1.Anatomic and clinical significance of the anterolateral hip joint capsule and iliofemoral ligament
Jiajie LIN ; Yujin TANG ; Xiufeng HUANG ; Kegong XIE ; Ke HUANG ; Ningning QIAO
Chinese Journal of Tissue Engineering Research 2016;(2):218-223
BACKGROUND:To repair and reconstruct the joint capsule and surrounding ligaments is one of effective methods against displacement and dislocation after total hip arthroplasty. In recent years, anterolateral total hip arthroplasty has been widely used, but little is reported on the anatomic features of the anterolateral hip joint capsule and iliofemoral ligament. OBJECTIVE:To investigate the anatomic features of the anterolateral hip joint capsule and iliofemoral ligaments, thereby providing anatomic evidence for selecting and optimizing the approach for total hip arthroplasty and for clinical practice. METHODS:Thirty adult cadaver hips fixed with formalin were used for this study. The anterolateral hip joint capsule and the iliofemoral ligaments were dissected and anterolateral hip joint capsules were divided into three sections and nine parts. The average thickness of each part and the average height and width of each section were measured. The anterolateral hip joint capsule was observed by its beginning and ending, course, branch and histological features. RESULTS AND CONCLUSION:The anterolateral hip joint capsule was tightly connected with the iliofemoral ligaments to form a complex. The thickness of the capsule was varied. The thinnest parts of the complex were BI and BII. In addition, the average height and width of each section were different. The joint capsule originating from the anterior inferior iliac spine and acetabulum was divided into three branches and fixed on the intertrochanteric line. Understanding of the anterolateral hip joint capsule and iliofemoral ligaments may make for the approach selection, design and optimization of total hip arthroplasty.
2.Impact of subtropical climate on frequency of ambulance use for trauma patients in a coastal area of China.
Yuqiang CHEN ; Yucheng LAI ; Jiajie KE ; Yuefeng CHEN ; Yuling XU ; Yuqin MA ; Jiayin YUAN ; Tian LIANG ; Pengzhan MAI ; Changmin LIN ; Yang XIE ; Keng HUANG
Chinese Journal of Traumatology 2015;18(3):141-146
PURPOSETo explore the impact of subtropical maritime monsoon climate on the frequency of ambulance use for trauma patients in a coastal region in China.
METHODStatistical analysis of data on ambulance use from the 120 Emergency Command Center in Shantou City, Guangdong Province, from January to December 2012 as well as daily meteorological data from a Shantou observatory was performed to determine how climatic factors (seasons, time, and weather) affect the frequency of ambulance use for trauma patients.
RESULTSThe daily ambulance use for trauma patients differed between spring and summer or autumn (p<0.05), between sunny and rainy days (p<0.05), and between cloudy and lightly or moderately rainy days (p<0.05).We found a linear correlation between daily maximum temperature and daily ambulance use for trauma patients (R² =0.103, p<0.05). In addition, there was significant difference in ambulance use between good and bad weather (p<0.05).
CONCLUSIONFrequency of ambulance use for trauma patients is affected by the subtropical maritime monsoon climate in the coastal region. Better weather contributes to increased daily frequency of ambulance use, which is the highest in autumn and lowest in spring.
Ambulances ; China ; Climate ; Humans ; Retrospective Studies ; Wounds and Injuries ; therapy
3.ClinicalstudyofnonGpresseddirectmethodinCTimagingoflowerextremityvein
Junpeng WANG ; Jiajie CHEN ; Lin SUN ; Wenrong FU ; Ke WU ; Wei XUE ; Mingxia LIN ; Yabin ZHANG
Journal of Practical Radiology 2019;35(5):819-821
Objective Toinvestigatetheeffectofpressureandnon-pressureonthedirectimagingoflowerlimbdeepveinswith CTvenography(CTV).Methods 100patients(50malesand50females,aged30-80yearsold,mean (63.5±13.5yearsold)with suspectedlowerextremityvenousdiseasesfrom September2015to October2018 wereretrospectivelyanalyzed.50patientswere scannedafterpressingtheankle(controlgroup),andtheother50werescannedwithoutpressingtheankle(experimentalgroup).Results Therewerenosignificantdifferencesbetweenthecontrolandexperimentalgroupsintheauxiliaryveinscore (t=-0.20,P=0.82), femoralveinscore(t=-0.1,P=0.91),andtotaliliacveinscore(t=-0.03,P=0.97).Conclusion CTV withoutpressingtheankle demonstratescomparableefficacytodirectimagingoflowerlimbdeepveins,withgoodimagequality,reducedcomplicationsandeasy toapply,sothatitshouldbewidelyusedinclinicalpractice.
4.Comparison of effectiveness,safety,and economy of generic and original levetiracetam concentrated solution for injection:a real-world study
Yingnan FENG ; Xianzhe DONG ; Jing PENG ; Ke WANG ; Zhizhou WANG ; Jiajie LUAN ; Lan ZHANG ; Xiaolin YUE
Chinese Journal of Pharmacoepidemiology 2024;33(2):152-157
Objective To evaluate the effectiveness,safety and economy of the clinical application of levetiracetam(LEV)concentrated solution for injection generic drug and the original drug in the national centralized volume-based procurement.Methods The information of inpatients using original LEV concentrated solution for injection in the Xuanwu Hospital of Capital Medical University(original drug group)and inpatients using generic LEV concentrated solution for injection in the First Affiliated Hospital of Wannan Medical College(generic drug group)was retrospectively analyzed after the implementation of the procurement policy(from November 2021 to March 2022).To compare the effectiveness,safety and economy of the two in the prevention and treatment of epilepsy.Results In the original drug group and the generic drug group,18 and 17 patients were enrolled in the treatment of epilepsy respectively,the effective rates were 50.00%and 58.82%,the incidence of adverse reactions were both 0%,and the median daily cost was 255.00(255.00,510.00)yuan and 131.78(131.78,131.78)yuan.After propensity score matching,both the original drug group and the generic drug group had 76 patients each received preventive medication,the effective rates were 97.37%and 100%(P>0.05),and the incidence of adverse reactions were both 0%.The median daily fee for the original the generic drug group was 170.00(170.00,170.00)yuan and 131.78(131.78,131.78)yuan,there were significant difference(P<0.01).Conclusion The clinical effect of generic and original LEV concentrated solution for injection in preventing epilepsy is basically the same,the clinical safety are equivalent,the generic has better economy than the original.The effective rate of the treatment of epilepsy is similar,while the sample size needs to be further expanded to verify the results.
5.Femoral neck system and cannulated compression screw fixation in the treatment of femoral neck fracture in the young and middle-aged patients: efficacy comparison
Jiajie LIU ; Dongze LIN ; Peisheng CHEN ; Chaohui LIN ; Bin CHEN ; Ke ZHENG ; Shunze ZHENG ; Susu TANG ; Fengfei LIN
Chinese Journal of Trauma 2023;39(8):721-729
Objective:To compare the efficacy of femoral neck system (FNS) and cannulated compression screw (CCS) in the treatment of femoral neck fracture in the young and middle-aged patients.Methods:A retrospective cohort study was conducted to analyze the clinical data of 91 patients with femoral neck fracture admitted to Fuzhou Second Hospital from July 2020 to December 2021, including 52 males and 39 females; aged 23-65 years [(48.9±10.3)years]. Garden classification of the fracture found that 31 patients were with type I, 9 with type II, 12 with type III and 39 with type IV. Pauwels classification of the fracture found that 7 patients were with type I, 33 with type II and 51 with type III. A total of 53 patients were treated with FNS fixation (FNS group) and 38 patients with CCS fixation (CCS group). The operation time, intraoperative blood loss, Haidukewych fracture reduction quality, hospitalization time, Barthel index, fracture healing time, and weight-bearing time were compared between the two groups. The hip function was assessed by Harris hip score in both groups at postoperative 3 months, 6 months and 1 year and at the final follow-up. The incidences of postoperative complication and secondary surgery were also compared between the two groups.Results:All the patients were followed up for 15-31 months [(22.2±5.5)months]. There were no significant differences in the operation time, Haidukewych fracture reduction quality, hospitalization time, or Barthel index (all P>0.05). The intraoperative blood loss in the FNS group was 50.0(20.0,85.0)ml, which was more than that in the CCS group [20.0(10.0,50.0)ml] ( P<0.01). The fracture healing time, partial weight-bearing time, and full weight-bearing time in the FNS group [4.0(3.0,5.0)months, 3.0(2.0,3.0)months, 5.0(4.5,6.0)months] were shorter than those in the CCS group [6.0(5.0,7.0)months, 3.0(2.8,4.0)months, 6.0(6.0,7.0)months] (all P<0.01). The Harris hip score at postoperative 3 months, 6 months and 1 year and at the final follow-up were 74.0(71.0,77.0)points, 87.0(84.0,88.5)points, 91.0(88.0,95.0)points, and 94.0(91.0,96.0)points in the FNS group, significantly higher than those in the CCS group [73.0(70.0,74.0)points, 82.5(79.8,87.0)points, 88.0(83.5,91.0)points, 89.0(84.0,93.0)points] (all P<0.05 or 0.01). There were no statistically significant differences in the incidences of postoperative complication or secondary surgery between the two groups (all P>0.05). Conclusion:Compared with CCS, FNS can shorten fracture healing time, allow patients to carry full weight as soon as possible, and significantly improve hip function in the treatment of middle-aged and young adults with femoral neck fracture, although there is more intraoperative blood loss.
6.Risk factors for moderate and severe femoral neck shortening in displaced femoral neck fractures following treatment by a femoral neck system
Dongze LIN ; Peisheng CHEN ; Chaohui LIN ; Bin CHEN ; Ke ZHENG ; Shunze ZHENG ; Jiajie LIU ; Fengfei LIN
Chinese Journal of Orthopaedic Trauma 2023;25(11):952-958
Objective:To investigate the incidence of and risk factors for femoral neck shortening in young and middle-aged patients with displaced femoral neck fracture treated by a femoral neck system (FNS).Methods:A retrospective study was conducted to analyze the clinical data of 135 patients with displaced femoral neck fracture who had been treated by closed reduction and FNS internal fixation at Department of Orthopaedics, The Second Hospital of Fuzhou from December 2019 to December 2021. There were 85 males and 50 females, with an age of 51 (42, 57) years and a body mass index of 22.6 (20.9, 24.2) kg/m 2. According to the Garden classification, there were 29 cases of type Ⅲ and 106 cases of type Ⅳ. Femoral neck shortening was observed. The patients' gender, age, side of shortening, body mass index, fracture type, high-energy injury, time from injury to surgery, cortical comminution at the fracture end, reduction quality (Garden index), partial weight bearing time, complete weight bearing time, and functional evaluation (Harris score) were recorded for a univariate analysis. Multivariate logistic regression was used to analyze the influencing factors for moderate to severe shortening. Results:All the 135 patients were followed up for 17.2 (15.0, 20.2) months. Different degrees of femoral neck shortening happened in all patients, yielding an incidence of 100%(135/135). The femoral neck shortening was 4.2 (2.6, 7.7) mm in displaced femoral neck fractures fixated by FNS. The shortening continued to worsen within the first 3 months after operation, reaching a stable state in the first 6 months. Persistent shortening hardly occurred after 6 months. According to the shortening distance, the patients were divided into a mild shortening group (76 cases <5 mm) and a moderate to severe shortening group (59 cases ≥ 5 mm). The Harris score at the last follow-up in the mild shortening group (91.7 ± 2.3) was significantly higher than that in the moderate to severe shortening group (87.9 ± 3.8) ( P<0.001). The fracture healing rate was 98.7% (75/76) in the mild shortening group and 98.3% (58/59) in the moderate to severe shortening group, showing no significant difference ( P=1.000). Logistic regression analysis found that the risk factors for moderate to severe shortening were fracture type (type Ⅳ) ( OR = 10.227, 95% CI: 1.845 to 56.693, P = 0.008), cortical comminution at the fracture end (if present) ( OR=52.697, 95% CI: 9.870 to 281.352, P<0.001), and partial weight bearing time <4 weeks ( OR = 0.168, 95% CI: 0.032 to 0.893, P = 0.036). Conclusions:The incidence of femoral neck shortening may be high in young and middle-aged patients with displaced femoral neck fracture treated by FNS, leading to decreased hip function. The main risk factors for femoral neck shortening are fracture type (Garden type Ⅳ), cortical comminution at the fracture end and partial weight-bearing time less than 4 weeks.