1.The Effect of Traditional Culture on the Development of Traditional Chinese Medicine and the Measures of Strengthening the Cultivation of Humanistic Spirit
Pinghua SUN ; Lian LIU ; Zhixiong ZHAO ; Jing LIN ; Jialiang GUO
Chinese Medical Ethics 2017;30(6):697-700
Chinese traditional culture is the soil for the survival and development of traditional Chinese medi-cine,among them,the concept of A thing is valued if it is rare portal factions and master has influenced the development,communication and popularization of traditional Chinese medicine.But the spirit and thinking of harmony unity of heaven and man comparative state benevolence and self-cultivation and self-re-straint has played an active role in the development of traditional Chinese medicine.Thus this paper put forward the suggestions and opinions of strengthening the cultivation of humanistic spirit of higher traditional Chinese medi-cine talents:establishing a comprehensive evaluation standards of higher traditional Chinese medicine talents,es-tablishing scientific development concept to treat the inheritance and innovation of traditional Chinese medicine cul-ture,perfecting the curriculum provision of relevant professions,creating the conducive environment for the trans-mission of traditional Chinese medicine culture,hoping to provide a reference for the explanation of the relationship between traditional culture and traditional Chinese medicine.
2.Quantitative determination of the absolute content of quercetin by proton nuclear magnetic resonance
Wenxia SUN ; Jialiang ZHONG ; Jiawei HOU ; Guangdong WANG ; Haijun HAO
Drug Evaluation Research 2017;40(1):59-62
Objective To establish a novel method to determine the absolute content of quercetin by proton nuclear magnetic resonance (qNMR).Methods DMSO-d6 was employed as solvent,and maleic acid as an internal standard.Proton signal peaks at δ7.50-7.58 and δ6.26 of maleic acid were served as quantification peaks.The content of quercetin is determined with qNMR in comparison with the results obtained by mass balance method.Results Linear regression of quantitative peak areas ratio (As/Ar) of quercetin-maleic acid vs mass ratio (ms/mr) yielded a correlation coefficient of 0.999 3 and a regression equation ofy =2.963 x + 0.134 1.The contents of three batches quercetin were 85.20%,84.93%,and 85.27%,the average was 85.13% and its RSD was 0.21%.The results were generally consistent with that of mass balance methods.Conclusion This method was easy and simple to handle,and the analysis results were accurate.It could be the complementary for the mass balance method.
3.Cementless total hip arthroplasty with structural allograft for massive acetabular defect in hip revision
Jialiang TIAN ; Li SUN ; Ruyin HU ; Xiaobin TIAN
Chinese Journal of Traumatology 2014;(6):331-334
Objective: To study retrospectively 20 hip revison patients treated by cementless total hip arthroplasty with structural allograft.
Methods: Twenty patients suffering from aseptic loosening of an uncemented cup complicated by a large defect underwent cementless total hip arthroplasty with structural allograft and were followed up for at least 5 years. Clinical results were evaluated by Harris score and leg length measurements. Radiographic analysis included implants migration, graft absorbance, osteolysis and liner wear.
Results: No cup loosening or graft reabsorption was found at final follow-up. Clinical improvements in pain and functional status were demonstrated during the follow-up period. The mean Harris hip scores improved from 29 preoperatively (range 20-41) to 81 postoperatively (range 73-89).
Conclusion: Our study shows that cementless total hip arthroplasty with allograft is a good way for massive defect in acetabular bone stock.
4.Clinical research of transvaginal repair of cesarean scar diverticulum
Min YAO ; Huihui CHEN ; Jie TAO ; Yu LI ; Minghua SUN ; Jialiang ZHU ; Ping CHEN ; Xipeng WANG
Chinese Journal of Obstetrics and Gynecology 2015;(7):500-504
Objective To explore the clinical effect of transvaginal repair of cesarean scar diverticulum (CSD). Methods Totally 64 patients of CSD in the First Maternity and Infant Hospital, Tongji University between Mar. 2013 and Sept. 2014 underwent transvaginal repair of CSD were reviewed retrospectively and followed. Result All the patients had a prolonged period, and the duration was (14.8± 3.5) days; all the patients were received the transvaginal repair of CSD, there was no intra-operative complications, the procedures were successfully performed in all patients. The mean operation time was (67± 12) minutes, the mean blood loss was (53±32) ml, and the mean length of hospital stay was (4.0±1.1) days. All patients were followed after the operation, the duration of menstruation was (8.1 ± 3.5) days shorter in average, which was statistically significant (P<0.01);the operation effective rate was 94%(60/64) to assess the clinic syptoms, the operation effective rate was 95%(61/64) for anatomic assessment. The distance of the CSD from the serosa became thicker after surgery significantly, the distance was thicker (3.4 ± 0.4) mm compared with preoperation (P<0.01). Conclusions Transvaginal repair of CSD offers minimal invasiveness, good exposure and accurate resection. It is worth to be popularized in the treatment of patients with CSD.
5.Bone cement spacers and Link spacers for treatment of infection due to total hip arthroplasty:a comparative study
Li SUN ; Xiaobin TIAN ; Ruyin FU ; Jialiang TIAN ; Wei HAN ; Zhaocheng LIU
Chinese Journal of Trauma 2012;(11):1014-1018
Objective To compare the efficacy of self-made bone cement spacers containing vancomycin(vancomycin spacer)and Link infection-treating spacers(Link type spacer)for chronic infection after total hip arthroplasty(HTA)and investigate the choice of spacers for the two-stage revision of infection.Methods The study included 26 patients with infection combined with HTA,aged 32-82 years(mean 69.5 years).In the first stage,after complete debridement and removal of infected prostheses,the vancomycin spacers were implanted in 14 patients,while the Link type spacers were implanted in the rest 12 patients.Two weeks of intravenous administration of antibiotics and then six weeks of oral administration of antibiotics were done postoperatively.White blood cells(WBCs),erythrocyte sedimentation rate(ESR)and C-reactive protein(CRP)were measured periodically after operation.THA revision was performed in the second stage.Clinical outcomes were evaluated according to the pre-and post-operative Harris hip score.Results All patients obtained primary healing of incision after complete debridement,removal of prostheses and implant of the vancomycin spacers or the Link type spacers.Two-stage revision surgery was performed at 3-11.5 months after the one-stage surgery(mean 5.2 months).The follow-up ranging from 12 to 33 months(mean 20.8 months)manifested no signs of reinfection.The mean Harris hip score was increased from 27.9 points before one-stage operation to 52.9 points before two-stage operation,and 83.6 points at the latest follow-up(P<0.05)One of 12 vancomycin spacers was broken before the revision surgery,as was free from the Link spacers.Conclusions(Ⅰ)Two-stage revision is an effective method in the treatment of infection after HTA because of high eradication rate of infection,effective pain relief and good postoperative functional result.(2)The vancomycin spacers and the Link type spacers can both effectively control infection and restore part of limb function.(3)The Link type spacers take advantages of simple in operation and the function improvement of the limbs during the intermittent period of treatment,but disadvantages of the catheters being prone to block,limited slow release of antibiotics and high cost of treatment.Thereby,the Link type spacer is suitable for the patients with relatively strong constitution,little serious infection,or high requirement of limb functions at the interval of two operations.
6.Relationship research between expression of HPV L1 capsid protein and cervical lesions degree
Jialiang GAO ; Wenhu CHEN ; Aihua SUN
Chinese Journal of Experimental and Clinical Virology 2016;(1):34-36
Objective To investigate the clinical significance of the expression of Ll capsid protein in cervical lesion cells infected with human papillomavirus ( HPV) , for the prevention of cervical cancer and suggestion of progression and probability of potential lesions.Methods 259 different levels of cervical lesion patients were patients group, including 103 cases negative for intraepithelial lesion and malignancy ( NILM) , 91 cases with atypical squamous cells of undetermined significance( ASCUS) ,36 cases with low-grade squamous intraepithelial lesion ( LSIL ) , 23 cases with high-grade squamous intraepithelial lesion ( HSIL) , and 6 cases with squamous cell carcinoma ( SCC) .Cervical cell samples of 50 normal physical examination people were control group.Immunohistochemical staining for Ll capsid protein and PCR-based reverse blot hybridization for 23 HPV DNA were employed.Results Both Ll capsid protein detection and PCR-based reverse blot hybridization detection were negative in the control group.The infection ratio of HPV were 23.3%, 69.2%, 83.3%, 87.0%and 100%in woman with NILM, ASCUS, LSIL, HSIL and SCC, respectively.The constituent ratio of high-risk HPV ( HR-HPV) were 79.2%, 92.1%, 96.7%, 100%and 100%in HPV positive patients with NILM, ASCUS, LSIL, HSIL and SCC, respectively.The positive rates of HPV Ll capsid protein in NILM, ASCUS, LSIL, HSIL and SCC were 25.2%, 31.9%, 63.8%, 17.4%and 0.0%, respectively.Conclusions Both infection ratio of HPV and constituent ratio of HR-HPV were increased gradually with the aggravation of cervical lesions, and the infection ratio of HPV and constituent ratio of HR-HPV were closely related to the degree of cervical diseases.The detection results of Ll capsid protein were on the rise in the early phase of cervical lesion,however,declining in the late phase of cervical lesion, the expression of HPV Ll capsid protein associates with the degrees of cervical lesion, which may serve as an indicator of cervical precancerous lesions of the follow-up.
7.Application of beach chair position and lateral decubitus position in shoulder arthroscopy
Haifeng HUANG ; Jialiang TIAN ; Li SUN ; Xianteng YANG ; Yukun SHEN ; Zhihui YAN ; Shanshan LI ; Xiaobin TIAN ; Quan XIE
Chinese Journal of Orthopaedics 2017;37(12):756-762
The clinical application of arthroscopic minimally invasive treatment of shoulder joint disease technology has become a routine,and it has been widely carried out around the world.Compared with the traditional open surgery,it only needs to establish a few channels in the shoulder and then the diagnosis and treatment of the structure under the acromion and glenoid joint internal lesions can be completed through the arthroscopic technique under direct vision,of course,including local collection of pathological specimens.Shoulder arthroscopic surgery has the advantages of simple operation technique,small economic burden of patients,small tissue trauma,quick recovery and high accuracy of disease diagnosis.At present,there are two main options for shoulder arthroscopy:the beach chair position (BCP) and the lateral decubitus position (LDP).The choice of surgical position for surgeons is closely related to the intraoperative operation,the risk of complications,the efficacy of surgery,and the cost of setting the posture.Shoulder arthroscopy of these two positions have their own advantages and disadvantages:in the BCP,the surgeon gets a better anatomical operation experience,if necessary,can be converted into open surgery at any time.Without continuous traction,upper limb nerve and vascular damage caused by traction can be avoid.But the incidence of cerebral ischemic events in patients may increase in the BCP.There is also possibility of the nerve damage of the pillow small nerve,great auricular nerve,lateral femoral cutaneous nerve and other nerves.In theory the risk of air embolism in the patients will increase in the BCP,and the cost of setting the position is also higher than the LDP.While in the LDP due to the patient's forearm continuous traction,the surgeon can get a more extensive operating space,and the occurrence of cerebral ischemic events is very rare.In the treatment of anterior shoulder instability after shoulder arthroscopic surgery,there is a lower recurrence rate in the LDP.The cost of setting the position is also significantly lower than the BCP.Of course,the disadvantages of the LDP is also obvious.In the LDP,the brachial plexus and other nerves or vascular injury may increase due to the continuous traction of the forearm.Meanwhile sustained traction in the LDP is also a risk factor for thrombosis,and so on.Therefore,there is still a debate about the optimal location of the shoulder arthroscopy.Many clinicians choose shoulder arthroscopic position based on their own experience and habits.
8.Epidemiological analysis of Galeazzi fractures from 2003 through 2012 in The Third Affiliated Hospital to Hebei Medical University
Jiayuan SUN ; Jialiang GUO ; Zongyou YANG ; Lei LIU ; Xiaodong CHENG ; Ye TIAN ; Bing YIN ; Bo LIU ; Song LIU ; Yansen LI ; Yanbin ZHU ; Yingze ZHANG
Chinese Journal of Orthopaedic Trauma 2017;19(8):703-707
Objective To analyze the epidemiological features of Galeazzi fractures from 2003 through 2012 in The Third Affiliated Hospital to Hebei Medical University. Methods We retrospectively analyzed the data of Galeazzi fractures between January 2003 and December 2012 in the Third Affiliated Hospital to Hebei Medical University. The data from 2003 through 2008 were defined as group A and those from 2008 through 2012 as group B. The general information was compared between the 2 groups. The epi-demiological characteristics and trends during the 10 years were analyzed concerning gender, age and fracture type of the patients. Results A total of 153 Galeazzi fractures were recorded, accounting for 0. 81% of ulnoradial fractures and 0. 12% of all fractures. There were 109 males and 44 females, with a male/female ratio of 2. 48:1. The age range from 11 to 20 years had the highest constituent ratio ( 22. 22%) and type Ⅱthe highest proportion ( 76. 47%) . There were 74 cases in group A, with a male/female ratio of 2. 22:1. There were 79 cases in group B, with a male/female ratio of 2. 76:1. There was no significant difference between the 2 groups concerning the male/female ratio ( P > 0. 05 ) . The median age for group A was 29 years, significantly younger than that for group B ( 34 years ) ( P <0. 05 ) . The high risk age was from 11 to 20 years in group A (32. 43%) and from 21 to 50 years (22. 78%) in group B. Compared with group A, the constituent ratio of age range from 11 to 20 years in group B was significantly lower and the constituent ratio of age range from 41 to 50 years significantly higher ( P <0. 05 ) . There were no significantly differences between the 2 groups concerning the constituent ratio of each fracture type ( P> 0. 05 ) . Conclusions Galeazzi fractures accounted for 0. 81% of ulnoradial fractures and 0. 12% of all fractures. There were more male patients than female ones. The age range from 11 to 20 years and typeⅡhad the highest constituent ratios. Compared with the first 5 years, the latter 5 years witnessed increased mean age.
9.Application of ocular-vestibular evoked myogenic potentials in patients with Meniere's disease.
Xiaolin BAO ; Hua XU ; Qiang SUN ; Jialiang GUO
Journal of Clinical Otorhinolaryngology Head and Neck Surgery 2013;27(1):22-24
OBJECTIVE:
To evaluate the reliability and the value of clinical application of ocular-vestibular evoked myogenic potentials in the patients with Meniere's disease.
METHOD:
Thirty healthy people (control group) and Twenty-seven patients with lateral Meniere's disease (therapy group) were underwent clinical audiological audiometer test and the ocular-vestibular evoked myogenic potential test.
RESULT:
In the control group, the average potential of n10 wave was (10.13 +/- 0.48)ms, and the average potential of p15 wave was (15.23 +/- 0.46)ms. The average amplitude of n10-peak to p15-peak were (6.58 +/- 2.65) microV. According to the control group, eight patients had abnormal waveform, and nineteen with normal in the therapy group.
CONCLUSION
The oVEMPs test is a modest stimulus to the subject which is brief, safe and objective. It represented the function of the utricle and the superior vestibular nerve, the procedure is easily repeatable and acceptable, and worthily applied in patients with Meniere's disease.
Adult
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Case-Control Studies
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Female
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Humans
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Male
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Meniere Disease
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diagnosis
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physiopathology
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Middle Aged
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Reproducibility of Results
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Vestibular Evoked Myogenic Potentials
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Vestibular Nerve
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physiopathology
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Young Adult
10.Hysterosalpingographyand MRIfeaturesofintrauterineadhesion
Jialu XU ; Minghua SUN ; Jialiang ZHU ; Qunying HUANG
Journal of Practical Radiology 2019;35(3):403-406
Objective Toevaluatehysterosalpingography(HSG)and MRImanifestationsofintrauterineadhesion(IUA).Methods 40patientswithIUAconfirmedbyhysteroscopyunderwentHSGand MRIexamination.Wefoundoutthefeaturesofthoseimages, andworkedoutthedetectablerateofeachexamination.Results Inall40patients,19patientsweremildIUAprovedbyhysteroscopy,in which10patientswerediscoveredbyHSG,10patientsby MRIT2WI,16patientsby MRICUBE.16patientsweremiddleIUA,in which9patientswerediscoveredbyHSG,10patientsbyMRIT2WI,16patientsbyMRICUBE.5patientsweresevereIUA,allpatients werediscoveredbyHSG,MRIT2WIand MRICUBE.Andinallcases,therewere12casesofmembraneadhesions,inwhich5cases wereshowninHSG,8casesinMRIT2WIand10casesinMRICUBE.23caseswerefibrousadhesions,inwhich12caseswereshown in HSG,17casesinMRIT2WIand22casesinMRICUBE.5patientsweremuscularadhesions,allpatientswerediscoveredbyHSG, MRIT2WIandMRICUBE.Conclusion ComparingtoHSG,MRIexaminationshowshigherdetectablerateofIUA.MRICUBEsequences playsanimportantpartinthediagnosisofIUA.