Objective To study the catalytic capability of glucosamirie-Cu( Ⅱ) complex for decomposition of H2O2 and its relative factors. Methods Glucosamine-Cu( Ⅱ ) complex was prepared by the reaction of D-glucosamine hydrochloride with Cu2+ in aqueous solution, then added it into H2O2 solution. The concentration of H2O2 was determined by titrimetric analysis in a regular interval of time, the rate of decomposition of H2O2 was obtained in various conditions. Results Strong catalytic capability of glucosamine-Cu( Ⅱ ) complex was obtained at 30℃ pH 6. 5, the rate of decomposition was over 90% after 12h, and was almost 100% after 24h. Conclusion The complex of glucosamine-Cu( Ⅱ ) showed good catalytic capability for decomposition of H2O2.

Hepatocellular carcinoma is one of the most common malignant tumors.With the concealed characteristics and non-specific clinical expressions,its presence can be frequently missed,allowing progression to advanced stages where prognosis is poor.Therefore,early diagnosis is essential to improve the survival rate of patients with hepatocellular carcinoma.Recent developments in imaging technology and molecular biology are making strides in identifying and finding biomarkers of hepatocellular carcinoma,leading to earlier diagnosis.This article describes the latest developments,in combination with previous diagnostic methods to make a comprehensive examination of strategies for early diagnosis of hepatocellular carcinoma.

Research advances in pharmaceutical preparations of chitosan were reviewed in this paper, including peroral macromolecular drugs delivery system, pH-sensitive drug release system, targeting drug delivery system, nano-drug carriers, and so on.

Ear Protective Devices ; Follow-Up Studies ; Hearing Loss, Noise-Induced ; prevention & control ; Humans ; Male ; Mining ; Noise, Occupational ; prevention & control ; Petroleum ; Retrospective Studies

Dermatomyositis ; complications ; Humans ; Lung Diseases, Interstitial ; diagnosis ; etiology ; therapy

AlM: To explore clinical efficacy of hyperosmotic glucose after cataract surgery.METHODS: Eighty eyes ( 80 cases ) with ll level and above grades corneal edema after small incision cataract operation were enrolled. They were randomly divided into treatment group and control group. Control group used TobraDex eye drops and other conventional treatment and the treatment group received hyperosmotic glucose(500g/L) with the bases of the control group. The regression of corneal edema was observed by slit lamp microscope. SPSS 17. 0 statistical software was used for statistical analysis.RESULTS: The level of corneal edema at the first day after surgery, age, sexuality and nuclear hardness in the treated group were compared with those in the control group, the differences were without significances ( P>0. 05). Disappearance time of corneal edema was 4. 95 ± 3. 62d of the treatment group, and was 6. 80±3. 33d of the control group, the treatment group was better than control group (t=8. 55, P=0. 00).CONCLUSlON: Hyperosmotic glucose has exact and obvious efficacy for early corneal edema after cataract surgery.

Objective: To investigate the chemical constituents from the Seeds of Nelumbo nucifera. Methods: The chemical constituents were isolated by repeated silica gel chromatography, Sephadex LH-20 gel columns chromatography, medium pressure column chromatography, and semi-preparative liquid chromatography, and their structures were elucidated by chemical properties and spectroscopic analyses. Results: Thirteen compounds were identified to be p-methoxyphenylacetic acid (1), quercetin-3-O-α-L- arabinoside (2), apigenin-6-C-arabinoside-8-C-glucoside (3), naringenin (4), stigmast-4-en-3-one (5), quercetin-3-methyl ether (6), vitexin (7), cosmoslin (8), quercetin (9), apigennin (10), luteolin (11), kaempferol (12), and astragalin (13). Conclusion: Compounds 1-3, 5 and 6 are obtained from the plants of Nelumbo Adans for the first time, and compound 8 is obtained from Nelumbo plumula for the first time.

Objective: To compare the changes of seven kinds of compounds in the fruits, seeds, and peels of Gardeniae Fructus. Methods: Quantitative analysis of geniposidic acid, deacetyl asperulosidic acid methyl ester, genipin-1-gentiobioside, geniposide, chlorogenic acid, crocin I, and crocin II in the fruits, seeds, and peels of Gardeniae Fructus with rocessed and no processed, were firstly carried out by HPLC/DAD. Results: The conents of deacetyl asperulosidic acid methyl ester and chlorogenic acid were higher in the peels of Gardeniae Fructus. The conents of genipin-1-gentiobioside, geniposide, crocin I, and crocin II were higher in the seeds of Gardeniae Fructus. Geniposidic acid content was increased in turn, the content of deacetyl asperulosidic acid methyl ester, geniposide, chlorogenic acid, crocin I, and crocin II were reduced in turn and genipin-1-gentiobioside contents were not changed from crude, stir-fired, and stir-baked products. Conclusion: The contents of eacetyl asperulosidic acid methyl ester, genipin-1-gentiobioside, geniposide, chlorogenic acid, crocin I, and crocin II between the seeds and peels of Gardeniae Fructus exist differences. The main ingredients of Gardeniae Fructus are decreased after processing except the increasing of geniposidic acid.

Addiction diseases make patients dependent on drug abused or some kind of behavior, and seriously impair their physical and mental health. Drug therapy for this kind of disease has got increased attention in recent years besides non-drug treatment measures. Dependentless antileptic agents such as carbamazepine and phenytoin show their effective effects on some symptoms like withdrawal syndrome and craving. The mechanisms of addiction diseases and the drug's effects was discussed. Comparative study was made addiction disease and epilepsy.