1.Analysis of the effects of mobile payment in outpatient service
Qiuqiao WANG ; Fengru LI ; Peina SHI ; Mei CUI ; Jian LIU
Chinese Journal of Hospital Administration 2016;32(4):288-291
Objective To learn the applications and patient experience of mobile payment technology as used in the hospital outpatient service.Methods 342 outpatients using mobile technology (APP)were chosen from the hospital information system for survey,and 300 outpatients registering in the conventional process were chosen as a control.Data of the doctor-seeing experiences of the two groups were analyzed statistically.Results Waiting queue reminder function is found with the highest patient usage among the three officially launched APPs,accounting for 83.6%.The appointment and cellphone payment functions exert the greatest impact on patient experience,boasting a patient satisfaction of 90%. All these functions can save totally one hour for an outpatient.Conclusions The mobile payment technology can significantly reduce outpatient waiting time,and improve outpatient experiences.Such technology therefore needs more promotions and connection with medical insurance system for the sake of outpatients.
2.1H-NMR based metabonomic approach to evaluate detoxification effect of vinegar-processed Euphorbia kansui.
Yu-Mei LIU ; Rong-Rong HUI ; Cui-Cui HE ; Jin-Ao DUAN ; Jian-Xin LI
China Journal of Chinese Materia Medica 2014;39(2):322-326
Euphorbia kansui (EK) is a toxic herbal drug, and often used after vinegar-processing to reduce its toxicity. In present study, a 1H-NMR based metabonomic approach was used to evaluate the detoxification effect of vinegar-processed EK. The water extracts of EK and VEK were administered orally to male SD rats at doses of 9 g x kg(-1) x d(-1) for 1 week, respectively, and one more week observation was further conducted. The control group was orally given with saline. Histopathological studies of liver samples on the 8th and 15th day were conducted, and the metabolites of rat urine and liver were analysed by 1H-NMR. Histopathological studies of liver samples from EK and VEK treated rats showed no negative impacts. In metabonomic analyses of urines, changes of metabolites indicated liver damages, kidney lesions and imbalance of gut microbes in the second week. VEK-treated rats showed a quite lower toxicity compared with EK-treated ones. The present study revealed that the metabonomic approach might be helpful for the evaluation of toxicity of EK and detoxic effect of VEK.
Acetic Acid
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chemistry
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Animals
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Chemistry, Pharmaceutical
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Drugs, Chinese Herbal
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chemistry
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pharmacokinetics
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toxicity
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Euphorbia
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chemistry
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Inactivation, Metabolic
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Liver
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drug effects
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metabolism
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Magnetic Resonance Spectroscopy
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Male
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Metabolomics
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methods
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Rats
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Rats, Sprague-Dawley
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Urinalysis
3.Exploration on the use of mobile Internet technology for hospital outpatient services optimization
Mei CUI ; Fengru LI ; Qiuqiao WANG ; Peina SHI ; Jie CHEN ; Qian LI ; Jian ZHANG
Chinese Journal of Hospital Administration 2014;30(12):902-904
Outpatient service constitutes a key part of hospital services.In an effort to optimize services plagued by the too long waiting time in registration,payment and drug dispensary,and the too short time in seeing doctors,Beijing Friendship Hospital introduced mobile Intemet technology into hospital outpatient services.Such measures as mobile payment,and realtime push of the information of patients waiting were adopted to help with outpatients waiting at home,minimize outpatients' movement,queuing and waiting.Simplified service process and higher service efficiency proved effective in winning higher outpatient satisfaction as a result.
4.Effects of iodine excess on TPO and NIS genes mRNA expression in rats
Jian-ying, XIA ; Jing-jing, SUN ; Xiu-mei, ZHANG ; Dan, YUE ; Cui-yao, WANG
Chinese Journal of Endemiology 2008;27(2):145-148
Objective To observe the effects of iodine excess on thyroid morphology,the expression of thyroid peroxidase and sodium iodide symporter mRNA and to explore their mechanisms.Methods One-month SD rats were divided into three groups:control iodine(CI),high iodine Ⅰ(HI Ⅰ)and high iodineⅡ(HI Ⅱ)and were fed with water containing iodine in different concentrations by adding K103(5,5000,10 000μg/L)respectively.Rats were sacrificed after being fed for six months.The morphology of thyroid was investigated under light microscopy and electron microscopy,the serum thyroid hormones and ratio of TPO/β-actin and NIS/β-actin were measured by radio-immunoassay and RT-PCR method.Results The major changes were increased follicles with colloid accumulation in HI groups.The levels of serum thyroid hormones TT3 and TT4 were decreased gradually from CI[(75.68±13.99,1.45±0.49)nmol/L]to HI Ⅰ[(73.82±16.48,1.34±0.31)nmol/L]and HIⅡ groups[(70.65±11.43,1.15±0.39)nmol/L],but there were no significant differences among three groups(F=O.371,l.163,P>0.05).The TPO and NIS mRNA expressions in HI Ⅰ(1.28±0.10,0.56±O.17)and HI Ⅱ(1.14±0.04,0.39±0.06)were significantly lower(F=30.863,62.62.675,P<O.05)than those of control group(1.39±0.08,0.71±0.13).Conclusions Chronic iodine excess leads to definite histological changes in rat thyroid,and inhibits the expressions of TPO and NIS mRNA as well as thyroid hormone synthesis,which in turn acts as a protective mechanism against iodine excess.
6. β-arrestins in regulating inflammatory diseases: Recent progress
Academic Journal of Second Military Medical University 2013;34(11):1237-1242
β-arrestins, important soluble proteins mediating receptor desensitization, have diverse biological functions, such as regulating cell proliferation, cell survival, apoptosis and gene transcription. β-arrestins regulate inflammatory and immune reactions by inhibiting the basal activity of pro-inflammatory transcription factor NF-kB and participating in Toll-like receptors (TLR)/NF-kB signal pathway-mediated NF-kB activation. β-arrestins are involved in the pathogenesis of various inflammatory diseases, such as inflammatory bowel disease, rheumatoid arthritis, ankylosing spondylitis, asthma and so on. The study on β-arrestins will reveal the mechanisms of inflammatory diseases and provide new strategy for clinical treatment. Here we reviewed the recent progress on the role of β-arrestins in regulating the inflammatory diseases.
7.Klinefelter syndrome complicated by mediastinal teratomas and precocious puberty: a case report.
Hong-hong ZHANG ; Ji-hua CUI ; Jian-qin QI ; Mei-rui LI ; Jian-min WU ; Yu LING
Chinese Journal of Pediatrics 2013;51(8):630-630
Biomarkers
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blood
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Child
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Chorionic Gonadotropin
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blood
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Follicle Stimulating Hormone
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blood
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Growth Disorders
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etiology
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Humans
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Klinefelter Syndrome
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complications
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diagnosis
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genetics
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Magnetic Resonance Imaging
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Male
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Mediastinal Neoplasms
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complications
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diagnosis
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surgery
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Puberty, Precocious
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diagnosis
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etiology
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Teratoma
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complications
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diagnosis
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surgery
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Testis
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pathology
8.Study of the thermal pain threshold latency of acupoints based on Fei Teng Ba Fa
Hong-Bin WANG ; Shu ZHAO ; Jian-Mei CUI ; Yan CAO ; Na SUN ; Jian-Shuai QI ; Yue-Yue YU ; Jue HONG
Journal of Acupuncture and Tuina Science 2018;16(3):140-144
Objective:By applying moxibustion to the eight confluent points in different periods of time,to observe the changes in thermal pain threshold latency of acupoints based on Fei Teng Ba Fa.Methods:A total of 468 healthy college student volunteers received moxibustion at the eight confluent points in three different periods of time,i.e.Chen (7:00-9:00),Wu (11:00-13:00) and Xu (19:00-21:00).The thermal pain threshold latency was adopted to measure the changes in pain threshold of the eight confluent points under different conditions (different periods of time,different genders,different acupoints and different states of the acupoints) based on Fei Teng Ba Fa.Results:Finally,thirty subjects dropped out and 438 subjects were included.The comparison of thermal pain threshold latencies of the eight confluent points in the same opening or closing state based on Fei Teng Ba Fa:latencies of the closing points and adjunct points were significantly different in different periods of time (P<0.05);the latencies of the males were significantly longer than those of the females (P<0.05);there was no significant difference in the latency between the left and right sides (P>0.05);in the female group,there was a significant difference in the latency between the lower-limb points and the upper-limb points (P<0.05).The comparison of thermal point threshold latencies of the eight confluent points in different opening or closing state:in the period of Wu (11:00-13:00),the latencies of the opening points were significantly longer than those of the closing points and adjunct points (P<0.05);for men,their opening and closing points had significantly longer thermal pain threshold latencies than their adjunct points (P<0.05);despite the gender,the latencies of the upper limb opening and closing points were significantly longer than the latency of the adjunct points (P<0.05);in the female group,the latencies of the lower-limb opening points were significantly shorter than those of the lower-limb closing and adjunct points (P<0.05).Conclusion:Based on Fei Teng Ba Fa,the pain thresholds of the eight confluent points vary in different periods of time,gender,acupoint location and opening/closing state,which can be taken as the evidence of making time-based acupuncture-moxibustion prescriptions.
9.Effects of active components in compatible solution of Sparganii Rhizoma-Curcumae Rhizoma on pelvic adhesion in rats with chronic pelvic inflammatory disease
Cui-Mei QIN ; Hong-Jian YU ; Jian-Mei CHEN ; Xiu-Lian CAO ; Yan-Qing REN ; Jiao LIU
Chinese Traditional Patent Medicine 2018;40(6):1233-1237
AIM To study the influence and action mechanism of effective components in compatible solution of Sparganii Rhizoma-Curcumae Rhizoma on pelvic adhesions of model rats with chronic pelvic inflammatory disease.METHODS Laboratory rats were randomly assigned into six groups,a sham-operated group,a model group,a positive Fukeqianjin tablets group,compatible solution groups (40 g/kg high-dose group,20 g/kg medi um-dose group,and 10 g/kg low-dose group).Except rats of the sham-operated group,those in the other groups were induced into models of chronic pelvic inflammatory disease by mechanical bacterial strain implantation,after which a 20 d corresponding drug administration by oral gavage for each group was initiated.After completion of the last drug administration,Verco criterion was taken as the reference to evaluate pelvic adhesions,HE staining was performed on uterine tissues for pathological scoring,ELASA method was applied to measuring serum IL-1β and TNF-α levels,and Western blot method was used to detect the expression levels of proteins FGF-2 and IGF-1 in uterine tissues.RESULTS Compared with the model group,the high-dose compatible solution group had a much sharper fall in Verco scores (P < 0.05),and remarkably decreased serum IL-1β and TNF-α levels (P < 0.01);both high-dose and medium-dose groups manifested with notably alleviated degenerative necrosis and lowered scores of chronic inflammation infiltration and epithelial hyperproliferation (P < 0.01 or P < 0.05),and a distinct reduction in the expression of proteins FGF-2 and IGF-1 (P < 0.05,P < 0.01).CONCLUSION The significant improvement of the chronic pelvic inflammatory disease in model rats due to the effective components in the compatibile solution of Sparganii Rhizoma-Curcumae Rhizoma may be associated with inhibited release of inflammatory mediators IL-1β and TNF-α,and the reduced expression of proteins FGF-2 and IGF-1 as well.
10.Histomorphological study on folk medicine Lysimachia fortunei.
Zhi-gui WU ; Xiao-mei FU ; Sheng-fu HU ; Jian-guo PEI ; Fei GE ; Xiao-lan CHU ; Cui-sheng FAN
China Journal of Chinese Materia Medica 2015;40(4):639-642
To set standards for histomorphological studies on Lysimachia fortunei, an efficacious and widely applied folk medicine in this study, in order to develop its resources. Its species were identified by observing plant morphology and herbs appearance characters, preparing slices with routine methods and defining structural characters. According to the results of morphologic observation, leaves, stamen and pistil of this plant were different from the descriptions in Flora of China. The whole herb can be used in medicines, mainly including rhizomes, stems and leaves. According to the findings in the first study on microscopic structures, its rhizomes, stems and leaves were characteristic and worth identifying. The transaction tissue structures of rhizomes and stems were under developed and contained endodermis, secretory structures; Stems had sclerenchymata of different shapes of sclereids; Leaves were bifacial and had vascular bundles under midribs, which were surrounded by parenchymal sheathes. On the surface of leaves, stomata, glandular hairs and keratin lines were morphologically different in upper and lower epidermis. The herbal power had glandular hairs, sclereids and vessels. In conclusion, herbs of L. fortunei can be identified by the above histomorphological characteristics, which lays a foundation for further development and application of L. fortunei.
Medicine, Traditional
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Plant Leaves
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anatomy & histology
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growth & development
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Plant Stems
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anatomy & histology
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growth & development
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Plants, Medicinal
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anatomy & histology
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growth & development
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Primulaceae
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anatomy & histology
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growth & development