1.Influence of psychological intervention on the quality of life in the hysteromyoma patients with surgery
Xiaoling ZHANG ; Jiachun WANG ; Qingxian ZHU
Clinical Medicine of China 2010;26(7):690-693
Objective To explore the influence of psychological intervention on quality of life(QOL) in the hysteromyoma patients underwent surgery. Methods Three hundred and twenty patients with hysteromyoma were divided into the psychological intervened group ( all cases were treated with the comprehensive psychological intervention) and the control group (without intervention). Before and after treatment, the scores of the Olson's Enrich Questionary and the Nottingham Health Poofity (NHP) were assessed in the two groups. Results Before surgery, the scores of N HP and Olson were not significantly different between the psychological intervened group and the control group ( P > 0. 05 ). The scores of NHP of total hysterectomy in the control group after surgery were higher than that before surgery,and the scores of Olson were lower significantly ( P <0. 05 or P <0. 01). The scores of NHP of subtotal hysterectomy, myomectomy and blood vessel involvement treatment in the control group after surgery were significantly lower than that before surgery, and the scores of Olson were higher ( P < 0. 05 or P < 0. 01 ). After surgery,the scores of NHP of all patients in the psychological intervened group were significantly lower than that in the control group,and the scores of Olson were higher significantly (P <0. 05 or P <0. 01). There was no significant difference in ovarian hormones level between pre- and post- surgery (P > 0. 05). Conclusions The comprehensive psychological intervention pre- and post- surgery is good for the quality of life in hysteromyoma patients.
2.Determination of Swertiamarin in Lomatogoniopsis alpina by HPLC
Xiuqiao ZHANG ; Fengjiao HUANG ; Jiachun CHEN
Chinese Journal of Information on Traditional Chinese Medicine 2006;0(08):-
Objective To establish a method for content determination of swertiamarin in Lomatogoniopsis alpina. Methods HPLC method for determination was used. Chromatographic column: Alltimal C18 (250 mm?4.6 mm, 5 ?m). Mobile phase: methanol-water (including 0.05% H3PO4), and gradient elution. Flow rate:1 mL/min. Wavelength:234 nm. Column temperture:30 ℃. Results The calibration curve of swertiamarin was in good linearity over the range of 3.10~30.98 (r =0.999 1). The average recoveries were 98.0%, with RSD=2.66% (n =6). Conclusion It is a simple and sensitive method in controlling the quality of Lomatogoniopsis alpina.
3.The improving effect and mechanisms of Rhodiola compound on memory-damaged mice
Shu ZHANG ; Zhifa ZENG ; Zhiyong CHU ; Jiachun WANG
Chinese Journal of Behavioral Medicine and Brain Science 2012;21(9):797-799
ObjectiveTo investigated the effects of Rhodiola Compound on improving the intellective function in mice and provide the basis for clinical application.MethodsMice were divided to different groups of three doses of rhodiola compound (0.3 g/kg,0.6 g/kg,1.2 g/kg) and swimming abilities were tested.Other mice were administrated single dose of compound rhodiola( 1.2 g/kg) and training by Morris water maze.Drug's improving intelligence function was assessed using memory acquisition impaired models made by scopolamine or alcohol.When the Morris water maze test was finished,mice were killed and brains were removed immediately to measure SOD and NO levels.ResultsGroups of three doses of compound rhodiola could significantly prolong the swimming time(P < 0.05,P < 0.01 ).Compound Rhodiola group can significantly reduce the swimming distance than the untreated group( ethanol model group:(26 906.6 ± 2769.7 ) mm,RCE treated group:( 19 586.1 ± 6826.7 ) mm ; P <0.05 ).Swimming distance and time of cross-platform quadrant was significantly increased,comparing with model group (P < 0.05 ).Compound Rhodiola significantly enhanced the activity of mouse brain's SOD ( Scopolamine model group:( 150.3 ± 17.7 ) U/ml,RCE treated group:( 197.9 ± 16.8 ) U/ml ; P < 0.05 ) and NO levels ( Scopolamine model group:( 44.7 ± 16.7 ) μmol/gprot,RCE treated group:( 65.4 ± 14.5 ) μmol/gprot ; P < 0.05 ) significantly.ConclusionCompound Rhodiola could promote mice learning and memory function,SOD and NO in brain maybe play a important role in this effect.
4.Management of extracorporeal circulation for totally robotic assisted cardiac surgery
Jiali WANG ; Changqing GAO ; Jiachun LI ; Too ZHANG ; Lan MA
Chinese Journal of Thoracic and Cardiovascular Surgery 2011;27(7):407-408
Objective To discuss the way and management of extracorporeal circulation (ECC) for totally robotic assisted cardiac surgery. Methods A Total of 226 patients underwent cardiac surgery using da Vinci S robotic surgical system, including 111 patients underwent atrial septal defect repair ( ASDR) , 9 patients underwent ventricular septal defect repair ( VSDR) ,51 patients underwent mitral valvuloplasty ( MVP) , 20 patients underwent mitral valve replacement( MVR) , 27 patients underwent left atrial myxoma excise and 4 patient underwent right atrial myxoma excise. ECC for most of patients was achieved with femoral arterial cannula, femoral venous cannula and right internal jugular venous cannula, except for 1 patient underwent MVP with femoral arterial cannula and femoral two-stage venous cannula. In all the cases, vacuum-assist venous drainage ( VAVD) , continuous blood gas monitoring and ultrafiltration were used during ECC. myocardial protection was pertic cross-clamp time was 40 ~219 (105.9+38. 8)min and 21 ~166 (69.5±30.0)min respectively. During ECC, the mean urine volume was 100-2100 (771.7±477.6) ml, ultrafiltration volume was 1000-4800 (2495.4 ±811.6) ml, and the total fluid balance was subzero-balanced (172 cases) or zero-balanced(13 cases) in most of patients. Conclusion The establishment of ECC system through peripheral vessels, using VAVD and continuous blood gas monitoring are the key points of ECC for totally robotic assisted cardiac surgery, also certain learning curve of perfusion technique and close communication between the surgical team are essential during ECC.
5.Application of MR perfusion imaging in evaluation of hemodynamic of patients with moyamoya disease
Xinwei JU ; Shuai ZHANG ; Jiachun FENG ; Dan TONG
Journal of Jilin University(Medicine Edition) 2016;42(5):1024-1029
Objective:To evaluate the hemodynamic situation of the patients with moyamoya disease using MR perfusion imaging,and to explore the relationship between compensatory collateral circulation and perfusion. Methods:Seventy-two hospitalized patients with moyamoya disease were selected as typical moyamoya disease group,including 37 males and 35 females,aged 10 - 62 years old,all patients underwent cerebral angiography (DSA)and MR perfusion imaging.And 20 patients with out neurological history were used as control group.With mean transit time (MTT)image as a standard,the abnormal perfusion ranges were classified as region of interest (ROI),and the corresponding perfusion parameter values,including cerebral blood flow (CBF),cerebral blood volume (CBV),MTT and time to peak (TTP)were recorded,respectively.The cerebellum was used as a reference in this study,the perfusion parameters were standardized,and the relative ratios of the perfusion parameters (rMTT,rTTP,rCBF,rCBV)were obtained.Results:Compared with control group,the rMTT and rTTP of the patients in typical moyamoya disease group were prolonged and the rCBF was reduced (P <0.05 or P < 0.01), but the rCBV had no obvious difference (P >0.05).②Compared with the contralateral side,the rMTT and rTTP of the suffered side were prolonged,and the rCBF and rCBV were reduced (P < 0.05 or P < 0.01).Compared with chronic onset group,the rCBV and rCBF of the patients in acute onset group were reduced (P <0.05 or P <0.01),but the rMTT and rTTP had no statistically significant difference (P > 0.05).There were no significant differences in all parameters between hemorrhagic moyamoya disease group and ischemia group (P > 0.05 ). Conclusion:MR perfusion imaging can accurately evaluate the hemodynamic condition of moyamoya disease;MTT and TTP hve higher sensitivities than CBF and CBV.MR perfusion imaging can evaluate the compensation of collateral circulation of moyamoya disease and provide the objective basis for the clinician to select the proper surgical timing and the best operation methods.
6.Textual Research of Chinese Herb Maidong
Yajun GONG ; Jie ZHANG ; Zhinan XIANG ; Chenggao ZHOU ; Jiachun CHEN
China Pharmacist 2017;20(2):229-231
Objective:To perform textual researches on name, origin and distribution of Maidong to clarify the medicinal varieties and history recorded in ancient literatures and provide evidence for clinical use. Methods:Ancient herbal works were performed textual research, and the resource investigation and modern data were analyzed. Results:According to the ancient herbal records and modern researches, Maidong had lots of alias, while only Maimendong and Maidong were used as the medicine common names. According to the records of main origin, original plant morphological and medicinal characteristics of Maimendong, it was preliminarily concluded that Maidong recorded in the ancient herbal records was mainly produced in Jiande of Zhejiang province, Mianyang of Sichuan prov-ince, Xiangyang of Hubei province and the surrounding areas. The chemical compositions and pharmacological activities of Maidong and Shanmaidong were similar;therefore, they both could be used as the medicines. Conclusion:In the light of the ancient and mod-ern medicinal customs, modern chemistry and pharmacology researches and clinical practice of TCM, it deserves further discussion on whether Maidong and Shanmaidong can be used as multi source varieties of traditional Chinese medicines just like Polygonaceae plants palmatum L. , Rheum tanguticum Maxim, ex Balf. and Rheum officinale Baill. , and Ranunculaceae plants Coptis chinensis Franch. , Coptis deltoidea C. Y. Cheng et Hsiao and Coptisteeta Wall.
7.Evaluation of susceptibility weighted imaging in defining penumbra during acute stage of cerebral infarction and comparison with perfusion weighted imaging
Song LUO ; Fang DENG ; Ying ZHANG ; Jing MIAO ; Ying CHEN ; Lijuan WANG ; Jiachun FENG
Chinese Journal of Neurology 2014;47(10):711-715
Objective To evaluate whether susceptibility weighted imaging (SWI) can be used in definition of penumbra during acute stage of cerebral infarction,compared with perfusion weighted imaging (PWI).Methods Ischemic stroke patients within 3 days after onset were included.They adopted multimodal magnetic resonance imaging examination,including regular magnetic resonance imaging sequence (T1 WI,T2 WI and T2-weight fast fluid-attenuated inversion-recovery),diffusion weighted imaging (DWI),PWI and SWI.Alberta Stroke Programme Early CT Score was done on DWI,SWI and PWI.The mismatch of SWI-DWI (minimal indensity projection (mIP)-DWI) was compared with that of PWI-DWI (mean transit time (MTT)-DWI) and analyzed statistically.The application of prominent vein (PV) on SWI as a sort of alternation of cerebral blood volume (CBV) and direct observation of thrombosis in arteries on SWI were done.Results The SWI-DWI (2.39 ± 1.42) and the MTT-DWI (2.72 ± 1.49) mismatch showed no statistically significant difference (r =0.726,P > 0.05).The grade of PV was positively related with the CBV of the ipsilateral brain tissue on admission (r =0.564,P < 0.05).SWI showed the similar ability with magnetic resonance angiography to judge responsible blood vessels with susceptibility vessel sign.Conclusion SWI-DWI can evaluate the ischemic penumbra.PV may reflect the increased blood volume of the lesion side of the brain tissue.SWI can reveal the thrombosis of the responsible vessels.
8. Hepatitis B seroepidemiological investigation among healthy people of Tianmen city
Liming WEI ; Jiachun TAO ; Jiaoping ZHANG
Chinese Journal of Experimental and Clinical Virology 2017;31(5):438-440
Objective:
To understand the hepatitis B (HB) infection status among healthy people of Tianmen city, and to evaluate the effect of undertaking vaccination against hepatitis B, and to direct the work of HB prevention and control.
Methods:
Multi-stage random sampling was applied to 5 among the 27 townships of Tianmen city, 398 and 1 756 persons of age between 1 and 59 years were sampled in 2006 and 2012, respectively, blood samples were collected, HBsAg, HBsAb, HBeAg, HBeAb and HBcAb were tested by ELISA; database was established with Epidata 3.1 and data were processed and analyzed by SPSS 13.0.
Results:
The infection rates among the healthy people aged between one year and 59 years in 2006 and 2012 were 38.44% and 19.25% respectively with significant difference (χ2=67.92,
9.A preliminary interview of cognitive behavioral therapist: The reason why they chose CBT and how they use it in therapies
Siqi CHEN ; Shujie ZHUANG ; Xiuming ZHANG ; Mingyi QIAN ; Jingjing YANG ; Tianyue MI ; Juling WAN ; Haiyang WEI ; Jiachun WANG
Chinese Mental Health Journal 2017;31(1):46-51
Objective:To investigate the clinical application of cognitive behavioral therapy (CBT) and the reasons of the choosing CBT.Method:Totally 14 psychotherapists accepted a semi-structured interview,including their backgrounds of CBT training,the application of CBT in psychotherapy,their attitude toward consultative relations,their opinion on comparing other schools with CBT,and their reasons for choosing CBT.Results:The main reasons for choosing CBT included the influence of important others,the characters of CBT and personal factors.In clinical practice,the most commonly used behavioral techniques included exposure therapy,roll play,relaxation Waining and so on.The most commonly used cognitive techniques included Socratic questioning,cognitive restructuring and challenge unreasonable cognition.Conclusion:Cognitive behavioral therapy (CBT) is suitable for those who are sensible and preferring structural therapy.Nevertheless,the trend in therapy is the integration of different psychotherapy schools.
10.Spinal dural arteriovenous fistulae associated with perimedullary arteriovenous fistulae: imaging characteristics and surgical treatment.
Jiachun LIU ; Hongtao XIANG ; Feng LING ; Hongqi ZHANG ; Zhongrong MIU
Chinese Journal of Surgery 2002;40(3):191-193
OBJECTIVETo enhance the clinical doctors' cognizance of atypical spinal dural arteriovenous fistulae (SDAVFs) associated with perimedullary anteriovenous fistulae (PMAVFs).
METHODSThe clinical imaging and surgical therapy of 3 patients with PMAVFs were analyzed retrospectively.
RESULTSThe clinical presentations of the 3 patients were not significantly different from those of typical SDAVFs. They were verified by repeated spinal angiography that the anterior spinal artery (ASA) is supplied to the drainage-vein. The 3 patients were treated surgically. First two operations were performed to eliminate the supply of ASA and dural branch, then the supply of the dural branch was amputated, and finally both the ASA and dural branch supplies were excised successfully. Clinical symptoms of the 3 patients were improved after treatment.
CONCLUSIONSIt is necessary to perform thorough spinal angiography in patients with SDAVFs to exclude another fistula. The key point in the treatment of such patients is successfully to terminate both the spinal feeder and dural branch feeder.
Adult ; Aged ; Arteriovenous Fistula ; physiopathology ; surgery ; Humans ; Male ; Middle Aged ; Retrospective Studies ; Spinal Cord ; surgery ; Surgical Procedures, Operative