2.Dispute and consensus about surgical approaches and lymph nodes excisional area of esophageal carcinoma.
Chinese Journal of Gastrointestinal Surgery 2011;14(9):667-670
Surgical approaches for esophageal carcinoma are many and varied. Minimally invasive techniques are increasingly used widely in esophagectomy as they not only ensure patients' therapeutic effects, but also reduce trauma and accelerate recovery. The lymph nodes excisional area of esophageal carcinoma is still in controversy. It is necessary to carry out further researches on selective lymph nodes excision, which can decrease complication rate and improve patients' survival in the meantime.
Esophageal Neoplasms
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surgery
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Esophagectomy
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methods
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Humans
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Lymph Node Excision
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methods
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Minimally Invasive Surgical Procedures
3.FTY720 reduces peritubular micrangium loss in renal interstitial fibrotic rats.
Chinese Journal of Pediatrics 2009;47(6):468-470
Animals
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Apoptosis
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drug effects
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Capillaries
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pathology
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Fibrosis
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Fingolimod Hydrochloride
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Kidney Diseases
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metabolism
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pathology
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Kidney Tubules
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blood supply
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Male
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Propylene Glycols
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pharmacology
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therapeutic use
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Rats
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Rats, Sprague-Dawley
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Sphingosine
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analogs & derivatives
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pharmacology
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therapeutic use
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Vascular Diseases
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prevention & control
4.Impact of Type 2 Diabetes on Manifestations and Radiological Images of Pulmonary Tuberculosis
Hong ZHU ; Juan XIE ; Jian-Hua WANG
Chinese Journal of Prevention and Control of Chronic Diseases 2006;0(06):-
Objective To explore the clinical features of pulmonary tuberculosis complicated with DM and related factors. Method The manifestations of 87 newly diagnosed PTB patients with type 2 DM(DM-PTB group) at two hospitals in Tianjin during October 2003 to October 2004 were compared to 88 PTB patients without DM who were randomly choosen from the same hosipital.The factors related to sputum-positive TB or cavity were explored through unconditional logistic regression model. Results DM-PTB patients showed significanly lower frequencies of cough(66.7% vs 83.0%),toxicity symptoms(37.9% vs 62.5%) and haemoptysis(16.1% vs 33.0%) than those of PTB group.Positive-sputum(63.2% vs 34.1%),cavity(56.3% vs 13.6%),wide lesions and bilateral lesions on chest radiographs was more common in DM-PTB group than in PTB one.Introversion(OR=1.582, 95%CI:1.063 ~2.355),type 2 DM(OR =2.186,95% CI:1.082 ~4.420)and cavity(OR =2.793,95% CI:1.308 ~5.964)were factors independently associated with positive-sputum TB.The factors related to cavity included diabetes(OR=14.199,95%CI:5.376~ 37.501),cough,postive sputum and lore-up lobe lesion.Conclusion This study confirmed that clinical manifestations and chest radiographs of PTB patients complicated with type 2 DM significantly departed from the typical presentation.Type 2 DM seems to have a negative effect on postive-sputum and cavity.So it should be alarmed that DM-PTB patients who tend to have untypical clinical symptom and higher rate of positive sputum become the reservoirs of infection to cause the transmission of TB.
5.Determination of soluble compounds of barium in the air of workplace by ICP-AES.
Gui-hua LIU ; Wei CHEN ; Jian-bin XIE ; Wei ZHAO
Chinese Journal of Industrial Hygiene and Occupational Diseases 2004;22(1):78-79
Air Pollution
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analysis
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Barium
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analysis
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chemistry
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Solubility
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Spectrophotometry, Atomic
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methods
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Workplace
6.Pyothorax-associated lymphoma: report of a case.
Li-hua WU ; Jian-lan XIE ; Xiao-ge ZHOU
Chinese Journal of Pathology 2009;38(3):205-206
Adult
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Antigens, CD20
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metabolism
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Empyema, Pleural
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complications
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diagnostic imaging
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pathology
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virology
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Epstein-Barr Virus Infections
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Humans
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Ki-67 Antigen
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metabolism
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Lymphoma, Large B-Cell, Diffuse
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metabolism
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pathology
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surgery
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virology
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Male
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Pleural Neoplasms
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complications
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metabolism
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pathology
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surgery
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virology
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Radiography
8.Oligonucleotide array of genomic expression in complete androgenic hydafidiform mole
Jianyun XU ; Feng YE ; Wei-Guo LV ; Die HONG ; Jian-Hua QIAN ; Xing XIE ;
Chinese Journal of Obstetrics and Gynecology 2001;0(08):-
Objective To compare genomic expression differences between androgenic complete hydatidiform mole (AnCHM) and normal first trimester villi with similar gestation weeks,and search for potential adjuvant diagnostic molecular markers.Methods Short tandem repeat (STR) detection was used to identify AnCHM,human oligonucleotide array U133 Plus 2.0 was used to measure genomic expression differences between AnCHM and normal villi,and quantitative fluorescent RT-PCR was used to verify array of several genes.Results Nine of 11 histologically diagnosed complete hydatidiform moles were found to be AnCHM by means of STR,and the other 2 were biparental complete hydatidifonn mole (BiCHM). Compared with villi,oligonueleotide array showed 279 genes (0.72%,279/38 500) were over expressed and 1710 genes (4.44%,1710/38 500) under expressed in AnCHM.Bioinformatics analysis found that differentially expressed genes were involved in multiple biological processes and pathways.Changes of imprinting genes,growth hormone genes and chorionie somatomammotropin hormone genes were especially remarkable.Conclusions Pathogenesis of AnCHM is a complex process involving multiple genes and pathways.Altered expression of imprint genes may play important roles in the process.
10.Preparation of albendazole sulfoxide--- an active metabolite
Journal of Zhejiang University. Medical sciences 2002;31(1):45-46
OBJECTIVE: To investigate the facile method for preparation of albendazole sulfoxide, an active metabolite in vivo. METHODS: The reaction condition was investigated according to evaluations to the results of the experiment through temperature, solvent, oxidation agent, reaction time and impurity. RESULTS: The target compound was obtained by oxidation of albendazole with the presence of sodium metaperiodate in glacial acetic acid under low temperature and was free from contamination by impurity albendazole sulfone. Pure product (content >98%) and high yield (>90%percnt;) have been achieved due to reaction selection. CONCLUSION: Oxidation condition is essential to the preparation of albendazole sulfoxide.