1.Effect of continuous venovenous haemodiafiltration on the clearances of various solutes in multiple organ dysfunction syndrome dogs
Jihong CHEN ; Che YU ; Jian LIU
Chinese Journal of Nephrology 2011;27(2):124-127
Objective To study the effect of continuous venovenous haemodiafiltration (CVVHDF) on the clearances of various solutes in multiple organ dysfunction syndrome (MODS)dogs.Methods Dogs were subjected to hemorrhagic shock plus resuscitation and endotoxemia to set up MODS model,then they were randomly divided into 2 groups: MODS group (M group)and MODS+CVVHDF group (M+C group).A PRISMA pre-dilution system with AN-69 filter was applied.Solute clearance of nitric oxide(NO),urea nitrogen(UN),creatinine (Cr),interleukin-6 (IL-6),interleukin-10 (IL-10),tumor necrosis factor-α (TNF-α) and endotoxin (LP) was determined with same dialysate and ultrafiltrate volume during CVVHDF.The clearance of various solutes (Kd) was calculated by the concentration of the cleared solutes in effluents (E) based on the formula Kd=(ExQE)/P.Results Clearances of NO,UN,Cr were greater than those of IL-6,IL-10,TNF-α,LP during the treatment of CVVHDF.Conclusion CVVHDF could effectively reduce the levels of various solutes in the development of MODS by convection and absorption.
2.Effects of Zhike Qingfei Oral Liquid on Inflammatory Cells,Interleukin-8 and Tumor Necrosis Factor-? in the Sputum in 25 Cases of Chronic Obstructive Pulmonary Diseases
Hongzhu CHE ; Jian PANG ; Changjian LI ;
Journal of Traditional Chinese Medicine 1993;0(10):-
Objective:To observe the role of Zhike Qingfei Oral Liquid in treatment of the airway inflammation of chronic obstructive pulmonary diseases(COPD).Methods:50 cases with COPD at stable stage were divided into a treatment group and a control group,25 cases in each.Patients in both groups were treated with conventional therapy,including oxygen therapy,cardiactonic diuresis and relieving cough and asthma,etc.Zhike Qingfei Oral Liquid was added to the patients,of the treatment group,20ml each time,3 times each day,for 6 weeks.Clinical scores,pulmonary function,cell count and classification,interleukin-8(IL-8)and tumor necrosis Factor-?(TNF-?)in the sputum before and after treatment were investigated.Results:In the treatment group.the clinical score,FEV_1 and FEV_1/FVC(%)improved significantly(P
3.Video-assisted thoracoscopic treatment of spontaneous pneumothorax
Haitao CHEN ; Jian REN ; Jiaming CHE
Journal of Interventional Radiology 1994;0(04):-
Objective To propose a treatment protocol by videothoracoscopy in spontaneous pneumothorax. Methods One hundred and three patients underwent Video assisted thoracoscopic (VATS) treatment of spontaneous peumothorax and hemothorax. Indications included recurrent pneumothorax, persistent air leakage following conservative therapy, complicated hemothorax and CT scan identified bullae formation. Results No operative deaths occurred, conversion rate was 2.91%, recurrence rate was 0.97%, complication rate was 3.81% and mean postoperative hospital stay was 5.6 days. Conclusions VATS treatment of spontaneous pneumothorax is better than open chest surgery and also superior than conservative therapy.
4.Interventional effect of oral negative pressure on chronic pharyngitis and its influence on nail fold microcirculation
Rang LI ; Jianbin CHE ; Jian ZHANG ; Xiaohong MU ; Yankai LIU
Chinese Journal of Tissue Engineering Research 2006;10(36):173-175
BACKGROUND: Microcirculation disturbance of pharynx may be one of the pathogenesis base caused recurrent attacks of chronic pharyngitis. The negative pressure can improve the microcirculation of inflammary target organs by biomechanical changes.OBJECTIVE: To explore the therapeutic effect of oral negative pressure on patients with chronic pharyngitis and nail fold microcirculation.DESIGN: A randomized single blind controlled observation.SETTING: Department of Pathophysiology of Hebei North University.PARTICIPANTS: A total of 65 patients with chronic pharyngitis and course of disease about 1-3 years admitted to Department of Neurology,First affiliated Hospital of Hebei North University from January to September 2002 were selected. They were randomly divided into treatment group (n=35) and control group (n=30), including 36 cases with chronic pharyngitis (18 cases from the treatment group, 18 cases from the control group), 29with chronic hypertrophied pharyngitis (17 cases from the treatment group,12 cases from the control group).METHODS: The Hices oral negative pressure instrument was used and the negative pressure exert equipment was put into the optimal position of the patients' mouth to keep the negative pressure of (0.05±0.01) Mpa, 10minutes once (the first therapy time was 5 minutes), once daily and the time was fixed, 5 days as a period of therapy for three periods. Patients in the control group were also given the negative pressure exerts equipment,but no negative pressure was exerted.MAIN OUTCOME MEASURES: ① Observation and evaluation of nail fold microcirculation: The nail fold microcirculation was observed by the XTL- Ⅱ microcirculation micro-television system, and the first row nail fold of the left ring figure was checked conventionally to record the state of microvessel, state of micro-bloodstream and peri-loop. The degree of microcirculatory disturbance was quantitatively analyzed according to Tian Niu's weighing integral method, the lower the scores, the better the microcirculation. ②The improvement of chronic pharyngitis after treatment of 3courses.RESULTS: Totally 65 patients with chronic pharyngitis entered the stage of result analysis. ①After 1 course of treatment, the symptoms of 1/3 of the patients in the treatment group were significantly improved; after 3 courses of treatment, except there was no obvious changes of hypertrophied morphology such as lymphatic follicle proliferation on posterior wall of throat and hypertrophy on side cable of throat, the pathological signs and prevalence of mucosa congestion were obviously lower than those before treatment and the control group (P < 0.05-0.01) effective rate was 88.6%.②) Improvement of microcirculation disturbance with chronic pharyngitis was evident, restoring to basically normal from medium degree abnormality before treatment, the total score values reduced to 1.941 ±0.165 from 4.836±0.242 (P < 0.01).CONCLUSION: Oral negative pressure can significantly release or eliminate the symptoms and signs of chronic pharyngitis, which may relate to improvement of microcirculation disturbance.
5.Observations on the Efficacy of Electroacupuncture plus a Multi-function Cervical Rehabilitation System in Treating Cervical Spondylosis
Zheng HUANG ; Qiping DAI ; Jian SUN ; Yunpeng WU ; Tao CHE
Shanghai Journal of Acupuncture and Moxibustion 2015;(11):1088-1090
Objective To investigate the clinical efficacy of electroacupuncture plus a multi-function cervical rehabilitation system in treating cervical spondylosis.Methods Sixty patients with cervical spondylosis were randomly allocated to treatment and control groups, 30 cases each. The treatment group received electroacupuncture plus treatment with a multi-function cervical rehabilitation system and the control group, electroacupuncture alone. After 30 days of treatment, changes in the pain score, the neck disability index, and cervical active range of motion and isometric muscle strength were observed in the two groups and the clinical therapeutic effects were compared between the two groups.Results The total efficacy rate was 96.7% in the treatment group and 93.3% in the control group; there was no statistically significant difference between the two groups (P>0.05). There were statistically significant pre-/post-treatment differences in the pain score, the neck disability index, and cervical active range of motion and isometric muscle strength in the two groups (P<0.01,P<0.05). There were statistically significant post-treatment differences in the neck disability index, and cervical active range of motion and isometric muscle strength between the treatment and control groups (P<0.05).Conclusions Electroacupuncture plus a multi-function cervical rehabilitation system is an effective way to treat cervical spondylosis. It can relieve the clinical symptoms in the patients.
7.Evaluation on the effect of competency based education practice teaching model of vocational nursing students with ability training
Ping JIAN ; Chun YANG ; Xiaoqiong CHE ; Fei PAN ; Deyu QIN
Chinese Journal of Medical Education Research 2017;16(5):522-526
Objective To discuss the effect of competency based education practice teaching model on vocational nursing students with ability training.Methods Totally 96 vocational nursing students were divided into control group from July 2014 to May 2015,receiving routine mentoring teaching mode and totally 99 vocational nursing students were divided into learning group from July 2015 to May 2016,receiving competency based education practice teaching model.Theoretical examination and clinical operation skill test as well as self evaluation of caring ability and transitional nursing ability were conducted to both groups after the course to compare the test scores and the change of their caring ability and transitional nursing ability.SPSS 19.0 was used for statistical analysis,and independent samples t test was used between the two groups.Results The theoretical scores of the nursing students in the experimental group ([93.70 ± 4.27) vs.(88.00 ± 4.83)] and skill test [[95.70 ± 2.49] vs.(91.40 ± 2.87)] were higher than those of the control group;caring ability score [(189.3 ± 13.5) vs.(179.4 ± 10.4)],with the average score of cognitive dimension (51.6 ± 9.8) vs.(50.2 ± 10.3)],the dimension of courage (70.2 ± 6.5) [vs.(65.7 ± 8.4)],average patient dimension (63.4 ± 4.8) vs.5.4)];transitional nursing ability score [(124.95 ± 24.06) vs.(118.18 ± 20.41)],the dimension of knowledge sharing [(38.43 ± 8.22) vs.(36.08 ± 7.23)],average score of attitude dimension [(54.08 ± 10.66)vs.(51.02 ± 9.16)],average score of behavior dimension [(32.43 ± 6.25) vs.(32.43 ± 6.25)],which were all increased compared with the control group,and the difference was statistically significant.Conclusion Competency based education practice teaching mode achieves good teaching effect and it is worth recommending in clinical teaching.
8.Evaluation of early emergency care process for severe pelvic fractures combined with multiple trauma
Jian LU ; Yongbing QIAN ; Feng XIA ; Kanglong YU ; Ruilan WANG ; Yongmei CHE
Chinese Journal of Trauma 2012;28(4):296-300
Objective To evaluate the early emergency management process for severe pelvic fractures combined with multiple trauma. Methods The study involved 113 patients with severe pelvic fractures combined with multiple trauma treated from January 2007 to May 2011.The patients were divided into two groups,ie,before trauma team establishment (26 patients treated from January 2007 to May 2008) and after trauma team establishment (87 patients treated from June 2008 to May 2011 ) in accordance with the establishment period of trauma team in June 2008.The mortality was compared before and after application of trauma-team-based algorithm with damage control resuscitation,external fixation and angiographic embolization.Variables including age and gender distribution,ISS score,injury type and mechanism,transportation time,associated injury number,initial systolic pressure hemoglobin and blood transfusion were analyzed for study of their relation with mortality. Results After trauma team establishment,the mortality (23%) was significantly lower than before trauma team establishment (46%).The mortality showed significant relation to ISSN score and over two regions of associated injury,but showed no correlation with age and gender distribution,injury type and mechanism,transportation time initial systolic pressure hemoglobin,and blood transfusion. Conclusion The application of trauma team is effective in treatment of severe pelvic fractures combined with multiple trauma and can decrease the mortality.
9.Observation on therapeutic effect of plum-blossom needle therapy on peripheral facial neuritis at acute stage.
Chinese Acupuncture & Moxibustion 2005;25(12):851-852
OBJECTIVETo compare difference between plum-blossom needle therapy and hormonotherapy in the The treatment group of 32 cases with periphtherapeutic effect on peripheral facial neuritis at acute stage.
METHODSeral facial neuritis at acute stage were treated with plum-blossom needle therapy and the control group of 32 cases with oral administration or intravenous drip of dexamethasone. Their therapeutic effects were compared.
RESULTSThe total effective rate was 100.0% in the treatment group and 93.4% in the control group, with a significant difference between the two groups (P < 0.05).
CONCLUSIONThe therapeutic effect of plum-blossom needle therapy on peripheral facial neuritis at acute stage is better than that of the hormonotherapy.
Acupuncture Therapy ; Facial Nerve Diseases ; Flowers ; Humans ; Needles ; Prunus domestica
10.Brief analysis on characteristics of professor Tian Wei-Zhu's needling manipulation.
Chinese Acupuncture & Moxibustion 2006;26(8):583-586
Professor Tian Wei-zhu, a national famous expert of acupuncture and moxibustion, has consummate skill, profound theory, and does not stick to routine method in diagnosis and treatment, with rich clinical experiences and comprehensive and profound medical theories, forming own academic characteristics. In the present paper, the experiences were expounded, summarized and systematized in detail from the 4 aspects: basic training of physicians before acupuncture, especially, training of needling manipulation and emphasizing the concept of treating spirit, paying attention to coordination of the physician and patients; main points of needle insertion of no-pain at manipulation; about arrival of qi, method of inducing propagation of needling sensation.
Acupuncture
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Acupuncture Therapy
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China
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Humans
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Moxibustion
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Needles
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Sensation