1.Clinical observation of phacoemulsification and IOL implantation for cataract patients with glaucoma
International Eye Science 2014;(6):1071-1073
AIM: To observe the efficiency of phacoemulsification with intraocular lens implantation in the treatment of cataract and glaucoma.
METHODS:Totally 60 patients ( 70 eyes ) with cataract and glaucoma were included between March 2010 and March 2012 in our hospital. The phacoemulsification with intraocular lens implantation was performed. The observation of surgical efficiency, including the patient's IOP, anterior chamber depth, vision and complications, were compared before and after surgery.
RESULTS:Compared with preoperation, the patients'vision and anterior chamber depth were increased and the IOP was reduced significantly (P<0. 05).
CONCLUSION: Phacoemulsification with IOL implantation is a safe and effective treatment for cataract and glaucoma.
2.Basic fibroblast growth factor and Alzheimer's disease
Daming ZHU ; An HONG ; Jian LIN
Chinese Journal of Pathophysiology 1989;0(05):-
Alzheimer's disease(AD),which is one type of senile deimentia, has three remarkable pathologic characteristics-senile plaque,neurofibrillar tangles and neuronal death. As a neurotrophic factor, basic fibroblast growth factor(bFGF)is closely related to AD. This article reviewed the interaction between bFGF and AD-associated gene products(such as amyliod ? protein,presenilin, apoloprotein E and microtubulin associated protein tau)and neuronal apoptosis. Some researchers suggested that bFGF may be put forward as potential therapeutic agent in AD and play a role in preventing or retarding the pathological process of this disease, alleviating or even eradicating the pathological insults of this disease.
3.POSTNATAL DEVELOPMENT OF S100B AND GFAP IN THE CENTRAL NERVOUS SYSTEM IN RATS
Jian JIN ; Zhuyi LI ; Hong LIN
Acta Anatomica Sinica 1955;0(03):-
Objective To study the expressions of S100B and glial fibrillary acidic protein(GFAP) in the central nervous system of Sprague-Dawley rats during postnatal development. Methods Twenty-four male SD rats were divided equally into four groups according to different postnatal times:7-day group,14-day group,21-day group and adult group.Immunohistochemistry was used to investigate the expressions of S100B protein and GFAP in the brain and the spinal cord. Results The amount and density of S100B positive astrocytes decreased significantly in frontal cortex,hippocampus,striatum,substantia nigra and spinal cord during postnatal development.It seemed that the second through the third week after birth was a critical period for these changes.The amount and density of GFAP positive AST increased gradually in the brain,but it was the opposite in the spinal cord.Double-labeled immunofluorescence of S100B and GFAP in hippocampus CA1 area showed that S100B positive stains were evenly distributed in the pyramidal,polymorphic and molecular layers from the seventh till the twenty first day after birth,but apparently decreased in each layer especially in the molecular layer in adult hippocampus while the immunoreactivities of GFAP increased.The proportion of double labeled cells also increased with the aging and more of them were found in the pyramidal and polymorphic layers.Conclusion Different patterns of the expressions of S100B and GFAP exist during postnatal development.It may reflect the different roles of these proteins on the glial cell development.And it may also indicate that the expressions of S100B and GFAP are regulated by different mechanisms during the course of development,which reflects the differentiation of subpopulations of astrocytes during ontogenesis.
4.Treatment of post operative complications of the procedure for prolapse and hemorrhoids
Chu-Yuan HONG ; Guo-Jian LIANG ; Jian-Sheng LIN ;
Chinese Journal of Primary Medicine and Pharmacy 2006;0(08):-
Objective To evaluate and analyze the postoperative complications induced from the procedure for prolapse and hemorrhoids(PPH).Methods The data of the third or fourth degree hemorrhoids operated by pro- cedure for prolapse and hemorrhoids were analyzed.Results Total 224 patients with hemorrhoids were operated on by PPH,and the mean operative time was 25 minutes and mean postoperative hospital stay were 3.5 days.Postoper- ative bleeding requiring haemostatic procedures occurred in two patients.Urine retention rate was 30.36%,there were 56 eases pain scores>5,there of re-prolapse,16 cases of residual skin tags.One case of mucocele.Conclusion The rule of PPH is individual management.
6.The expression of VEGF-C and MMP-7 in gastric carcinoma and their correlation with tumor invasion and metastasis
Shikai HONG ; Shaosen LI ; Yunfei LU ; Jinling LIN ; Qinghua LIAO ; Jian LIN ; Yuan HUANG ; Jian ZENG
Chinese Journal of General Surgery 1993;0(02):-
Objective To investigate the expression of vascular endothelial growth factor-C(VEGF-C) and matrix metalloproteinase-7(MMP-7) in gastric carcinoma and their correlation with tumor invasion and(metastasis).Methods Streptavidin peroxidase immunohistochemistry technique(SP)was used to detect the(expression) of VEGF-C and MMP-7 in 60 gastric carcinoma specimens,60 specimens of gastric mucosa(adjacent) to carcinoma,and 30 regional lymph node specimens.Results The positive expression rate of VEGF-C,MMP-7 in gastric carcinoma was markedly higher than that in normal gastric mucosa and gastric mucosa adjacent to carcinoma.The positive expression rates of VEGF-C and MMP-7 in metastatic regional lymph nodes were significantly higher than that in non-metastatic regional lymph nodes(P
7.Effect of basic fibroblast growth factor on radiation-induced splenocytic apoptosis of mice
An HONG ; Yanli XU ; Xiaokun LI ; Jian LIN ; Shuzheng LIU
Chinese Journal of Pathophysiology 1986;0(02):-
AIM: To investigate the effect of basic fibroblast growth factor (bFGF) on radiation-induced splenocytic apoptosis of mice. METHODS: At 14 h after whole body irradiation with 0.5 Gy and 1.0 Gy,splenocytes were cultured with and without bFGF,and splenocytic apoptosis was quantitatively analysed by flow cytometry. Cell proliferation was determined by the method of [3H]-TdR incorporation. RESULTS: bFGF(1 ?g/mL and 2 ?g/mL) could reduce the rate of cell apoptosis ,and promote the proliferation of splenocytes. CONCLUSION: bFGF could inhibit radiation-induced splenocytic apoptosis and promote the proliferation of splenocytes and then enhance body immunity.
8.Nursing cooperation of immediate breast reconstruction with the latissimus dorsi myocutaneous flap
Lin JIAN ; Heyu WU ; Xiao LIU ; Hong LIU
Modern Clinical Nursing 2016;15(4):12-14,15
Objective To summarize the experience of nursing cooperation for immediate breast reconstruction with the latissimus dorsi myocutaneous flap. Methods Twenty breast cancer patients underwent modified radical surgery with intraoperative immediate application of the latissimus dorsi myocutaneous flap in combination with the same period breast prosthesis for breast reconstruction. The nursing measures included preoperative preparation and mental support, intraoperative active cooperation, position care, sustaining of body temperature and strict aseptic and disease-free technology. Results All the breast cancer patients lived through breast cancer modified radical immediate breast reconstruction. No flap necrosis occurred , neither did obvious complications. The operations were satisfactory. Conclusion The key to the breast reconstruction for the breast cancer patients exists in preoperative psychological nursing , intraoperative strict aseptic and disease-free technology , the proper operation position and the correct use of instruments and equipment.
9.Alagille syndrome in 5 Chinese children.
Jian-She WANG ; Xiao-Hong WANG ; Zhong-Lin WANG
Chinese Journal of Pediatrics 2007;45(4):308-309
Alagille Syndrome
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pathology
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Child, Preschool
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China
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Female
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Humans
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Infant
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Male
10.Limbs anaesthesia caused by terbutaline sulphate solution for nebulization in a child.
Shu-Mei HUANG ; Jian-Jun LIN ; Xiao-Wei HONG
Chinese Journal of Contemporary Pediatrics 2009;11(4):Inside front cover-Inside front cover