1.THE ETIOLOGY, PREVENTION AND TREATMENT OF THE SYMPTOM RECURRENCE AFTER OPERATION FOR CHOLE-DOCHOCELE
Wejjin SHI ; Fu JI ; Jianhua SUN ; Siwen ZHANG ; Guangjie JIAG
Chinese Journal of Current Advances in General Surgery 1998;0(01):-
objective To discuss the possible reasons responsible for the symptomrecurrence after operation for choledochocele, prevention and treatment. Methods By analyzing the symptom recurrent cases among 76cases of choledochocele who were treated in our hospital during the period from March 1966 to September 1997, we discuss the possible reasons responsible for the symptom recurrence after operation for choledochocele and its prevention and treatment. Result The possibility of symptom recurrence has no relationship with the age, sex and the type of the cyst. But it is closely related to the opportunity and method of operation (p
2.The association between single nucleotide polymorphism analysis of tryptophan hydroxylase isoform gene rs11178997 and depression and suicidal behavior
Yanjie YANG ; Lin WANG ; Jingsong MA ; Xiuxian YANG ; Xiaohui QIU ; Zhengxue QIAO ; Sijia ZHANG ; Na ZHAO ; Jiag SHI ; Nan NING
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(8):684-686
ObjectiveTo explore the relationship between single nucleotide polymorphism analysis of a novel tryptophanhydroxylase isoform(TPH2)gene rs11178997and depression,and suicidal behavior.MethodsThe specimens of peripheral blood were collected from Chinese Northern 300 depression and 300 controis.The amplification of TPH2 gene rs11178997 was executed by realtime-polymerase chain reaction (realtime-PCR),and analyzed by directed sequencing.And the association between the polymorphisms of TPH2 gene and depression and suicidal behavior was analyzed with SPSS 17.0.ResultsThe genotypic frequencies of the SNPs did not deviate from Hardy-Weinberg equilibrium both in patient and control groups (P > 0.05 ).Compared with control group,significant difference of genotypes and alleles of TPH2 gene rs1 1178997 single nucleotide polymorphism had been found in patient group (75.7% vs 39.7%,6.0% vs 1.3%,18.3% vs 1.3% ; P< 0.05 for all),and the AA genotype frequency of rsl 1178997 was significantly higher in patients.Meanwhile there were not significant differences between genotypes of TPH2 gene rs11178997 and suicide behavior in patient group.Suicidal behavior of depression patients in allele genotypes was higher than nonsuicide behavior of depression patients (P >0.05).ConclusionTPH2 gene rs4570625 single nucleotide polymorphisms have association with the susceptibility of depression.
3.Social support and its influencing factors of postoperative cancer patients undergoing chemotherapy
Jiag ZHANG ; Zheng LI ; De-Juan KONG
Chinese Journal of Modern Nursing 2008;14(15):1659-1661
Objective To explore the state of social support and its influencing factors in patients with cancer diagnosis during chemotherapy in China. Methods 294 cancer subjects received first chemotherapy after operation were investigated with questionare, including social support scale and basic demographic form. Results The average score of social support was (46.26±6.96) , for objective social support was (12.05±3.18), subjective social support was (26.57±4.07) and utilization of social support was (7.63±2.23). Income and marital status influenced the state of social support(F=30. 43, F=18.46, P<0. 001). Conclusions The results show that the most cancer patients during chemotherapy have higher level of social support, Identified affecting factors of the state of social support were income and marital status. Therefore, nurses should help patients to use social support to improve their mental health.