analyze the utilization of drugs in children with ventricular septal defect(VSD) undergoing operation.METHODS:The medical orders of 120 VSD children patients in our hospital in 2005 were analyzed retrospectively.RESULTS:The per capita drug cost was(3 067.20? 325.04) yuan,accounting for 9.52% of the total medical cost.Circulatory system drugs and antibiotics were the chief categories.Leading the first 3 places in terms of DDDs were cefuroxime,vecuronium bromide and furosemide,respectively.CONCUSION:The drug cost for VSD children patients was relatively low and reasonable.

In recent years,with the increasement of intracranial pressure detection accuracy,the use of intracranial pressure detection in clinic become more common.Various of technologies are used in clinic that can be divided into invasive methods,such as epidural catheter,subarachnoid bolt,intraventricular catheter,fiberoptic catheter and micro-sensors transducer,and non-invasive methods,such as evoked otoacoustic emissions,transocular method,transcranial doppler,imaging method and magnetic induction method.This paper reviews the physiological basis of intracranial pressure detection and common intracranial pressure detection techniques,especially on noninvasive intracranial pressure detection methods.Advantages and disadvantages of different intracranial pressure detection methods are listed,and an outlook of the development of non-invasive intracranial pressure detection technology are made.

AIM: To analyze the effect of preoperative intravitreal injection of Ranibizumab ( lVR ) in patients undergoing pars plana vitrectomy ( PPV ) for proliferative diabetic retinopathy ( PDR) .
●METHODS:ln this retrospective research, 62 patients (67 eyes ) with PDR in the First Affiliated Hospital of Xinjiang Medical University from Jun. 2014 to Jun. 2015 were recruited. They were assigned to an experimental group ( n=37 eyes ) and a control group ( n=30 eyes ) . The patients in experimental group were given 1 injection of lVR ( Lucentis 1. 0mg/0. 1mL ) 1wk before surgery, whereas those in control group went down to surgery directly. The average operation time, iatrogenic breaks, the use of tamponade, electric coagulation, and vision increase rate were comparatively analyzed between two groups.
●RESULTS:The average operation time was (91. 7±20. 8) min in the experimental group vs (117. 6±18. 6)min in the PPV group(t = -5. 314,P<0. 05). The rate of electric coagulation (11%) vs (47%), (χ2 =8. 963, P=0. 006);iatrogenic breaks (5%) vs (33%), (χ2=8. 789, P=0. 004) and silicone oil or inert gas tamponade ( 27. 0%) vs (53. 3%), (χ2 = 4. 828, P = 0. 043 ). The rate of visual improvement (75. 7%) vs (46. 7%), (χ2 = 5. 960, P =0. 022 ) . There was no severe complication associated with surgery, such as choroidal detachment, retinal detachment and endophthalmitis.
●CONCLUSION:lVR before microincision vitrectomy can effectively shorten the operation time, reduce the use of electric coagulation and intraocular tamponade, and improve the rate of visual improvement for PDR patients.

Background To establish the ideal animal model of retinitis pigmentosa (RP) is very important for onward relevant study.Previous research determined that N-methyl-N-nitrosourea (MNU) can selectively damage photoreceptors via intravenous injection in mammal.However,whether MNU can be used to create an RP model needs to be investigated.Objective This experiment was designed to evaluate the toxic effect of MNU on photoreceptor cells of cats.Methods MNU was injected into 20 2-year-old cats via femoral vein and randomized into 20mg/kg, 25mg/kg, 30mg/kg, 35mg/kg and 40mg/kg MNU groups,and equal amount of normal saline solution was used in the same way in 4 normal cats as the control group.The activity,pupil size and light reflex were observed after injection of MNU.The cats were sacrificed and eyeballs were enucleated for histological examination to evaluate the structural and morphological changes of photoreceptors at 24 hours,72 hours,7 days and 14 days after the administration of MNU.This experimental study complied with the Statement for the Use of Animals in Ophthalmic and Vision Research.Results Dilated pupil and inertia of light reaction were found in experimental cats on the 7th days in the various groups.In 24 hours after MNU injection,the damage of photoreceptors was primarily characterized by pyknosis and disorder.In 72 hours after MNU injection,attenuation of the outer nuclear layer and disruption of cells were seen.Loss of photoreceptors and disappearance of the outer nuclear layer were observed on the 7th and 14th day.The extent of retinal photoreceptor cell damage was dependent on the dose of MNU.Conclusion MNU can selectively induce serious damage of the photoreceptor cells in cats retina in a time- and dose-dependent manner.