1.Propofol associated with hypokalemia causes electro storm.
Jian-Hua YU ; Kui HONG ; Kai-Cheng CHENG
Chinese Journal of Cardiology 2007;35(11):1057-1057
3.Successful treatment of a patient with craniocervical penetrating injury by a steel bar.
De-zhi YU ; Jian-xin QIU ; Hong-wei CHENG
Chinese Journal of Otorhinolaryngology Head and Neck Surgery 2012;47(5):424-424
Adult
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Fluoroscopy
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Foreign Bodies
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therapy
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Humans
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Male
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Trauma, Nervous System
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therapy
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Wounds, Penetrating
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therapy
4.The Roles of Drug-Fluting Stents in the Prevention and Treatment of Restenosis After Extracranial and Intracranial Stent Angioplasty
Jian-Hong WANG ; Cheng CHEN ; Fu-Qiang GUO ;
International Journal of Cerebrovascular Diseases 2006;0(10):-
Now symptomatic extracranial and intracranial stenting usually uses bare metal stents, but the incidence of restenosis is higher.The studies of drug-eluting stems for the treatment of coronary atherosclerosis have suggested that the incidence of restenosis decreases significantly. Although extracranial and intracranial drug-eluting stem placement appears to be safe,further large,prospective,randomized,controlled trials are needed to demonstrate its safety and effectiveness.
5.Analysis of electric sacral neuromdulation and resiniferatoxin in treatment of primary female overactive bladder
Hua TANG ; Xiao-Qi LIAO ; Shun-Qin RAO ; Jian-Cheng HUANG ; Hong HUANG ; Shi-Yong HUANG ; Jian CHEN ;
Chinese Journal of Primary Medicine and Pharmacy 2005;0(11):-
Objective To analyze the efficacy of electric sacral neuromdulation and resiniferatoxin in patients with female overactive bladder.Methods 32 cases with IOAB female patients accepted percutaneous test sitmulation of the electric sacral nerves at S3 ,and treated by intravesical instillation with 100ml of 100nmol/L RTX.The effica- cy of voiding status were evaluated.The improvement of female patients life were evaluated comparing the rating of depression and anxiety.Results There were significant improvements in 32 cases in variables included the number of voiding,volume voided and signs every day and urgent uresis.In the rating of depression and anxiety,the patients improved a litter and still had stimulating symptom in urethra and bladder.Conclusion The treatment of IOAB with single administratoon of electric sacral neuromdulation and resiniferatoxin is effective,and can successfully im- prove the symptom with little side effects.
6.Total pancreatic head resection with duodenum and bile duct preserving: a report of 31 patients
Defei HONG ; Zhichuan LIN ; Yuhua ZHANG ; Yufeng CHEN ; Guoliang SHEN ; Jian CHENG ; Yi LU ; Jungang ZHANG
Chinese Journal of Hepatobiliary Surgery 2017;23(3):176-180
Objective To investigates the role of duodenum and bile duct preserving pancreatic head resection (DBPPHR) in treatment of benign or low-grade malignant diseases located in the head of pancreas.Methods The clinical data of 31 patients who underwent DBPPHR between April 2012 to May 2016 in Zhejiang Provincial People's Hospital and Zhangzhou Municipal Hospital of Fujian Province were analyzed retrospectively.Results Of the 31 patients,4 patients underwent laparoscopic DBPPHR.One patient in the open group was converted to pancreaticoduodenectomy.For the open group,the mean operation time was (165.3 ±63.6) min;the mean estimated blood loss was (258.1 ± 156.9) ml;and the mean postoperative stay was (11.7 ± 6.3) days.The postoperative complications included 1 reoperation due to postoperative bleeding,1 bile leakage and 13 patients developed grade A pancreatic fistula (48.2%).For the laparoscopic group,the mean operation time was 350.0 (280.0 ~ 450.0) min;the mean estimated blood loss was 425.0 (250.0 ~600.0) ml;and the mean postoperative stay was 14 days.Three patients developed postoperative pancreatic fistula (grade A).The pathological diagnosis were:12 patients with pancreatolithiasis,8 patients with serous cystadenoma,4 patients with branched intraductal papillary mucinous neoplasm,5 patients with neuroendocrine tumor and 2 patients with mucinous cystadenoma.The follow-up period was 1 ~ 48 month,and there was no patient with diabetes or diarrhea.Conclusions DBPPHR was safe and efficacious.It is less invasive to treat benign or low-grade malignant diseases located in the head of pancreas.
7.Expression of Potassium Channels in Peripheral Monocyte from Patients with Coronary Artery Disease and the Regulation of Simvastatin
Shaoping WANG ; Li YOU ; Shiying LI ; Jian WANG ; Hong YANG ; Shujuan CHENG
China Pharmacy 2015;(20):2793-2795
OBJECTIVE:To discuss the expression of voltage-gated potassium channel(KV1.3)and calcium activated potassi-um channel(KCa3.1)in peripheral monocyte from patients with coronary artery disease(CAD)and the regulatory effect of simvas-tatin. METHODS:20 patients with CAD and 8 control patients without CAD diagnosed by percutaneous coronary intervention but correlated to risk factor of CAD were enrolled. The expression of KV1.3 mRNA and KCa3.1 mRNA were measured by RT-PCR in 2 groups,and those of CAD group were measured by RT-PCR after 1 month of simvastatin treatment. RESULTS:Compared with control group,mRNA expression of KV1.3 [(1.54±0.08)vs.(0.77±0.06),P<0.01] and KCa3.1 [(1.32±0.08)vs.(1.06±0.06), P<0.05] were significantly increased in CAD group. mRNA expression of KV1.3 was significantly correlated to the concentration of C reactive protein (CRP)(P=0.003)and was decreased by simvastatin for one month [(1.54 ± 0.08)vs.(1.14 ± 0.05),P<0.01]. However,mRNA expression of KCa3.1 was not correlated to the concentration of CRP and simvastatin didn’t affect it’s expression. CONCLUSIONS:KV1.3 and KCa3.1 in peripheral monocytes may be two new markers of CAD. Regulating KV1.3 may be one of mechanisms of statin’s pleiotrophic effect.
8.Study on inhibitory effect of calycosin on hepatic stellate cell activation in rats by up-regulating peroxisome proliferator-activated receptor γ.
Jian PING ; Hong-yun CHEN ; Yang ZHOU ; Gao-feng CHEN ; Lie-ming XU ; Yang CHENG
China Journal of Chinese Materia Medica 2015;40(12):2383-2388
To observe the effect of calycosin on the proliferation and activation of primary hepatic stellate cells (HSCs) in rats, and prove calycosin shows the effects through peroxisome proliferator-activated receptor γ(PPARγ) and farnesoid X receptor (FXR). The results indicated that calycosin could inhibit HSC proliferation and expressions of activation marker smooth muscle actin-α and type I collagen. With the increase in HSC activation time, FXR expression reduced, but with no notable impact from calycosin. Calycosin could up-regulate PPARγ expression and its nuclear transition in a concentration-dependent manner. Its prohibitory effect on HSC activation could be blocked by PPARγ antagonist. In conclusion, calycosin could inhibit HSC activation and proliferation, which may be related with the up-regulation of PPARγ signal pathway.
Animals
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Cell Proliferation
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drug effects
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Cells, Cultured
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Drugs, Chinese Herbal
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pharmacology
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Hepatic Stellate Cells
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cytology
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drug effects
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metabolism
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Isoflavones
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pharmacology
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Male
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PPAR gamma
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genetics
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metabolism
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Rats
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Rats, Sprague-Dawley
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Receptors, Cytoplasmic and Nuclear
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genetics
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metabolism
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Up-Regulation
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drug effects
9.Ultrasound-guided methylene blue dyeing liver segmental resection for hepatocellular carcinoma
Guoliang SHEN ; Zhijie XIE ; Xiaoming FAN ; Jian CHENG ; Jia WU ; Defei HONG
Chinese Journal of General Surgery 2015;30(11):844-846
Objective To evaluate ultrasound-guided methylene blue dyeing for radical liver segmental resection.Methods Liver segmental resection with uhrasound-guide methylene blue dyeing (UMD-SR) was performed in 16 cases, results were compared with 16 conventional liver segmental resection (CSR) retrospectively.Results All the operations under uhrasound-guided methylene blue dyeing were successfully carried out, among them, reverse dyeing was used in cases with segment Ⅳ, Ⅴ, Ⅷ resection.The blood loss in UMD-SR group was much less than CSR group(t =3.011 ,P =0.009) , at the cost of a longer operation time (t =5.423,P =0.000 07).There was no difference in the mortality and morbidity rates between two groups.Tumor recurrence rate was 6.25% in UMD-SR group and 18.75% in CSR group (x2 =0.133,P =0.285).Conclusions Ultrasound-guided methylene blue dyeing liver segmental resection can reduce the blood loss during operation, improve the safety of hepatectomy in case of hepatic carcinoma.
10.Evaluation on medical statistics teaching by medical doctoral students
Yanfang ZHAO ; Hong MENG ; Cheng WU ; Jian LU ; Xiaojing GUO ; Rui WANG ; Jia HE
Chinese Journal of Medical Education Research 2013;(10):981-983,984
Objective To investigate the evaluation of medical doctoral students on medical statistics teaching. Methods An investigation was carried out among doctoral students of 2012 using questionnaires in a medical university. A total of 272 doctoral students were investigated and 266 (97.79%)of them had learned medical statistics before enrollment. Statistical description was used to analyze enumeration data by calculating cases and percentages. Results More than 88.00% of them thought that medical statistics was helpful for their future work. More than 60.00% of them thought that the present teaching contents were appropriate and about 93.00% of them thought that examina-tion mode was appropriate. However,65.00% of them thought that the class hours were not enough and some con-tents should be explained more clearly. Conclusions Both basic statistics methods and advanced statistics methods should be given consideration to. Some frontier or hot knowledge of medi-cal statistics should be arranged and the class hours should be increased to expand the content of teaching.