1.The research and application on management system of cold chain facilities temperature control in the hospital
Guoli GONG ; Jian ZENG ; Feng GAN
China Medical Equipment 2016;13(5):9-11
Objective:To have a research and application on management system of cold chain facilities temperature control in the hospital and real-time monitor the temperature and humidity changes of cold-chain facilities.Methods: Based on RFID radio frequency, Internet of things and computer technology to realize the construction of the system hardware and software platform, through commissioning and case analysis for system improvement, the system was popularized and applied comprehensively.Results: After one year’s trial run, it showed that the system could accurately and effectively monitor the abnormal temperature and humidity of the hospital’s cold chain facilities and give the acousto-optic hint and remote alarm in time, effectively improving the management level of cold chain temperature control.Conclusion: The system could guarantee the fine management of the cold chain facilities temperature control, provide safe and traceable historical data, and put forward a new solution for building the quality and safety of cold chain facilities temperature control system.
2.Diagnosis and surgical treatment of primary malignant melanoma in esophagus
Dong CHANG ; Jian HU ; Min GONG ; Feng TIAN ; Tianyou WANG
Chinese Journal of Digestive Surgery 2013;12(10):801-803
Objective To investigate the pathological features,diagnosis and treatment of primary malignant melanoma in esophagus (PMME).Methods The clinical data of 3 patients with PMME who were admitted to the Beijing Friendship Hospital from January 2008 to June 2009 were retrospectively analyzed.All the patients received esophageal barium radiography,electronic fiberesophagoscopy,esophageal endoscopic ultrasonography,computed tomography,and underwent surgery.Adjuvant therapy and immunotherapy were applied postoperatively.Results The results of barium radiography showed irregular filling defect presentation in the distal esophagus.The results of endoscopy showed a purple black tumor with a length of 3-8 cm in the esophagus.The results of endoscopic ultrasonography showed that the tumor was derived from the mucosal layer with low echo density.The results of computed tomography showed thickness of the lower segment of the esophagus.All the 3 patients received left thoracic approach esophagectomy and esophagogastrostomy.Histopathology and immunohistochemistry confirmed malignant melanoma.The expressions of Mart-1,HMB-45 and S-100 antigen were positive.The survival time of 2 patients was longer than 3 years,and 1 patient died of metastasis 6 months after operation.Conclusions PMME is a kind of rare and malignant tumor with dismal prognosis.Surgical management is the first choice,adjuvant chemotherapy and immunotherapy are hopeful to increase the survival time of the patients.
3.Calcium-dependent modulatory effect of norepinephrine on the Ia antigen expression of the macrophage
Jian-Jun HUANG ; Fei-Li GONG ; Xin-Wei FENG ;
Chinese Journal of Immunology 1985;0(06):-
Fura—2 was used as a Ca~(2+) indicator to determine the intracellular calcium ion concentra-tion(〔Ca~(2+)〕i)of rat peritoneal macrophages(RPM?s),and APAAP enzyme immnoassay was ap-plied to detect the expression of Ia antigens on RPM?s.The results showed that norepinephrine(NE,10~(-9)mol/L)could markedly increase the〔Ca~(2+)〕i of the RPM?s(p
4.Comparative Study of Propofol and Isoflurane on Inflammatory Cytokines in Patients with Intracranial Neoplasm
Lufeng XU ; Wen PAN ; Jian GONG ; Feng GUO ; Rui FENG ; Wenyao CUI ; Fubin LV ; Chengjie GAO
Herald of Medicine 2014;(9):1157-1159
Objective To explore the neuroprotective mechanism of propofol by comparing the influence of propofol and isoflurane on inflammatory cytokines ( TNF-α、IL-1、ICAM-1 ) in patients with intracranial tumors. Methods One hundred and sixty-eight patients with intracranial neoplasm were randomly divided into two groups:the propofol ( Group P) and isoflurane (Group I),84 cases in each. Patients were given with propofol (3-6 μg·mL-1) by plasma target-controlled infusion or with continuously inhaled isoflurane ( 1%-2%) , respectively. The serum levels of TNF-α, IL-1 and ICAM-1 were detected before anesthesia and at 0,24,and 48 h after operation. Results The serum levels of TNF-α,IL-1 and ICAM-1 were significantly increased after operation as compared to baseline in both groups. The serum level of TNF-α was(69. 11±8. 95) and (76. 26±11.28) μg·mL-1,IL-1 was(21.57±3.19) and (29.58±4.38) ng·L-1,and ICAM-1 was (1.63±0.24)and (1.94±0.29) g·L-1 at 24 h post operation in Group P and Group I,respectively. These inflammatory cytokine levels were significantly higher in group I compared to group P at 24 and 48 h after operation (P<0. 05 or P<0. 01). Conclusion The target-controlled infusion of propofol brings about lower level of inflammatory reaction than isoflurane inhalation in patients with intracranial neoplasm,which may attribute to the mechanism of brain protection against injury.
5.Quality standard study on Mori Cortex liquid extract.
Mao-feng LIU ; Mei-ping XIE ; Lan LI ; An-qi LU ; Jian-gong SHI ; Su-juan WANG
China Journal of Chinese Materia Medica 2015;40(10):1850-1854
A reasonable and practicable quality standard was developed for mori liquid extract from different sources by TLC, HPLC and fingerprint technology. In TLC method, the compounds were separated on polyamide film using glacial acetic acid-water (1: 3) as mobile phase at a UV wavelength of 365 nm. All qualified samples had the spots of the same color as the control herb and substance. The RP-HPLC method was used to determine the content of mulberroside A with mobile phase of methanol-water (25: 75) at a wave-length of 326 nm. The mulberroside A was in good linear with a regression equation of Y = 46.965X (r = 0.999 6) in the range of 4.6 - 228 mg x L(-1). In 14 batches of samples, the mulberroside A in 4 batches of them was less than 0.5 g x L(-1), and was more than 2.0 g x L(-1) in the other batches. It was suggested that the content limit of mulberroside A should be no less than 1.5 g x L(-1). The HPLC fingerprints were evaluated by the similarities. It has found that the similarities of different mori liquid extracts were very low and the chemical diversity of mori cortex was the major factor of similarity. Moreover, the process impact was minimal. Thus the fingerprint was not included in this quality standard.
China
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Chromatography, High Pressure Liquid
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Disaccharides
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chemistry
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isolation & purification
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Drugs, Chinese Herbal
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chemistry
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isolation & purification
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standards
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Morus
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chemistry
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Quality Control
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Stilbenes
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chemistry
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isolation & purification
6.27 breast cancer patients treated with photodynamic therapy
Jian-Chun CUI ; Li LI ; Da-Qing RONG ; Qi DONG ; Qing-Feng LIU ; Ben-Song GONG ; Feng-Lan ZHANG ;
Cancer Research and Clinic 1999;0(05):-
Objective To investigate the methods and clinical significance of breast cancer treated with photodynamic.Methods From June to December in 2005,photodynamic therapy was used in 12 cases confirmed intramammary lymph node metastasis before operation and 15 cases confirmed chest wall recur- rences by means of lymph node imaging.Results The intramammary lymph node metastasis whose diameter between 0.5~1.0cm measured by lymph node imaging preoperatively completely disappeared when rechecked 3 months postoperatively.Chest wall recurrence regions of breast cancer whose diameter less than 1.0 cm completely remitted.Conclusion Photodynamic therapy is helpful to eliminate the intramammary lymph node metastasis and to cure the postoperative chest wall recurrence of breast cancer.
7.A medical image authentication method based on restorable watermarking.
Jian GONG ; Xiao-Yan ZHONG ; Qian-Jin FENG
Journal of Southern Medical University 2008;28(6):959-962
In this paper, a restorable watermarking algorithm is proposed for medical image content authentication. Important DWT coefficients are chosen to be coded with the SPIHT algorithm for generating watermarking. The improved security watermark scrambled by Arnold transformation was then embedded into the lower bits of the image data. Finally, the chain structure was used to detect the watermarking and identify the altered positions. The altered data in an image was restored by SPIHT decoding. The experimental results demonstrated that the watermarked image not only possessed good perceptual transparence but also allowed location and restoration of the tampered content.
Algorithms
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Biomedical Engineering
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Computer Security
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Diagnostic Imaging
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standards
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statistics & numerical data
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Image Interpretation, Computer-Assisted
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methods
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Medical Records Systems, Computerized
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organization & administration
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standards
8.Posterolateral approaches for treatment of pilon fractures.
Jian ZHANG ; Xie-Yuan JIANG ; Man-Yi WANG ; Xiao-Feng GONG ; Ting LI
China Journal of Orthopaedics and Traumatology 2013;26(1):59-63
OBJECTIVETo evaluate the effect and complication of surgical treatment for Pilon fracture using the posterolateral approach.
METHODSFrom August 2009 to March 2011, 15 patients with Pilon fractures (2 in B3,13 in C) and with a separate displaced posterior malleolar fragment was treated in two-stage: the first stage management was on stabiliztion of the soft tissue envelope with temporary external fixator of spanning arthritis, and the second stage management was open reduction and internal fixation with posterolateral approach and anteromedial or anteralateral approach.
RESULTSAll patients were followed-up for 12 to 17 months (14.2 months in average). Thirteen of the 15 fractures healed, but 2 fractures needed autologous bone graft procedure duo to nonuion. There was no wound complication related to poterolateral incion. Fourteen fractures had less than 2 mm of incongruity of distal tibia joint. According to Baired-Jackson criteria, the results were excellent in 2 cases, good in 7, fair in 4, and poor in 2.
CONCLUSIONThe posterolateral approach offers direct visualization for the reduction and fixation of the fibula and posterior distal fragment of the tibia Pilon fractures, faciliate the management of this difficult fracture pattern.
Adult ; Female ; Fracture Fixation, Internal ; methods ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Tibial Fractures ; surgery
9.Experience on enteral nutrition in short bowel syndrome.
Jian-Feng GONG ; Wei-Ming ZHU ; Ning LI ; Jie-Shou LI
Chinese Journal of Surgery 2007;45(13):894-897
OBJECTIVETo investigate the significance, effects and precautions of enteral nutritional support in patients with short bowel syndrome (SBS).
METHODSClinical data of 40 SBS patients who were maintained on enteral nutrition (EN) for more than 2 years were retrospectively summarized. The cost of EN and parenteral nutrition (PN), the PN-free duration, and the current nutritional status of these patients were analyzed.
RESULTSThe mean length of the remnant small bowel was (50.8 +/- 29.4) cm. All the patients currently lived on high-carbohydrate low-fat diet supplemented with EN (3284.0 +/- 1408.8) kJ/d, the cost was significantly lower than that of PN (P < 0.01). Mean PN-free duration was (29.1 +/- 9.2) months for these patients. The current defecation frequency and volume were (3.4 +/- 1.7) times/d and (720.2 +/- 350.3) ml/d, respectively. As for the patients' nutritional index, mean BMI, blood hemoglobin and serum albumin level were (17.8 +/- 3.2) kg/m(2), (113.3 +/- 14.8) g/L and (35.0 +/- 4.1) g/L, respectively.
CONCLUSIONSEnteral nutrition is a cost-effective method for maintaining the nutritional status in patients with short bowel syndrome, but proper management in clinical practice to avoid diarrhea or other complications should be ensured.
Adolescent ; Adult ; Enteral Nutrition ; Female ; Follow-Up Studies ; Humans ; Male ; Middle Aged ; Parenteral Nutrition ; Retrospective Studies ; Short Bowel Syndrome ; therapy ; Treatment Outcome
10.Real-time volume rendering based on gradient adaptive shading.
Jian GONG ; Zhao-qiang YUN ; An QIN ; Qian-jin FENG
Journal of Southern Medical University 2010;30(9):2156-2160
For medical image volume rendering, it is very difficult to simultaneously visualize interior and exterior structures while preserving clear shape cues. Highly transparent transfer functions produce cluttered images with many overlapping structures, while clipping techniques completely remove possibly important contextual information. To address this issue, A gradient adaptive shading based illumination model is proposed and implemented in CUDA architecture. The coefficients of ambient, diffuse and specular lighting are tuned adaptively according to gradient. The experiments show that our method is capable of preserving 3-D contextual information in medical image dataset while still show clear boundaries with real-time interactive speed.
Algorithms
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Artifacts
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Computer Graphics
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Computer Simulation
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Humans
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Image Enhancement
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methods
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Image Interpretation, Computer-Assisted
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methods
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Imaging, Three-Dimensional
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Models, Theoretical
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Pattern Recognition, Automated
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methods