1.Study on portable neurogenic bladder curer
Chinese Medical Equipment Journal 1993;0(05):-
This paper presents a portable neurogenic bladder curer,which can produce a series of pulses according to human's physiology characteristic to stimulate bladder's points.Such bladder-related diseases can benefit from this curer as increased residual urine in the bladder,urine retention and urine incontinence.Being low-cost,small and portable,it can satisfy the needs of different patients.
2.Diagnosis and treatment of abdominal injuries after the Wenchuan earthquake
Chinese Journal of Digestive Surgery 2008;7(4):254-255
After analyzing the clinical data of 5 injured persons diagnosed with delayed spleen or liver rupture combined with fractures after the Wenchuan earthquake, we found that the abdominal injuries in earthquake were rare but usually very severe. Since almost all the injured persons had multiple injuries, mortality was extremely high. First aid service should be applied in the first 6 to 8 hours. Orderly physical examination and peritoneocentesis in multiple sites are in favor of diagnosis. Reducing the missed diagnosis rate of abdominal injuries is important in raising the rate of successful treatment. Therapy for earthquake injuries should be focused on the most deadly injuries after a thorough examination, besides this, precise employment of control surgery, swift transportation of the injured persons, and prevention and dealing with complications are also important.
3.Advances in research of NF-κB signal transduction in gastrointestinal cancer
Journal of International Oncology 2011;38(2):142-144
NF-κB a factor possessing multiple transcription functions, has been demonstrated to have relation with the imbalance between cell proliferation and apoptosis in stomach, intestines, liver and other tissues of digestive tract. The active NF-κB signal transduction is extensively involved in the precancerous lesion,rumor development and invasion and metastasis. The therapies aimed at the activation of NF-κB can promote apoptosis of tumor cells, reduce the resistance against chemo-radiotherapy and relieve the cachexia caused by tumor.
4.Relationship between the retinal changes of the fundus with pregnancy induced hypertension syndrome and prognosis of maternity and fetus
Zejun DAI ; Le DAI ; Yan ZHANG ; Jian LI
Journal of Chinese Physician 2001;0(02):-
Objective To explore the relationship between the retinal changes with pregnancy induced hypertension syndrome(PIH) and prognosis of maternity and fetus.Methods The fundus of 220 patients with moderate and severe PIH were examined and analyzed.Results All patients had fundus changes and the fundus changes were positively related with the degree of PIH(P
5.Anti-arrhythmic research situation and thinking of traditional Chinese medicine monomer.
China Journal of Chinese Materia Medica 2014;39(8):1544-1546
The basic physiological function of anti-arrhythmic drugs is affects myocardial cell membrane ion channels. Change the ion flow and affect cell electrophysiological properties, change the conduction velocity, eliminate retrace, inhibit autorhythmicity and trigger events, inhibit the occurrence of arrhythmia, but will trigger a new activities, new retrace, produce new arrhythmia. In recent years, with the improvement of the theoretical system of traditional Chinese medicine and the production of new research methods, Chinese medicine treatment of arrhythmia has a new development. This article summarized the recent decades of which Chinese medicine monomer anti-arrhythmic drugs that had been proved by the influence of monomer anti-arrhythmic drugs, lists the differents traditional Chinese medicinal materials which chemical composition and the effective of the anti-arrhythmic effects, shows the unique advantages of Chinese medicine in the aspect of anti-arrhythmic, and points out that the current Chinese medicine in anti-arrhythmic (monomer) existing problems and solutions.
Anti-Arrhythmia Agents
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therapeutic use
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Arrhythmias, Cardiac
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drug therapy
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Biomedical Research
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Drugs, Chinese Herbal
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therapeutic use
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Humans
6.STUDY ON THE TREHALOSE STRESS PROTECTION ON STREPTOCOCCUS THERMOPHILUS AND LACTOBACILLUS PLANTARUM
Xiuyu DAI ; Yiguo SHEN ; Jian ZHOU
Microbiology 2001;28(2):46-50
The viability of freeze-dried cells of Streptococcus thermophilus and Lactobacillus plantarum by adding different stabilizer and protectants such as skim milk, sucrose and trehalose were investigated. When the bacteria were dried with 150mmol/L trehalose,75% of S. thermophilus and 33% of L. plantarum cells were survived, comparing with control of 19% and 1% respectively. When S. thermophilus was exposed at 90℃, the cells with trehalose increased tolerance to high temperature. When S. thermophilus freeze-thawing for 4 and 8 cycles, the survival was much higher than that of without trehalose protected. Scanning Electro-microscope pictures showed that the cells with trehalose, appeared as normal, but those without the sugar were broken or collapsed. The data confirmed that the disaccharide could protect bacteria against stress conditions.
7.A clinical trial of duo positive airway pressure ventilation versus nasal continuous positive airway pressure in treatment of preterm infant with neonatal respiratory distress syndrome after INSURE
Liying DAI ; Jian ZHANG ; Lili WANG
Journal of Clinical Pediatrics 2014;(8):732-735
Objective To explore the efficacy of duo positive airway pressure ventilation in treating preterm infant with neonatal respiratory distress syndrome (RDS). Methods 65 preterm infants admitted to the neonatal intensive care unit from December 2012 to December 2013 were randomly divided into DuoPAP group (34 cases) or NCPAP (31 cases) group. Blood gas analysis(pH value, PaO2, PaCO2 and OI) at 1h, 12h, 24h, and 72h, and incidence of apnea, pulmonary air leak, repeated application of pulmonary surfactant and non-invasive ventilation failure at 72h in the two groups were measured and compared after using intubate surfactant extubate (INSURE). Results OI after non-invasive ventilation at 1h, 12h, and 24h was signiifcantly higherin DuoPAP group than that in NCPAP group P<0.01). PaCO2 after non-invasive ventilation at 1h, 12h, 24hand 72h was signiifcantly lower in DuoPAP group than that in NCPAP group (P<0.01). PaO2 after non-invasive ventilation at 1h and 12h was higher in DuoPAP group than that in NCPAP group, and there was signiifcant difference between the two groups (P<0.01). The incidence of non-invasive ventilation failure, apnea in 72h was lower in DuoPAP group than that in NCPAP group, and there was signiifcant difference between the two groups (P<0.05). Conclusions Compared with NCPAP, DuoPAP is more feasible for improving oxygenation, decreasing the need for mechanical ventilation in 72h in preterm infants with neonatal RDS.
8.Experimental technology and methods of lymphatic metastasis in gastric cancer
Jian DING ; Xiaojun DAI ; Xiaochun ZHANG
Journal of International Oncology 2013;(3):219-222
With the development of imaging technique and molecular biological technique,researchers all over the world have made a great many of studies on the mechanism and treatment of lymphatic metastasis.The discovery of lymphatic endothelial cell-specific markers make it clear to distinguish lymphatic endotheliocyte.The application of new techniques such as immunohistochemical method and reverse transcription polymerase chain reaction (RT-PCR) can study the lymphatic metastasis from the genetic and molecular level.The application of molecular imaging and nanoparticles could provide new detection methods and therapies.The establishment of animal models offers a solid foundation for experimental study.
9.Pyogenic liver abscess: a clinical analysis of 118 cases
Jian GONG ; Wei DAI ; Zhigang PAN
Chinese Journal of General Practitioners 2013;(3):211-213
The clinical data of 118 patients with bacterial liver abscess admitted to a tertiary hospital from January 2007 to December 2009 were analyzed retrospectively.Etiology study showed that 45.8%(54/118) cases of bacterial liver abscess were cryptogenic,40.7% (48/118) were biliary source and 13.5% (16/118) were hematogenous.The positive rate of pus culture was 57.1% (36/63),among which klebsiella pneumoniae accounted for 72.2% (26/36).The positive rate of blood culture was 31.2%(20/64) and klebsiella pneumoniae accounted for 95% (19/20).One hundred and sixteen patients (98.3%) underwent color ultrasound examination with an accuracy rate of 93.2%.84 patients (71.2%)underwent the CT scan with an accuracy rate of 95.3% and 20 patients underwent MRI with an accuracy rate of 85%.Seventy five patients (63.6%)accepted ultrasound-guided percutaneous aspiration and catheter drainage combined with antibiotic therapy; 40 patients(33.9%)were treated with antibiotics alone.On the discharge 27 patients(22.9%) achieved clinical cure,87 patients (73.7%) were classified as effective,4 patients (3.4%) had no effect and no death in this group of patients.The average length of hospital stay was 16 days.Cryptogenic was the most common cause of bacterial liver abscess,biliary source took the second place.Kleibsiella pneumoniae was the predominant organism.Detailed medical history inquiry,physical examination and assistant examination may increase the accuracy rate of diagnosis.Needle biopsy should be performed if necessary.Ultrasound-guided percutaneous aspiration and catheter drainage combined with antibiotics should be the first-line treatment.
10.Clinical manifestations of pyogenic liver abscesses of cryptogenic origin
Jian GONG ; Wei DAI ; Zhigang PAN
Chinese Journal of General Practitioners 2013;(7):553-555
Total 118 patients with pyogenic liver abscess admitted to Zhongshan Hospital were classified into pypgenic liver abscesses of cryptogenic origin (PLAC,n =54),pyogenic liver abscesses of biliary origin (PLAB,n =48) and pyogenic liver abscesses of hemagenous origin (PLAH,n =16)according to the causes.The clinical features of three groups were compared and analyzed.The results showed that no statistically significant difference existed among three groups in clinical manifestation and signs.Compared to PLAB,the abscesses in right lobe of liver were more common in PLAC,diabetes mellitus was more prevalent in PLAC,but the co-existing diseases including chronic liver disease,non biliary malignant tumor and ALP elevation were less in PLAC.Klebsiella pneumoniae was frequently detected in PLAC,but there was no significant difference comparing to other two groups.No significant difference was found among three groups in the choice of therapeutic methods,the course of antibiotics,length of hospital stay and the days from admission to diagnosis.